Segregação de Resíduos Químicos por Compatibilidade e Reatividade no Instituto Butantan

O Plano de gerenciamento de resíduos químicos no Instituto Butantan utiliza uma combinação de critérios que devem ser avaliados ao se trabalhar com esses resíduos: a incompatibilidade inter e intra classes, a reatividade química e caraterísticas que podem interferir na classificação de risco de determinadas substâncias, como a hidratação e a concentração. Esse programa também apresenta atividades educacionais, medidas de minimização de geração de resíduos e ainda conta com um químico como responsável técnico. De forma integrada a engenharia de segurança, destinou os resíduos químicos de forma segura e atendendo a legislação. Esse plano minimiza os riscos operacionais e pode ser usado não apenas para a segregação de resíduos químicos, mas também no acondicionamento de produtos químicos em laboratórios e indústrias, contribuindo para o desempenho seguro das atividades nos diferentes setores, bem como para promoção do bem estar da sociedade. DOI: http://dx.doi.org/10.17807/orbital.v7i1.68

Report of the Topical Group on Dark Energy and Cosmic Acceleration: Complementarity of Probes and New Facilities for Snowmass 2021

The mechanism(s) driving the early- and late-time accelerated expansion of the Universe represent one of the most compelling mysteries in fundamental physics today. The path to understanding the causes of early- and late-time acceleration depends on fully leveraging ongoing surveys, developing and demonstrating new technologies, and constructing and operating new instruments. This report presents a multi-faceted vision for the cosmic survey program in the 2030s and beyond that derives from these considerations. Cosmic surveys address a wide range of fundamental physics questions, and are thus a unique and powerful component of the HEP experimental portfolio.Comment: Submitted to the Proceedings of the US Community Study on the Future of Particle Physics (Snowmass 2021); Topical Group Report for CF06 (Cosmic Frontier Topical Group on Dark Energy and Cosmic Acceleration: Complementarity of Probes and New Facilitie

Imaging techniques and histology in the evaluation of liver fibrosis in hepatosplenic schistosomiasis mansoni in Brazil: a comparative study

Few publications have compared ultrasound (US) to histology in diagnosing schistosomiasis-induced liver fibrosis (LF); none has used magnetic resonance (MR). The aim of this study was to evaluate schistosomal LF using these three methods. Fourteen patients with hepatosplenic schistosomiasis admitted to hospital for surgical treatment of variceal bleeding were investigated. They were submitted to upper digestive endoscopy, US, MR and wedge liver biopsy. The World Health Organization protocol for US in schistosomiasis was used. Hepatic fibrosis was classified as absent, slight, moderate or intense. Histology and MR confirmed Symmers' fibrosis in all cases. US failed to detect it in one patient. Moderate agreement was found comparing US to MR; poor agreement was found when US or MR were compared to histology. Re-classifying LF as only slight or intense created moderate agreement between imaging techniques and histology. Histomorphometry did not separate slight from intense LF. Two patients with advanced hepatosplenic schistosomiasis presented slight LF. Our data suggest that the presence of the characteristic periportal fibrosis, diagnosed by US, MR or histology, associated with a sign of portal hypertension, defines the severity of the disease. We conclude that imaging techniques are reliable to define the presence of LF but fail in grading its intensity