High-energy blunt pelvic ring injury

Table 1: Patients’ demographic and injury characteristicsTable 2: Pelvic ring injuries type A, B & C and concomitant injurie

High-energy blunt pelvic ring injury

Table 1: Patients’ demographic and injury characteristicsTable 2: Pelvic ring injuries type A, B & C and concomitant injuriesTHIS DATASET IS ARCHIVED AT DANS/EASY, BUT NOT ACCESSIBLE HERE. TO VIEW A LIST OF FILES AND ACCESS THE FILES IN THIS DATASET CLICK ON THE DOI-LINK ABOV

High-energy blunt pelvic ring injury

Table 1: Patients’ demographic and injury characteristicsTable 2: Pelvic ring injuries type A, B & C and concomitant injuriesTHIS DATASET IS ARCHIVED AT DANS/EASY, BUT NOT ACCESSIBLE HERE. TO VIEW A LIST OF FILES AND ACCESS THE FILES IN THIS DATASET CLICK ON THE DOI-LINK ABOV

Comparative affinities for penicillin-binding proteins of multipolar ionic amphoteric cephalosporins in Gram-negative bacteria

Chemical modification of the highly reactive 7-aminocephalosporanic acid has yielded many compounds with improved activities and expanded clinical spectra. Introduction of an alpha-oxyimino group in C-7 position has given rise to improved activity against Gram-negative bacteria as a consequence of the high affinity of compounds carrying this substituent for the essential penicillin-binding protein (PBP) 3. The spectrum of activity of oxyimino cephalosporins has been further expanded by introduction of substituents with a quaternary nitrogen in C-3 position. These compounds have maintained their high affinity for the essential PBP 3, typical of the third generation cephalosporins and have acquired an improved ability to cross the outer membranes of Gram-negative bacteria. Among these compounds cefepime also among cephalosporins. exhibits high affinity for PBP 2, a very unusual property among cephalosporins

Lysozyme inhibitors enhance immune response in mice

The effect of hen egg-white lysozyme (HEWL) inhibitors (such as heparin, histidine methylester, chitotriose, chitobiose) on immune response was evaluated by measuring antibody-producing cells and circulating antibodies in mice inoculated with these substances and the test antigen (SRBC or BSA). It was found that these compounds have an immuno-enhancing effect which is directly proportional to their inhibitory activity on HEWL. Conversely, HEWL inhibited the immuno-enhancing effect of these compounds when injected together with these and the test antigen. The results suggest that one possible mechanism by which adjuvants stimulate immune response may be the inhibition of endogenous lysozyme

Lysozyme inhibitors enhance immune response in mice.

The effect of hen egg-white lysozyme (HEWL) inhibitors (such as heparin, histidine methylester, chitotriose, chitobiose) on immune response was evaluated by measuring antibody-producing cells and circulating antibodies in mice inoculated with these substances and the test antigen (SRBC or BSA). It was found that these compounds have an immuno-enhancing effect which is directly proportional to their inhibitory activity on HEWL. Conversely, HEWL inhibited the immunoenhancing effect of these compounds when injected together with these and the test antigen. The results suggest that one possible mechanism by which adjuvants stimulate immune response may be the inhibition of endogenous lysozyme