18 research outputs found
MATERIALS SCIENCE BEAMLINE, ELETTRA TRIESTE - NEW INSTRUMENT FOR SURFACE SCIENCE
The Materials Science Beamline is attached to a bending magnet at synchrotron Elettra Trieste, Italy. The tuning range is from 35 to 800 eV with calculated spectral resolving power E/delta E better than 4000 in the whole range. The optical elements consist of a toroidal prefocusing mirror, polarization aperture, entrance slit, plane pre-mirror, single plane grating (blazed), spherical mirror, exit slit and toroidal refocusing mirror. The plane grating is operated in the fixed focus mode with Cff = 2.4. Energy scanning is performed by rotation of the plane grating and simultaneous translation and rotation of the plane pre-mirror. In the first tests, a resolving power of at least 4000 has been achieved at energies of 400 eV. The calculated photon flux at the sample is compared with measured values. Various experimental chambers depending on experiments can be attached to the beamline (LEEM, ESCA)
Aggressive systemische Mastozytose mit erhöhter diffuser 18F-FDG-Aufnahme im Knochenmark [Aggressive systemic mastocytosis with diffuse bone marrow 18F-FDG uptake]
Mastocytosis is a clonal hematopoietic disorder characterized by proliferation of abnormal mast cells in various organs including the skin, digestive system, lymph nodes, and bone marrow. We report on a 75-year-old woman presenting with abdominal pain, vomiting, diarrhoea, myalgia, and weight loss. Abdominal CT showed hepatosplenomegaly with heterogeneous splenic parenchyma, lymphadenopathy, and osteopenia with areas of osteosclerosis but no primary tumour. An <sup>18</sup> F-FDG PET/CT revealed an overall low metabolic activity of the lesions with a diffuse bone marrow involvement raising suspicion of a haematological neoplasm. Subsequently, bone marrow and peripheral blood examinations confirmed the diagnosis of aggressive systemic mastocytosis
18F-FDG PET/CT pattern of Erdheim-Chester disease – a group of Czech patients
Introduction: Erdheim-Chester disease (ECD) is a rare unit of histiocytic diseases. The goal of our work was to assess 18F-FDG PET/CT presentation of this disease in patients from the Czech Republic.
Methods: We analyzed overall 44 18F-FDG PET/CT examinations in 6 patients with this disease. We assessed 18F-FDG accumulation in staging examinations of these 6 patients at usual localizations, i.e. bones, brain, orbit, paranasal sinuses, periaortal space, heart, lungs, perirenal space and skin.
Results: Bone 18F-FDG accumulation was detected in all patients; in 5 mostly in lower extremities. Maxillar sinuses were involved in 5/6 patients. Vascular and perirenal involvement
was detected in 4/6 patients. Two patients had involved skin and hypophysis, one patient also orbits and heart. Lung involvement was not detected in any patient.
Conclusions: 18F-FDG avid involvement of skeleton was the main and regular characteristic of PET/CT presentation of Erdheim-Chester disease. Also other localizations of
18F-FDG avid involvement (cardiovascular, CNS, paranasal sinuses, orbitis, skin, perirenal space) confirm known observations in ECD.