2,894 research outputs found
Fermentation of Low Grade Glycerol by Clostridium butyricum and Clostridum acetobutyllcum Strains
Diretório Nacional de pesquisadores de trigo.
Tecnicos; Indice de autor; Indice por area de atuacao; Indice geografico.bitstream/item/65907/1/CPAO-DOC.-48-91.pd
Therapeutic Approach to Parapneumonic Effusions and Empyemas
Face à inexistência de uma metodologia única e consensual na abordagem terapêutica dos derrames pleurais parapneumónicos e empiemas, os autores propõem um protocolo de orientação, que
resultou da reflexão baseada na sua experiência e na bibliografia mais recente
From Clinical Presentation to the Outcome: the Natural History of PML in a Portuguese Population of HIV Infected Patients
Background
Progressive multifocal leukoencephalopathy (PML) is a demyelinating disease of the central nervous system, associated with immunosuppression states. As there are only some non-published documents concerning PML in HIV infected patients in Portugal, we pretend to characterize natural history of PML infection in a population of HIV patients.
Methods
We retrospectively reviewed, from 1992 to 2009, PML cases in a population of 724 HIV infected patients followed in our institution. Clinical, biological, imagery features and outcomes were characterized.
Results
Twenty-five (3.45%) patients were identified as having PML. The mean time between HIV and PML diagnosis was 20.4 months. PML was the presentation of HIV infection in 40% of the patients, and 92% had CD4 T cell count lower than 200/mm3. Paresis was the most common clinical presentation. No specific characteristics were found in cerebrospinal fluid and JCV DNA was positive in 3 of 7 patients. MRI revealed characteristic findings. Combined antiretroviral therapy was started or changed in 96% of the patients. Neurological condition got worse in 12 patients. From the 14 deaths, 5 were directly attributed to PML progression. Follow-up was lost in 8 patients.
Conclusions
PML was the presentation of HIV infection in more than 1/3 of patients, frequently associated with advanced immunocompromise. MRI sensitivity to PML is high, and JCV DNA determination in CSF was not revealed to be sensible. PML diagnosis should be taken into account in HIV patients presenting any neurological symptoms, and HIV infection should be suspected when radiological findings suggest PML lesions even in previously healthy individuals
Production of 1,3-propanediol by Clostridium butyricum VPI 3266 using a synthetic medium and raw glycerol
Growth inhibition of Clostridium butyricum
VPI 3266 by raw glycerol, obtained from the biodiesel
production process, was evaluated. C. butyricum presents
the same tolerance to raw and to commercial
glycerol, when both are of similar grade, i.e. above 87%
(w/v). A 39% increase of growth inhibition was observed
in the presence of 100 g l 1 of a lower grade raw
glycerol (65% w/v). Furthermore, 1,3-propanediol production
from two raw glycerol types (65% w/v and 92%
w/v), without any prior purification, was observed in
batch and continuous cultures, on a synthetic medium.
No significant differences were found in C. butyricum
fermentation patterns on raw and commercial glycerol
as the sole carbon source. In every case, 1,3-propanediol
yield was around 0.60 mol/mol glycerol consumed
Avaliação do efeito de níveis de calcário no desenvolvimento e na absorção de nutrientes, em plantas de heliconia (Golden torch).
Pseudomonas koreensis A9 genome insights in heterotrophic sulfide oxidation
info:eu-repo/semantics/publishedVersio
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