Isolated adrenal metastases of papillary thyroid carcinoma

Funding Information: The authors thank the Pathology Department of Instituto Portugu?s de Oncologia de Lisboa Francisco Gentil for providing representative images of the histological slides.publishersversionpublishe

Effectiveness of the flipped classroom methodology In the performance of higher education students: systematic review with meta-analysis

Introduction: The methodology Flipped Classroom (FC) consists in individual activities that the student has to do at home through the use of technologies which help the student to prepare for class, and during classes, activities are performed as more dynamic classes centered on the student. Through the years, the success has reached the maximum levels of performance and satisfaction in the teaching sessions in different areas of education compared to the classical methods, and there are no conclusive and considerable studies that compile and analyze this information succinctly. Objective: To analyze experimental and quasi-experimental studies that evaluate the methodology database in FC in performance and student satisfaction in comparison with the expository methodology. Methodology: This article is a systematic review that analyzes the randomized controlled trial (RCT) and Quasi-experimental studies selected with the methodology FC, which measures the efficacy through the results achieved in the realization and evaluation of the students. These articles were found in EBSCOhost and PubMed. Results: We selected 41 articles, that fulfilled all inclusion criteria established by the authors, for the accomplishment of this systematic review. Discussion: The results of our meta-analysis, both RCTs and quasi-experimental studies, point to a better effectiveness of the FC methodology compared to the expository methodology in academic performance. However, there is a heterogeneity in planned and developed activities during class, which means that our conclusions can’t be generalized. The poor methodological quality of the included studies, especially quasi-experimental studies, does not allow our conclusions about efficacy to be vigorous. Nevertheless, based on these first promising data, it seems to us that this methodology offers learning opportunities that aren’t possible in a classroom based on lectures and subject matter exposition. Conclusion: Although the articles selected have poor methodological quality, and it is necessary more rigorous investigations on this methodology, we believe that the FC methodology could revolutionize teaching methods and replace traditional teaching, which is so deeply rooted in today's society and doesn’t seems to favor the achievement of transversal competences.info:eu-repo/semantics/publishedVersio

GROUND VALIDATION OF SATELLITE-BASED PRECIPITATION FOR FLOOD SIMULATION IN SOUTH-EAST ASIAN RIVER BASINS

ABSTRACT Flood simulation at basin scale can be enhanced by combining Satellite-Based Precipitation (SBP) with ground rain gauge measurements. The present study attempts to show feasible approaches in terms of time, space and pattern at selected basins in South East Asia. As for temporal downscaling it was possible to detect flood timing and magnitude with high temporal resolution at poorly gauged basins. This approach was tested at the upper part of the Huong in Vietnam and Ping River basins in Thailand respectively. Both catchments are located in steep, humid, and vegetated areas. Two SBPs were employed: the Global Satellite Mapping of Precipitation (GSMaP) MVK version and the Tropical Rainfall Measuring Mission (TRMM) 3B42 Ver. 6product. The results indicate that SBPs products tend to underestimate precipitation intensities, but they seem able to depict the spatial and temporal patterns. The evaluated SBPs at basin scale were found useful and river discharge simulation was enhanced with corrected SBPs. This approach might be applied at other basins not only in Asia region

Profile of Salinity, Temperature, Heavy Metal (Pb, Cd, Hg) and Sediment Hydrogen Sulfide Concentration of Manila Bay, Philippines from 2012 to 2015

The physical parameters of seawater are important determinants of water quality. Heavy metals are components that are naturally present in a considerable amount in the ocean but are observed to be rising above the allowable level due to pollution outputs of industrialization. Heavy metal contamination is among the environmental pollution problems that the world faces. Additionally, hydrogen sulfide (H2S) is also a toxic compound that accumulates in the ocean floor posing threat to the marine organisms when present in high concentrations. The objective of this study is to document the distribution of temperature and salinity in the water column, heavy metals (Pb, Cd, Hg) and sediment H2S in Manila Bay from 2012 to 2015. Stratification in the bay was generally a factor of salinity and less of temperature. Stratification due to salinity was consistently observed in September with the halocline occurring around 10 m to 15 m. Most of the time, the bay had evenly distributed temperatures, but the slightly higher temperatures were usually recorded near the coast. Inverse trends were observed for the salinity and temperature of the bay. Pb, Cd, and Hg concentrations in the bay occasionally exceeded the permissible limits especially the lead concentration in January 2013 (ave: 809.81 µg/L), March 2013 (ave: 1102.88 µg/L) and November 2015 (1507.50 µg/L). Cd and Hg concentrations were generally below the permissible limit and the reported limit of analysis. H2S concentration ranged from < 4 mg/kg to 9.99 mg/kg for all the survey months. Distribution was higher in the northwestern part and southeastern areas of the bay