ACCELERATED STABILITY STUDY OF CHITRAK HARITAKI AVALEHA

Objective: Accelerated stability study of Chitrak Haritaki avaleha was done for six months to know the stability of formulation in reference of its phyto-constituents and microbial growth therein.Methods: Chitrak Haritaki avaleha was made in laboratory following classical method [Sample lab (SL)] as per AFI part-1(The Ayurvedic formulary of India, part-1) and two samples were collected from local market [Market Sample-1(MK-1) & Market sample-2 (MK-2)] of reputed brand. These three samples were put in controlled condition following ICH (International Conference on Harmonization) guidelines for accelerated stability study for six months. The intermediate samplings were done at starting, after one, three and six month respectively. These samples were investigated for reducing sugar, phyto-constituents (Total tannins, piperine, vitamin C and total polyphenols contents), microbial load and their organoleptic characteristics. Results: All the results were calculated and compared for variation during course of time. Variation in the result of samples was evaluated against Arrhenius equation which ensured that formulation was stable over two years and no significant variation was found over six month of accelerated stability condition.Conclusion: Since it is traditional avalehakalpana, the shelf life period was about one year (Sharangdhar Samhita) and updated to three year in Drug and cosmetic rule 1945, 161B. The presented study reflect that Chitrak Haritaki avaleha was stable over two year (by taking inference from Arrhenious equation) and more sophisticated packing may improve the shelf life period.Keywords: Avaleha, Shelf life, Accelerated stability, Chitrak Haritaki avaleha

Acute Myocarditis Presenting as Acute Coronary Syndrome

A 50-year-old male presented to the hospital with an approximate three-week history of nausea, fever, and back pain. Upon initial evaluation he had an electrocardiogram with ischemic changes and initial labs significant for a troponin of >25.0 ng/ml (<0.30 ng/ml), pro b-type natriuretic peptide (proBNP) of 9884 pg/ml (<125 pg/ml), and a lactic acid of 4.3 mmol/L (0.5-1.9 mmol/L). There was a concern for an acute coronary syndrome presenting as cardiogenic shock, but the patient was unable to tolerate left heart catheterization. He had a rapid clinical decline and despite all efforts, he passed away. The initial cause of death was thought to be due to an acute myocardial infarction, however, autopsy results were consistent with acute myocarditis. This case highlights the presentation of acute myocarditis as an acute coronary syndrome with complete heart block.Open access journalThis item from the UA Faculty Publications collection is made available by the University of Arizona with support from the University of Arizona Libraries. If you have questions, please contact us at [email protected]

Effect of Temperature and Period of Storage on Breaking Dormancy in Gladiolus (Gladiolus grandiflorus Hort.) Corms

An experiment was conducted in 2010-2011 at Indian Institute of Horticultural Research, Bengaluru, on three gladiolus cultivars viz., 'Arka Amar', 'Darshan' and 'Kum Kum' to study effects of storage temperature (4°C and room temperature 27±2°C) and length of storage (50, 70 and 90 days) on dormancy of corms. Cv. 'Kum Kum' registered minimum number of days for sprouting (42.71 days), spike emergence (116 days) and days to opening of first floret (128 days). Corms stored at 4°C resulted in lowest number of days for-sprouting (45.24 days), days to spike emergence (114.63 days) and days to opening of first floret (126.60 days) and resulted in highest sprouting percentage (58.7%). Interaction effects revealed that cv. 'Kum Kum' stored at 4°C for 90 days after harvest took minimum number of days to sprouting (25.07 days), days to spike emergence (90.38 days) and days to opening of first floret (102.38 days) resulting in 100% sprouting

Beach Morphological Characteristics and Coastal Processes Along Dakshina Kannada Coast, West Coast of India

Source: ICHE Conference Archive - https://mdi-de.baw.de/icheArchiv

Study on interventions to reduce vibration transmission to power tiller operator

Present study focuses on interventions to reduce vibration transmitted to power tiller operator. In this study two operations (namely: standing mode and transportation) and three forward speeds (1.0, 1.5 and 2.0 kmh-1) were selected. In both selected operations vibration magnitudes were maximum at 2.0 kmh-1. In the standing mode vibration magnitudes in x, y and z direction were 5.83, 1.37 and 2.36 ms -2 at 2.0 kmh-1. In transportation vibration magnitudes were 6.81, 1.49, 2.82 ms-2 respectively in x, y and z direction at 2.0 kmh-1. The selection of vibration isolators were done on the basis of the transmissibility curves and the isolation region. The selected isolators were installed at interface between engine and the chassis. These interventions along with previously developed bush and sheet type interventions reduced vibrations up to 50.24, 69.06 and 59.08 % at 1.0, 1.5 and 2.0 kmh-1 in stationary mode. In transportation vibration reduction were 52.96, 65.98 and 36.67 % at 1.0, 1.5 and 2.0 kmh-1, respectively. The vibration reduction were high in stationary mode than transportation mode because in stationary mode vibration comes only from the engine but in transportation vibration comes from engine and the surface profile as well

YOGA PRACTICE AND BIOCHEMICAL AND PHYSIOLOGICAL ALTERATIONS IN NORMAL SUBJECTS

ABSTRACTObjective: To assess the effect of 45 minute yogic kriya (Surya Namaskar and Kapalbhati) for 30 days on various physiological and biochemicalparameters.Methods: About 20 Nursing College students of the Santosh Medical University, Ghaziabad, between the age group 17 and 21 years volunteered toparticipate in the study. They were divided into two Groups A and B. Group A students including 10 students in each group were subjected to 30 daysyoge kriya for 45 minutes for 6 days in a week. Statistical analysis: A student's t-test was used for comparing the means of pre- and post-yoga resultsof various parameters.Results: No significant difference was found in systolic blood pressure, pulse, body mass index, hemoglobin except for fasting blood sugar and diastolicblood pressure (p&lt;0.001) among the yoga subject while comparing with baseline values and control.Keywords: Yoga, Biochemical alterations, Physiological alterations, Surya Namaskar and Kapal Bhati

Urinary antibiotic activity in paediatric patients attending an outpatient department in north-western Cambodia.

OBJECTIVE: Antibiotic resistance is a prominent public and global health concern. We investigated antibiotic use in children by determining the proportion of unselected children with antibacterial activity in their urine attending a paediatric outpatient department in Siem Reap, Cambodia. METHODS: Caregiver reports of medication history and presence of possible infection symptoms were collected in addition to urine samples. Urine antibiotic activity was estimated by exposing bacteria to urine specimens, including assessment against multiresistant bacteria previously isolated from patients in the hospital (a methicillin-resistant Staphylococcus aureus (MRSA), a multiresistant Salmonella typhi and an extended-spectrum β-lactamase (ESBL)-producing Escherichia coli isolate). RESULTS: Medication information and urine were collected from 775 children. Caregivers reported medication use in 69.0% of children in the preceding 48 h. 31.7% samples showed antibacterial activity; 16.3% showed activity against a local multiresistant organism. No specimens demonstrated activity against an ESBL-producing E. coli. CONCLUSIONS: Antibiotics are widely used in the community setting in Cambodia. Parents are often ill-informed about drugs given to treat their children. Increasing the regulation and training of private pharmacies in Cambodia may be necessary. Regional surveillance of antibiotic use and resistance is also essential in devising preventive strategies against further development of antibiotic resistance, which would have both local and global consequences

Gangotri glacier dynamics from multi-sensor SAR and optical data

The present study has analyzed dynamics of Gangotri glacier using multiple remote sensing (RS) datasets and ground based observations. Interferometric Synthetic Aperture Radar (InSAR) data pairs from European Remote Sensing satellite (ERS 1/2) tandem pair for spring of 1996, Sentinel-1 SAR pairs and Japanese's Advance Land Observation System (ALOS) PALSAR-2 SAR data for Spring of 2015 were used to derive glacier-surface velocity at seasonal time scale using Differential InSAR (DInSAR) techniques. Bi-static TanDEM-X (Experimental) data was used for the 1st time to estimate glacier surface elevation changes for a period of 22, 44, 88 days during summer of 2012 using InSAR techniques in this study. Annual glacier velocity was also estimated using temporal panchromatic data of LANDSAT-5 (30 m), LANDSAT-7/8 (15 m), Sentinel-2 (10 m) and Indian Remote Sensing Satellite IRS-1C/1D panchromatic (5 m) data during 1998–2019 with feature tracking approach. This study has estimated glacier surface velocity and surface elevation changes for the major parts of Gangotri glacier and its tributary glaciers using medium to high resolution optical and SAR datasets, at annual and seasonal time scale, which is an improvement over earlier studies, wherein snout based glacier recession or only main glacier velocities were reported. The velocity and slope were used to assess glacier-ice thickness distribution using Glabtop-2, slope dependent and laminar flow based methods over the Gangotri group of glaciers. The estimated ice thickness was estimated in the range of 58–550 m for the complete glacier while few small areas in middle &amp; upper regions carry higher thickness of about 607 m. The estimated glacier-ice thickness was found in the range of 58–67 m at the snout region. The estimation was validated using 2014 field measurements from Terrestrial Laser Scanner (TLS) for the first time and correlation was found to be 0.799 at snout of the glacier.</p