Clinical and Patient-Reported Outcomes After Pancreatoduodenectomy for Different Diseases: A Follow-Up Study.

OBJECTIVE:: The objective of the study was to evaluate clinical features and quality of life (QoL) in a 2-year follow-up study in subjects who underwent pancreatic head resection (PHR). METHODS:: One hundred ninety-seven patients with benign and malignant diseases who underwent PHR were studied. A dedicated clinical form and the European Organisation for Research and Treatment of Cancer Quality-of-Life Questionnaire C-30 were administered at evaluation times (immediately before surgery and 6, 12, 18, and 24 months after discharge). A sample of 197 sex- and age-matched norms was also included into the study as reference group. RESULTS:: Of the 197 patients studied, 164 (83.2\%) had malignant disease, and 33 had benign disease (16.8\%). At initial evaluation, global health was significantly lower (P = 0.001) in the study population as compared with the norms. At the end of the study, the QoL was not significantly different from the norms, although the QoL of the 30 patients with benign disease was significantly better than that of the 72 patients with malignant disease. CONCLUSIONS:: The QoL before PHR was impaired in study patients before resection as compared with the normative population, whereas in patients who survived resection, it significantly improved in the 24 months after surgery

Topic: Mesh and Prosthesis

The development of biologic prostheses has changed the approach to abdominal wall surgery, especially when the use of synthetic mesh is contraindicated. From July 2005 to July 2014, 57 biological prostheses were implanted in 49 patients at the General Surgical Unit D, Dept. of Surgery, Sapienza University of Rome. Results with biologics are encouraging if proper indications and technical details are considered. Our indications take in account guidelines from the Hernia Grading System (HGS) (The Ventral Hernia Working Group, Surgery; 2010)