Looking for loopholes: processes of incorporation of illegal immigrants in the Netherlands

'Looking for loopholes: processes of incorporation of illegal immigrants in the Netherlands' offers a detailed account of how illegal immigrants, who are legally excluded, manage to incorporate into Dutch society. By combining the perspectives of immigrants on the one hand and of those who have to implement the 'discouragement policy' on the other hand, the study shows how tensions between restrictive rules and day-to-day practices are growing. Based on long-term research in the four largest cities in the Netherlands, attention is paid to the role of informal employment and criminal involvement and to practices in the fields of education, housing, health-care and police surveillance

Immigration, Crime and Criminal Justice Systems

Criminal Justice: Legitimacy, accountability, and effectivit

The impact of one: single cell analysis of T cell states in human cancer

Immune checkpoint therapies that aim to (re)activate the immune response against cancer cells have shown promising results in a variety of tumor types. Yet, a large fraction of cancer patients does not benefit from these therapies. While the presence of a substantial number of immune cells, and in particular T cells, in the tumor is generally related with a better clinical response to checkpoint therapies, the T cells in the tumor are diverse in their capacity to eliminate the tumor. In order to improve treatment outcome of cancer patients, we require a better understanding of the roles of different T cells in the response (and resistance) to immune checkpoint therapy. The development of single cell profiling technologies has provided us with a powerful tool to analyze the state and functionality of individual cells. In this thesis, I have used single cell profiling methods in combination with innovative experimental technologies to unravel the diversity of T cells in human tumors and define the changes in the profiles of T cells that occur in response to treatment with immune checkpoint therapy to dissect which T cells are important for therapy response.LUMC / Geneeskund

Dead or alive? De invloed van incidentkenmerken en gedragingen van actoren op fatale versus niet-fatale uitkomsten van geweld

Sommige ernstige geweldsincidenten eindigen met dodelijke afloop, andere niet. Om te onderzoeken welke factoren bij dit verschil in afloop een rol spelen, bestu-deerden we op basis van strafdossiers in hoeverre een aantal geselecteerde incident-kenmerken en gedragingen van actoren bijdroeg aan de escalatie van conflicten. Hiertoe zijn 267 ernstige geweldsincidenten bestudeerd waarbij daders veroordeeld waren voor fataal geweld (moord/doodslag, N=126) of niet-fataal geweld (poging moord/doodslag, N=141). De resultaten tonen substantiële verschillen tussen conflicten met een fatale en niet-fatale afloop op het punt van incidentkenmerken en vooral van gedragingen van actoren gedurende het incident. De kans op een fatale afloop blijkt vooral toe te nemen wanneer sprake is van alcoholgebruik door slacht-offers, vuurwapengebruik door daders, bepaalde gedragingen geïnitieerd door het slachtoffer en afwezigheid van omstanders. [English language abstract is available]

Zal de strafbaarstelling van illegaliteit effectief zijn? En wil iemand dat eigenlijk weten?

Criminal Justice: Legitimacy, accountability, and effectivit

Waarom zijn vrouwen en meisjes vaker dan mannen en jongens slachtoffer van mensenhandel?

Criminal Justice: Legitimacy, accountability, and effectivit

Foreword. Towards evidence-informed law and policy making in the EU, some introductory notes from a criminologist

Criminal Justice: Legitimacy, accountability, and effectivit

Mensenhandelaanpak in beweging : een kritische blik op de aanpak van arbeidsuitbuiting

Criminal Justice: Legitimacy, accountability, and effectivit