Baseline characteristics of patients on hospital admission (n = 2390).

<p>Baseline characteristics of patients on hospital admission (n = 2390).</p

Patient flow chart.

<p>Patient flow chart.</p

Data is presented as mean values with IQRs.

<p>Statistical testing shows group comparison of patients with hypophosphatemia (n = 480) and hyperphosphatemia (n = 215) versus patients with serum phosphate within the normal range (n = 1695) (Mann-Whitney U, p<0.05*).</p><p>Data is presented as mean values with IQRs.</p

Multivariate Cox regression analysis for mortality in patients with with hypophosphatemia.

<p>(p<0.05*), data presented in odds ratios (OR) with 95% confidence intervals (95% CI).</p><p>Multivariate Cox regression analysis for mortality in patients with with hypophosphatemia.</p

Multivariate Cox regression analysis for mortality in patients with hyperphosphatemia (A) and patients with hypophosphatemia (B).

<p>(p<0.05*), data presented in odds ratios (OR) with 95% confidence intervals (95% CI).</p><p>Multivariate Cox regression analysis for mortality in patients with hyperphosphatemia (A) and patients with hypophosphatemia (B).</p

Associations of phosphate levels with different parameters in univariate analysis.

<p>Pearson’s Chi-Square Test (p<0.05*).</p><p>Associations of phosphate levels with different parameters in univariate analysis.</p

Kaplan-Meier curve for 28 day in-hospital mortality in patients with hyperphosphatemia (grey line) versus patients with hypophosphatemia (blue line) and patients with normal phosphate levels (green line) (p<0.001).

<p>Kaplan-Meier curve for 28 day in-hospital mortality in patients with hyperphosphatemia (grey line) versus patients with hypophosphatemia (blue line) and patients with normal phosphate levels (green line) (p<0.001).</p

MOESM1 of Acid–base status and its clinical implications in critically ill patients with cirrhosis, acute-on-chronic liver failure and without liver disease

Additional file 1: Figure S1. Acid–base disturbances and their relation to severity of disease in critically ill patients with and without liver cirrhosis. Overall following parameter differed significantly between cirrhosis and non-cirrhosis patients (Wilcoxon’s signed-rank test): BE (p < 0.01), lactate (p < 0.001), BEUMA (p < 0.05), SIG (p < 0.01) and PaCO2 (p < 0.01), but not pH (p = 0.624). *p values between regression slopes were obtained from linear regression models with interaction term

MOESM3 of Acid–base status and its clinical implications in critically ill patients with cirrhosis, acute-on-chronic liver failure and without liver disease

Additional file 3: Table S1

MOESM1 of Outcome and features of acute kidney injury complicating hypoxic hepatitis at the medical intensive care unit

Additional file 1. Supplementary Tables. Table S1. Major underlying conditions associated with occurrence of hypoxic hepatitis. Table S2. Underlying conditions in patients with and without hypoxic hepatitis at the time RRT was initiated. Table S3. SOFA score, organ failures and 28-day-mortality in HH patients requiring renal replacement therapy