1,557 research outputs found
Alien Registration- Vaillancourt, Marie J. (Lewiston, Androscoggin County)
https://digitalmaine.com/alien_docs/27023/thumbnail.jp
Placing Confidence Limits on Polarization Measurements
The determination of the true source polarization given a set of measurements
is complicated by the requirement that the polarization always be positive.
This positive bias also hinders construction of upper limits, uncertainties,
and confidence regions, especially at low signal-to-noise levels. We generate
the likelihood function for linear polarization measurements and use it to
create confidence regions and upper limits. This is accomplished by integrating
the likelihood function over the true polarization (parameter space), rather
than the measured polarization (data space). These regions are valid for both
low and high signal-to-noise measurements.Comment: 8 pages, 3 figures, 1 table, submitted to PAS
The Removal of Artificially Generated Polarization in SHARP Maps
We characterize the problem of artificial polarization for the Submillimeter
High Angular Resolution Polarimeter (SHARP) through the use of simulated data
and observations made at the Caltech Submillimeter Observatory (CSO). These
erroneous, artificial polarization signals are introduced into the data through
misalignments in the bolometer sub-arrays plus pointing drifts present during
the data-taking procedure. An algorithm is outlined here to address this
problem and correct for it, provided that one can measure the degree of the
sub-array misalignments and telescope pointing drifts. Tests involving
simulated sources of Gaussian intensity profile indicate that the level of
introduced artificial polarization is highly dependent upon the angular size of
the source. Despite this, the correction algorithm is effective at removing up
to 60% of the artificial polarization during these tests. The analysis of
Jupiter data taken in January 2006 and February 2007 indicates a mean
polarization of 1.44%+/-0.04% and 0.95%+/-0.09%, respectively. The application
of the correction algorithm yields mean reductions in the polarization of
approximately 0.15% and 0.03% for the 2006 and 2007 data sets, respectively.Comment: 19 pages, 7 figure
Cutter Assembly for Microscope and Related Method
A low-profile cutter assembly for use on a microscope and related cutting method are provided. The cutter assembly includes a support subassembly having a mounting ring for receiving and engaging the objective of a microscope. A cutter subassembly carried by the support subassembly is displaceable between a home and a forward position in response to actuation. Upon reaching the forward position, additional actuation causes the front end of the cutter subassembly to pivot toward the stage, thereby placing a cutter adjacent to or in contact with the specimen. By selectively actuating the cutter subassembly, multiple cuts may be performed, as necessary or desired for cutting a spore or isolating a particular specimen
Magnetic Field Structure around Low-Mass Class 0 Protostars: B335, L1527 and IC348-SMM2
We report new 350 micron polarization observations of the thermal dust
emission from the cores surrounding the low-mass, Class 0 YSOs L1527,
IC348-SMM2 and B335. We have inferred magnetic field directions from these
observations, and have used them together with results in the literature to
determine whether magnetically regulated core-collapse and star-formation
models are consistent with the observations. These models predict a pseudo-disk
with its symmetry axis aligned with the core magnetic field. The models also
predict a magnetic field pinch structure on a scale less than or comparable to
the infall radii for these sources. In addition, if the core magnetic field
aligns (or nearly aligns) the core rotation axis with the magnetic field before
core collapse, then the models predict the alignment (or near alignment) of the
overall pinch field structure with the bipolar outflows in these sources. We
show that if one includes the distorting effects of bipolar outflows on
magnetic fields, then in general the observational results for L1527 and
IC348-SMM2 are consistent with these magnetically regulated models. We can say
the same for B335 only if we assume the distorting effects of the bipolar
outflow on the magnetic fields within the B335 core are much greater than for
L1527 and IC348-SMM2. We show that the energy densities of the outflows in all
three sources are large enough to distort the magnetic fields predicted by
magnetically regulated models.Comment: Accepted for publication in The Astrophysical Journa
Relative efficiency of split-marker versus double-crossover replacement protocols for production of deletion mutants in strain PH-1 of Fusarium graminearum
The split-marker (SM) protocol has become a popular method for production of knockout mutations in fungi. We used Southern hybridization to compare the performance and efficiency of the SM protocol with the more traditional double-crossover intact marker (IM) method for creating deletions of the mating type genes in Fusarium graminearum. Both methods successfully produced knockouts at a rate of between 24 and 75%: the SM method produced mutants more efficiently for larger constructs (\u3e1 kb), but it was similar to IM for a smaller construct that was 865 bp. Both methods also produced strains with additional ectopic integrations at a similar rate of approximately 10%, but on average the SM produced a higher number of independent integrations in those strains. Ectopic integrations produce off-site mutations, and strains with multiple integrations are less desirable since it is more difficult to remove them by backcrossing. Southern hybridizations will be generally superior to PCR to identify strains with fewer ectopic integrations for experimental purposes
The 2013 cholesterol guideline controversy: Would better evidence prevent pharmaceuticalization?
AbstractCardiovascular disease (CVD) remains the leading cause of death globally. A class of medications, known as statins, lowers low-density lipoprotein cholesterol levels, which are associated with CVD. The newest 2013 U.S. cholesterol guideline contains an assessment of risk that greatly expands the number of individuals without CVD for whom statins are recommended. Other countries are also moving in this direction. This article examines the controversy surrounding these guidelines using the 2013 cholesterol guidelines as a case study of broader trends in clinical guidelines to use a narrow evidence base, expand the boundaries of disease and overemphasize pharmaceutical treatment.We find that the recommendation in the 2013 cholesterol guidelines to initiate statins in individuals with a lower risk of CVD is controversial and there is much disagreement on whether there is evidence for the guideline change. We note that, in general, clinical guidelines may use evidence that has a number of biases, are subject to conflicts of interest at multiple levels, and often do not include unpublished research. Further, guidelines may contribute to the “medicalization” or “pharmaceuticalization” of healthcare.Specific policy recommendations to improve clinical guidelines are indicated: these include improving the evidence base, establishing a public registry of all results, including unpublished ones, and freeing the research process from pharmaceutical sector control
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