Super-nonradiative states in fractal quantum systems

Theoretically the relationships of the main parameters of active nanoobjects with the Higgs boson and the Higgs field in a fractal quantum systems, super-nonradiative states of physical fields are investigated. The estimations of numbers, mass and rest energy of the neutrino (solar, electronic), the rest energy of Majorana neutrino, dark matter are obtained

Higgs field and cosmological parameters in the fractal quantum system

For the fractal model of the Universe the relations of cosmological parameters and the Higgs field are established. Estimates of the critical density, the expansion and speed-up parameters of the Universe (the Hubble constant and the cosmological redshift); temperature and anisotropy of the cosmic microwave background radiation were performed

INNOVATIVE MODEL OF TRAINING OFFICERS IN CIVIL UNIVERSITY

The article demonstrates the necessity of expanding the capabilities of the system of higher military institutes and military training centers of civilian universities to ensure the increasing requirements of the Russian Ministry of Defence for training of officers. The article considers the model of the special officers' training for military service under the contract by the innovative educational trajectory on the basis of a civil university, having in his structure the military department (department of military training). The model has been developed at Lobachevsky State University ofNizhni Novgorod (UNN). It enables to prepare an officer for two different fields of study in higher education. The innovative model is presented for officer training area "Foreign regional studies" (Bachelor's programme) followed by training by the programme of "Psychology" (Master). The implementation of innovative model does not require changes to existing legal acts

Evaluation of a novel non-invasive preimplantation genetic screening approach.

OBJECTIVE:To assess whether embryonic DNA isolated from blastocyst culture conditioned medium (BCCM) combined with blastocoel fluid (BF) could be used for blastocyst stage non-invasive preimplantation genetic testing for chromosomal aneuploidy (non-invasive preimplantation genetic screening, NIPGS). PATIENTS:47 embryos from 35 patients undergoing IVF. INTERVENTIONS:DNA analysis of combined BCCM plus BF in comparison with trophectoderm (TE) biopsy and/or whole blastocyst (WB)using next generation sequencing (NGS). RESULTS:Embryonic DNA was successfully amplified in 47/47 NIPGS samples (28 frozen-thawed and 19 fresh culture samples) ranging from 6.3 to 44.0 ng/μl. For frozen-thawed embryos, the concordance rate for whole chromosome copy number per sample was equivalent between NIPGS vs. TE biopsy, NIPGS vs. WB and TE vs. WB samples taken from the same embryo was 87.5%; 96.4% and 91.7% respectively (P>0.05), and the rate of concordance per single chromosome was 99.3%, 99.7% and 99.7%, respectively (P>0.05). In fresh cases (Day 4 to Day 5/6 culture), the concordance rate for whole chromosome copy number per sample between NIPGS vs. TE samples taken from the same embryo was 100%, and the rate of concordance per single chromosome was 98.2% (P>0.05). CONCLUSIONS:A combination of BCCM and BF contains sufficient embryonic DNA for whole genome amplification and accurate aneuploidy screening. Our findings suggest that aneuploidy screening using BCCM combined with BF could potentially serve as a novel NIPGS approach for use in human IVF

Russia’s Economic Interests in the Realization of Perspective Infrastructure Projects in Energetics in East Asia

Purpose. The purpose of the article is feasibility study of transformation’s mechanisms of management of Russian fuel and energy complex (FEC) for elimination of risks and threats to national economic interests for our country, which were manifested in the period of falling oil prices and the introduction of anti-Russian economic and political sanctions.Methodology. In this article were used general scientific and special methods, including methods of system and economic analysis. Using the analytical methodology, there were investigated the main components of the protection of economic interests of Russia, during realization of perspective infrastructure projects in energetics in East Asia in the circumstances of critical economic and financial instability.Results. It is substantiated the expedience and the basic steps for creating an Asian energetic grid as a promising infrastructure project in energetics aimed at global redistribution of value added on the basis of energy supply by Russia of the cluster of key East Asian countries. It is proved that the concept of formation of an Asian energetic grid must be based on the strategic role of Russia as the guarantor of the energy security of the cluster of key East Asian countries, through the supply of a package of key Russian fuel and energy resources (electricity, gas, oil, coal, etc.). This will allow for a significant increase in mutual trade through integration of energetic systems of Russia, China, South Korea and Japan.Conclusions. There are suggested approaches to the justification of the ways of protecting the economic interests of our country in respect of the FEC of Russia, including: national concentration of management of energy resources’ export flows (delivery distribution, volumes of extraction, transportation, terms of payment, etc.); intercorporate coordination of measures on development, reconstruction and modernization of fuel and energy infrastructure; formation of qualitatively new infrastructure of the wholesale and retail markets of fuel and energy resources (FER); go to create overseas mechanism of energy hub management in respect of the supply and transportation of Russian energy resources; refinement of measures of coordination and work of the profit centers, corporate financial centers, centers of concentration of property’s ownership and financial assets and management for major energy corporations of Russia, including their subsidiaries and affiliates abroad, etc.Sphere of application. The technology in question is offered as an integral part of the technology of management of sectors of the Russian economy with regard to possible economic fluctuations in the global economy in the circumstances of significant changes associated with the new political realities in the US, EU, etc

Non-invasive and invasive preimplantation genetic testing workflow.

<p>Non-invasive and invasive preimplantation genetic testing workflow.</p

Concordance of blastocyst ploidy and karyotype per sample and per chromosome assessed by NIPGS vs TE vs WB.

<p>Concordance of blastocyst ploidy and karyotype per sample and per chromosome assessed by NIPGS vs TE vs WB.</p

Summary of NGS results from NIPGS and TE samples obtained from the same blastocyst in fresh cases.

<p>Summary of NGS results from NIPGS and TE samples obtained from the same blastocyst in fresh cases.</p

Three examples comparing TE biopsy, NIPGS and WB from the same vitrified-thawed embryo.

<p>Fig 2A, 2B and 2C show consistent results between TE biopsy, NIPGS and WB samples. Size of segmental loss detected in 2C was smaller in the WB sample compared with the TE and NIPGS samples (37.15 Mb vs. 53.69 Mb).</p