12,501 research outputs found

    Analyzing Disproportionate Reaction via Comparative Multilingual Targeted Sentiment in Twitter

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    Global events such as terrorist attacks are commented upon in social media, such as Twitter, in different languages and from different parts of the world. Most prior studies have focused on monolingual sentiment analysis, and therefore excluded an extensive proportion of the Twitter userbase. In this paper, we perform a multilingual comparative sentiment analysis study on the terrorist attack in Paris, during November 2015. In particular, we look at targeted sentiment, investigating opinions on specific entities, not simply the general sentiment of each tweet. Given the potentially inflammatory and polarizing effect that these types of tweets may have on attitudes, we examine the sentiments expressed about different targets and explore whether disproportionate reaction was expressed about such targets across different languages. Specifically, we assess whether the sentiment for French speaking Twitter users during the Paris attack differs from English-speaking ones. We identify disproportionately negative attitudes in the English dataset over the French one towards some entities and, via a crowdsourcing experiment, illustrate that this also extends to forming an annotator bias

    Neisseria gonorrhoeae challenge increases matrix metalloproteinase-8 expression in fallopian tube explants

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    Indexación: Scopus.Background: Neisseria gonorrhoeae (Ngo) is the etiological agent of gonorrhea, a sexually transmitted infection that initially infects the female lower genital tract. In untreated women, the bacteria can ascend to the upper genital reproductive tract and infect the fallopian tube (FTs), which is associated with salpingitis and can lead to impaired FT function and infertility. The extracellular matrix (ECM) plays an important role in cell migration and differentiation in the female genital tract, and some pathogens modify the ECM to establish successful infections. The ECM is regulated by matrix metalloproteinases (MMPs) and tissue inhibitors of metalloproteinases (TIMPs), their endogenous inhibitors; MMP deregulation causes pathological conditions in a variety of tissues. Results: The aim of this work was to analyze the expression and localization of MMP-3, MMP-8, MMP-9, and TIMP-1 in FT explants during Ngo infection using real-time PCR, immunohistochemistry, zymography and ELISA. No significant variations in MMP-3, MMP-9, and TIMP-1 transcript levels were observed. In contrast, a significant increase (p < 0.05) was observed for MMP-8 expression and was accompanied by stromal immunoreactivity in infected explants. ELISA results supported these findings and showed that MMP-8 release increased upon gonococcal infection. Conclusions: Our results indicate that gonococcal infection induces increased MMP-8 expression, which might contribute to FT damage during infection. © 2017 Juica, Rodas, Solar, Borda, Vargas, Muñoz, Paredes, Christodoulides and Velasquez.https://www.frontiersin.org/articles/10.3389/fcimb.2017.00399/ful

    Datos estructurales sobre el anticlinal de "San Emiliano-Valgrande" y unidades periféricas (Cordillera Cantábrica)

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    Se mencionan algunos datos estructurales sobre el anticlinal mecanizado que se extiende, desde las proximidades de San Emiliano (León) hasta el nacimiento del río Valgrande (Asturias), el cual, resulta ser una muy destacada estructura de replegamiento de la Unidad Cabalgante de Pajares. Se citan algunas otras observaciones sobre el carácter, en estazona, de la Unidad Cabalgante de Villamanín, que se le superpone, adquiriendo aquí una notable complejidad en la zona frontal, definiendo una serie de escamas y, conjuntamente, una semiventana tectónica de cierta importancia

    Reconocimiento de señales de deformación en pudingas de la Cuenca Carbonífera Central de Asturias

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    Se describe la existencia de señales de deformación (impresiones cóncavas, torsiones y fracturas) de nexo tectónico en cantos de pudingas cuarcíticas del Carbonífero (Westfaliense C-D, probablemente) de la Cuenca Central de Asturias (España)
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