Морфолого-анатомическое изучение свежих и высушенных плодов и семян свидины белой (Swida alba (L.) Opiz.) как возможных источников жирного масла

We have studied ripe and dry fruit and seeds of Swida alba (L.) Opiz., cultivated in Moscow and Moscow province. We have proposed morphological and anatomical signs of Swida alba (L.) Opiz. ripe and dry fruit and seeds for raw material quality control.Авторами статьи проведено морфолого-анатомическое исследование плодов свидины белой, культивируемой в Москве и Московской области. Впервые выявлены диагностические признаки в анатомическом строении свежих и высушенных плодов свидины белой, которые могут быть рекомендованы для установления подлинности плодов методом микроскопии и контроля качества этого нового перспективного сырья

Морфолого-анатомическое изучение свежих и высушенных плодов и семян бузины черной (Sambucus nigra L.) как возможных источников пищевых и лекарственных веществ

We have studied ripe and dry fruit and seeds of Sambucus nigra L. from Nalchik province. We have proposed morphological and anatomical description of ripe and dry fruit and seeds of Sambucus nigra L. for raw material quality control.Авторами статьи проведено морфолого-анатомическое исследование плодов бузины черной, собранных в пригороде г. Нальчик в пойме реки Черек. Впервые дано морфолого-анатомическое описание свежих и высушенных плодов и семян бузины черной для установления подлинности растительного сырья

Genetic and epigenetic changes of NKIRAS1 gene in human renal cell carcinomas

Renal cell carcinoma (RCC) is the most common malignant tumor of kidney associated with the worst clinical outcome. No molecular markers for RCC diagnostics and prognosis that could be applied in clinics were described yet. Large-scale screening of 3p human chromosome genes/loci in RCC and histologically normal tissues surrounding the tumors using NotI-microarray approach demonstrated that NKIRAS1 gene contained the largest percent of genetic/epigenetic changes in RCC tumor cells. Aim: To validate the results of NotI microarray analysis and study genetic, epigenetic changes, and the expression level of NKIRAS1 gene in human RCC samples. Methods: DNA and RNA were isolated from freshly-frozen renal tumors’ samples (n = 12) and from normal tissues surrounding the tumors. Epigenetic changes (methylation status) of NKIRAS1 were detected by bisulfite sequencing. Genetic changes and expression level were analyzed by Quantitative real-time PCR (qPCR) with SYBR Green. For relative quantification 2-ΔΔCP method was used. Nonparametric tests (Wilcoxon, Kruskal — Wallis and Mann — Whitney) were applied for statistical data analysis using the BioStat software. Results: NKIRAS1 expression was downregulated in 75% of RCC samples (9 of 12) compared with surrounding normal tissue. High grade tumors (3 and 4) showed lower expression of NKIRAS1 at the mRNA level than tumors of low grade (1 and 2). No significant association was found between gene expression level and gender or age. Analysis of NKIRAS1 gene copy number was performed in 19 tumor samples. Changes in the copy number of NKIRAS1 gene were observed in 64% (9 of 14) of cRCC samples. 9 samples displayed ratio ( 0.85) and were considered as normal copy number. Changes in NKIRAS1 gene copy number were detected in all 3 benign oncocytomas, 1 papillary cancer and 1 sarcoma, where hemizygous deletion was observed. No changes in methylation status of NKIRAS1 were found in RCC. Conclusions: We have validated the results of NotI microarray analysis of NKIRAS1 gene in RCC. It was shown the decreased expression level of NKIRAS1 in this type of tumor

The population history of northeastern Siberia since the Pleistocene

FGW – Publications without University Leiden contractDescriptive and Comparative Linguistic

Carboniferous and Permian Rugosochonetidae (Brachiopoda) from West Spitsbergen

The rugosochonetid brachiopod species Lissochonetes geinitzianus from the Kazimovian of the Nordenskioldbreen Formation, and Dyoros (Dyoros) mucronata sp. nov., Dyoros (Dyoros) spitzbergianus and Lissochonetes superba from the Artinskian to latest Permian Kapp Starostin Formation in West Spitsbergen are described and figured. Dyoros is generally restricted to the Boreal Realm, whereas Lissochonetes is mostly distributed in the Boreal Realm, but occasionally present in the Palaeoequatorial and Gondwanan Realms<br /

Modern theories of social anxiety in childhood and adolescence ages

This article describes the various modern approaches to the study of social anxiety in children. Social anxiety is examined in terms of the following approaches: in age-related psychology from the standpoint of behavioral inhibition and its biological sources; in developmental psychology as an affective-behavioral profile of loneliness/isolation and its sources in the child-parent relationship and interaction with peers; in clinical psychology within the Avoidant Personality Disorder (social phobia), its diagnosis, treatment and etiology. The article presents the results of current and future possible research

OUTPATIENT REHABILITATION OF CHILDREN WITH HEALTH DEVIATIONS

Outpatient help to underage population is leading priority for the general healthcare system. The main task of a child policlinic is prevention and early detection of pathologies, and decreasing of rates of illness and child mortality. Complex rehabilitation of children helps improve basic health indexes in underage population. The article displays effectiveness of complex program of medical and social rehabilitation of children with health deviations on the outpatient basis.Key words: medical and social rehabilitation, reflex therapy, child, sickness rate. (Voprosy sovremennoi pediatrii — Current Pediatrics. — 2011; 10 (6): 14–19.

Aristarchus Lewkowski — the founder of Saratov's Neurology (the 150th anniversary of his birth)

The article presents the information about the life, career and scientific work of Aristarchus Lewkowski — the founder of Saratov'sNeurological science school and the creator of outpatient neurological services