Genome sequences of equine herpesvirus 1 strains from a European outbreak of neurological disorders linked to a horse gathering in Valencia, Spain, in 2021

Five equine herpesvirus 1 (EHV-1) genome sequences with links to an EHV-1 outbreak with neurological disorders after a horse gathering in Valencia, Spain, in February 2021, were determined. All strains showed the closest relationships to strains from Belgium and the United Kingdom, indicating a common source of infection

Evaluation of the pocH-100iV DIFF hematology analyzer for use in horses and cattle

The results of the analysis of equine and bovine blood samples with the automated pocH-100iV DIFF hematology analyzer were compared with the results obtained with reference methods or other analyzers (Vet ABC, Coulter Counter ZF, Coulter LH 750 analyzer). For equine blood and most parameters in bovine blood good to excellent correlations between methods and analyzers were obtained. For bovine blood good to poor correlations and significant differences were obtained between the pocH-100iV DIFF and other methods or analyzers mainly for hematocrit and hemoglobin determinations and platelet counts. Overall the pocH-100iV DIFF seems to be a reliable and user-friendly analyzer

Anti-inflammatory phytotherapeutics: a valuable alternative to NSAID treatment in horses?

ABSTRACT In equine practice, phytotherapy is meeting the increasing demand of horse owners for "natural", safe treatment methods. Long-term use of NSAIDs can cause severe adverse effects, hence the growing popularity of anti-inflammatory phytotherapeutics. At the current time, several different herbal mixes are being commercialized, which makes it difficult for horse owners and veterinarians alike to make a well-founded choice. Harpagophytum procumbens (devil's claw), Salix spp. (willow) and Ribes nigrum (blackcurrant), three plants that are often used in these mixes, have been evaluated both in vitro and in vivo. Based on published studies and the evaluation of these studies, for example by the Cochrane Collaboration, there seems to be some evidence for Harpagophytum procumbens and Salix spp. having a stronger analgesic and anti-inflammatory effect than placebos in humans. In horses, however, only one limited clinical study on Harpagophytum has been performed up until now, while no studies were found on the use of Salix in horses. More research is needed before any claims concerning efficacy or safety can be made regarding the use of these plants in treating horses. It has also been claimed that Ribes nigrum leaves have an anti-inflammatory effect, though this has not yet been clinically proven either in humans or in horses. Although veterinary phytotherapy is as old as animal husbandry itself, little scientific proof can be found regarding its uses. More research is needed before phytotherapy can be advertised as a valuable and safe alternative to the more conventional treatment protocols. SAMENVATTING In de paardengeneeskunde is fytotherapie een antwoord op de toenemende vraag van eigenaren naar "natuurlijke", veilige behandelmethoden. Het langdurig gebruik van NSAID's kan ernstige bijwerkingen geven, vandaar de groeiende populariteit van ontstekingsremmende fytotherapeutica. Momenteel zijn er meerdere kruidenpreparaten commercieel beschikbaar maar het is moeilijk voor de paardeneigenaar en de dierenarts om hier een verantwoorde keuze uit te maken. Harpagophytum procumbens (duivelsklauw), Salix spp. (wilg) en Ribes nigrum (zwarte bes of cassisbes), drie planten die veel gebruikt worden in de commerciële preparaten, werden zowel in vitro als in vivo geëvalueerd. Op basis van gepubliceerde studies en de beoordeling van deze studies door onder andere de Cochrane Collaboration zijn er aanwijzingen dat Harpagophytum procumbens en Salix spp. bij de mens een groter analgetisch en ontstekingsremmend effect hebben dan een placebo. Bij paarden is er echter slechts één beperkte klinische studie met Harpagophytum uitgevoerd, en het effect van Salix werd nog nooit onderzocht. Om de werkzaamheid en veiligheid van deze planten bij het paard te kunnen beoordelen, dient er meer onderzoek verricht te worden. De bladeren van Ribes nigrum zouden ook een ontstekingsremmende werking hebben, maar dit is momenteel noch bij de mens, noch bij het paard klinisch aangetoond. Hoewel de veterinaire fytotherapie al even lang bestaat als de dierhouderij, is er weinig wetenschappelijk bewijs omtrent een efficiënte werking ervan. Vooraleer men de fytotherapie kan aanraden als een waardevol en veilig alternatief voor de conventionele behandelmethoden, is er duidelijk nog meer onderzoek nodig

Black locust (Robinia pseudoacacia) intoxication as a suspected cause of transient hyperammonaemia and enteral encephalopathy in a pony

Two ponies presented with mild abdominal pain and mild diarrhoea one hour after ingestion of roots of a black locust tree. On admission, symptoms had progressed to depression, weakness and the passing of dark, firm faeces. Treatment was symptomatic and supportive, aiming at the evacuation of the toxin from the gastrointestinal tract. One pony developed severe, reversible neurological signs associated with transient hyperammonaemia in the absence of liver disease. After 24 h the ammonia level returned to normal and central nervous signs disappeared. Both ponies recovered completely. This report describes the ingestion of black locust closely followed by the development of central nervous signs and hyperammonaemia. Increased ammonia absorption due to the intestinal wall inflammation caused by the toxins of the black locust tree, as well as increased ammonia production by enteric bacteria is therefore considered a plausible pathophysiological mechanism of the neurological signs displayed in black locust intoxicatio