151 research outputs found
Reavaliando o lugar das psicoses ciclóides: a propósito de um caso clínico
Introdução: O conceito de psicose ciclóide foi
descrito pela primeira vez por Karl Kleist. Mais
tarde, Leonhard propôs a corrente conceptualização descrevendo três subtipos da doença
e Perris desenvolveu os primeiros critérios
diagnósticos operacionais. O diagnóstico de
psicose ciclóide possui uma longa tradição na
psiquiatria europeia, mas o conceito ciclóide
não está explicitamente patente nos esquemas
internacionais de diagnóstico (DSM 5 e ICD-10) suscitando um debate controverso quanto
à sua utilidade e validade.
Objetivos: O presente artigo pretende, a partir
de um caso clínico, abordar o conceito de psicose ciclóide enfatizando a sua importância à
luz da psiquiatria atual, discutindo o uso do
conceito e a sua validade clínica e preditiva.
Métodos: Os autores apresentam um caso clínico de psicose recorrente com total remissão
interepisódica e afetação funcional mínima.
Resultados e Discussão: O artigo ilustra a
importância de estarmos atentos ao diagnóstico de psicose ciclóide dado o seu prognóstico e
tratamento distinto das restantes psicoses.
Conclusão: Enquanto esta perturbação, de
incidência desconhecida, não for devidamente
explorada, mais investigação será necessária
dado o seu prognóstico favorável e a sua patofisiologia e tratamento potencialmente distintos
Liquid–liquid equilibrium of the Ucon 50-HB5100/sodium citrate aqueous two-phase systems
The phase diagrams of Ucon 50-HB5100/sodium citrate aqueous two-phase systems were determined at 5, 20 and 40 ◦C. Two medium pHs
5.20 and 8.20 were assayed. The binodal curves were satisfactorily described using a four-parameter sigmoidal equation. The two-phase area was
expanded by increasing both pH and temperature. The reliability of the measured tie line compositions was ascertained by correlation equations
given by Othmer–Tobias and Bancroft.VALNATURACONICETALFA II-0440-FA-Exchange programme between Universities
of the European Union and Latin Americ
Liquid-liquid equilibrium and partitioning features of bovine trypsin in Ucon 50 HB5100 /sodium citrate aqueous two phase systems
The phase diagrams of Ucon 50-HB-5100, a non-ionic random copolymer of ethylene oxide and propylene
oxide (EOPO) and sodium citrate aqueous two-phase systems were determined at different pHs (5.20
and 8.20) and temperatures (5, 20 and 40º C). The binodal curves were determined by refractive index and
enzymatic assay of the solution and described using a four-parameter sigmoidal equation, the reliability
of the measured tie line compositions was ascertained by correlation equations given by Othmer Tobias
and Bancroft. The two-phase area was expanded by increasing both pH and temperature. The partitioning
of bovine trypsin and a-chymotrypsin, proteases of similar physico-chemical properties was investigated
in order to evaluate the applicability of partitioning as a putative method to isolate from pancreas and to
obtain any information about their partitioning mechanism. The effect of different factors such as pH, tie
line length and the presence of an inorganic salt on the protein partition coefficient were analyzed.Se caracterizaron las curvas binomiales correspondientes a los sistemas bifásicos acuosos formados por
Ucon 50-HB-5100, un copolímero al azar de óxido de etileno y óxido de propileno (EOPO) y citrato de
sodio a diferentes pHs (5,20 y 8,20) y temperaturas (5, 20 y 40º C). Las curvas binomiales se obtuvieron
por determinación del índice de refracción y ensayos enzimáticos de las soluciones correspondientes; las
composiciones de las líneas de unión se corroboraron por las ecuaciones propuestas por Othmer Tobias y
Bancroft. El aumento del pH y la temperatura condujeron a un aumento del área bifásica. También se
ensayó el comportamiento de reparto de dos proteasas tripsina y α-quimotripsina con el objetivo de
emplear los principios de partición como método de aislamiento y purificación de Tripsina a partir de páncreas
bovino y de obtener información acerca del mecanismo de partición de la misma. Se analizó el efecto
del pH, longitud de la línea de unión y presencia de sales inorgánicas sobre el coeficiente de partición
de las enzimas
Distribuição das formas de fósforo após 15 anos da adoção de sistemas de manejo.
Editado por: Clenio Nailto Pillon, Deborah Pinheiro Dick, Ladislau Martin Neto; Trabalho publicado também em Resumos do NCONTRO BRASILEIRO DE SUBSTÂNCIAS HÚMICAS, 8., 2009, Pelotas
Fungi in bottled water: a case study of a production plant
A one year fungal survey of a water bottling plant was conducted in order to
evaluate the incidence and fluctuations of the biota. The dominant fungal genera
in order of highest numbers were Penicillium, Cladosporium and Trichoderma
followed by Aspergillus, Paecilomyces, and others. As expected, highest number of
isolates collected were during the summer months, particularly May and June.
Indeed during these two months there were more fungi present in the water after
it had passed through the filtration system (0.4μm filter), indicating that during
those times of the year when fungal contamination is high, filters should be
changed on a more regular basis. In order to assess whether contamination was
single or multi-loci, molecular methods based on PCR were used. Overall fungal
contamination arose from multiple sources. Some fungal strains were very “alike”
and were detected during different sampling times, indicating that some strains
were endemic to the plant. There was little evidence to suggest that fungi
detected in the source water passed through to other parts of the plant. However,
there was evidence that fungal strains isolated from the water filter were detected
elsewhere in the factory, confirming the need to change filters more regularly
during periods of high fungal contamination. In order to improve quality control a
HACCP programme was implemented and Best Practice Guidelines introduced.Control of Mycological Contaminations in Bottled Water (COMBOW) -
CRAFT/QLK1-2002-70843 contract
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