Magnetic field and unstable accretion during AM Herculis low states

A study of AM Her low states in September 1990 and 1991 and June-July 1997 is reported from a coordinated campaign with observations obtained at the Haute-Provence observatory, at the 6-m telescope of the Special Astrophysical Observatory and at the 2.6m and 1.25m telescopes of the Crimean observatory. Spectra obtained at different dates when the source was in low states at a comparable V magnitude, show the presence of strong Zeeman absorption features and marked changes in emission lines with a day-to-day reappearance of the HeII (4686\AA) emission lines in 1991. Despite this variability, the magnetic field inferred from the fitting of the absorption spectrum with Zeeman hydrogen splitting, is remarkably constant with a best value of (12.5$\pm$0.5)MG. Detailed analysis of the UBVRI light curves shows the presence of repetitive moderate amplitude ($\sim$ 0.3-0.5 mag) flares predominantly red in colour. These flares are attributed to small accretion events and are compared to the large ($\sim$ 2 mag.) blue flare reported by Shakhovskoy et al. (1993). We suggest that the general flaring activity observed during the low states is generated by accretion events. The different characteristics of the flares (colour and polarization) are the results of different shock geometries depending on the net mass accretion flux.Comment: accepted in Astronomy & Astrophysics (Main Journal), 10 pages, 6 Figures, Late

Адаптация микрорастений сливы домашней (Prunus domestica) к условиям in vivo

The aim of the research was the possibility of using zeolite for the adaptation of micro plants of plum home variety Kazanskaya under in vivo conditions. The control was a substrate for experiments based on grassroots peat (manufactured by JSC “Udmurttorf”, Udmurt Republic, Russia). In the studied variants, zeolite (Tatarsko-Shatrashanskoe deposit, Republic of Tatarstan, Russia) was added to peat in 60, 90, and 120 g/l doses. Microplants were also planted on a 100% zeolite substrate. It has been established that the survival rate of domestic plum micro plants to non-sterile conditions in a grassroots peat substrate with the addition of zeolite in all doses is significantly higher than in the control variant (78.3%) and varies within 86.7–99.2%. The survival rate of domestic plum micro plants in a 100% zeolite substrate was 80.8% at the control indicator’s level. At the first stage of adaptation, the growth length of micro plants in the bottom peat substrate with the addition of zeolite at doses of 60 and 90 g/l increased significantly. It amounted to 1.9 and 3.3 cm, respectively, with 1.2 cm in control. Compared with the maximum allowable duration of adaptation according to GOST R 54051-2010 of 45 days, the transformation of home plum was 21 days in general. At the same time, in the variants with the addition of zeolite to the substrate based on grassroots peat at doses of 60: 90 and 120 g/l, the growth length of home plum micro plants was, on average, 6.0, 8.0, and 5.3 cm, respectively, and the height of adapted micro plants to the end of the second stage of adaptation were 7.0; 9.0; 7.3 cm, which exceeded the performance of State Standard (SS) R 54051-2010.Целью исследований являлась возможность применения цеолита для адаптации микрорастений сливы домашней сорта Казанская в условиях in vivо. Для экспериментов контрольным был субстрат на основе низового торфа (изготовитель АО «Удмуртторф», Удмуртская Республика, Россия). В исследуемых вариантах в торф добавляли цеолит (Татарско-Шатрашанское месторождение, Республика Татарстан, Россия) в дозах 60; 90, 120 г/л. Микрорастения также высаживали на субстрат из 100% -го цеолита. Установлено, что приживаемость микрорастений сливы домашней к нестерильным условиям в субстрате из низового торфа с добавлением цеолита во всех дозах значительно выше, чем в контрольном варианте (78,3%), и варьирует в пределах 86,7–99,2%. Приживаемость микрорастений сливы домашней в 100%-м субстрате из цеолита составила 80,8%, что на уровне контрольного показателя. На первом этапе адаптации значительно увеличилась длина прироста микрорастений в субстрате из низового торфа с добавлением цеолита в дозах 60 и 90 г/л, она составила 1,9 и 3,3 см соответственно при 1,2 см в контроле. В сравнении с максимально допустимой длительностью адаптации по ГОСТ Р 54051-2010 в 45 суток адаптация сливы домашней в целом составила 21 сутки. При этом в вариантах с внесением в субстрат на основе низового торфа цеолита в дозах 60; 90 и 120 г/л длина прироста микрорастений сливы домашней в среднем оказалась 6,0; 8,0 и 5,3 см соответственно, а высота адаптированных микрорастений к концу второго этапа адаптации составила 7,0; 9,0; 7,3 см, что превысило показатели ГОСТ Р 54051-2010

Analysis of the incidence of tick-borne viral encephalitis in the Chkalovsky district of Yekaterinburg for the period 2012-2022

The purpose of the study is to study the epidemiological features of the incidence of tick–borne viral encephalitis in the territory of the Chkalovsky district of Yekaterinburg for the period 2012-2022.Цель исследования – изучить эпидемиологические особенности заболеваемости КВЭ на территории Чкаловского района г. Екатеринбурга за период 2012-2022 гг

Stent-assisted coiling of acute ruptured cerebral aneurysms

The necessity of quick surgical treatment of acute ruptured cerebral aneurysms was demonstrated in large studies by the ISAT and ISUIA, which also proved the advantage of the endovascular method over the surgical one. Ballonassistence is widely used in treatment of aneurysms with wide neck and unfavorable vascular anatomy, but the radicality of the treatment is insufficient. The aim of this study was to demonstrate the efficacy and safety of stent-assisted embolization of «acute» cerebral aneurysms. Material and methods. A retrospective analysis of the treatment of 234 patients with «acute» cerebral aneurysms was carried out. Results. Only coils were used in 40.6 % of cases (n = 95), balloon-assistance, in 40.2 % of cases (n = 94), and stent-assistance, in 19.2 % of cases (n = 45). There were 11.5 % (n = 27) clinically significant complications. Total aneurysm occlusion (Raymond-Roy I) was achieved in 187 cases (79.9 %); the radicality at the control examination was 67.1 % (157 patients). Discussion. The radicality of the treatment with stents was slightly higher then with balloons and coils at the end of operation (84.4 %, n = 38 and 78.8 %, n = 149, p > 0.05), but it was significantly higher at the control examination (80.0 %, n = 36 and 60.8 %, n = 115, respectively, p <0.05). Also, we had no statistically significant difference of the complication rate in the «stent» and «no stent» groups; therefore, the clinical outcomes of endovascular treatment of cerebral aneurysms did not depend on the choice of treatment method. Conclusions. Intracranial stents allow achieving good results of the embolization of complex aneurysms in the acute period of intracranial hemorrhage without increasing the risk of surgical treatment

СРАВНИТЕЛЬНЫЙ АНАЛИЗ ДВУХЭНЕРГЕТИЧЕСКОЙ РЕНТГЕНОВСКОЙ АБСОРБЦИОМЕТРИИ И БИОИМПЕДАНСОМЕТРИИ В ОЦЕНКЕ КОМПОНЕНТНОГО СОСТАВА ТЕЛА ПАЦИЕНТОВ НА ПРОГРАММНОМ ГЕМОДИАЛИЗЕ

The aim of the study. Compare the efficiency of the use of dual-energy x-ray absorptiometry (DRA) and bioimpedansometry (BIM) in the evaluation of the body composition of hemodialysis patients.Patients and methods. 67 patients on hemodialysis, among which 23 men and 44 women aged 54±14,4 years. BIM and DRA were used to evaluate the body composition.Results. The results of determining the total muscle mass of the body obtained by the results of DFA and BIM were compared with the use of the Bland-Altman method. The correlation coefficient between the indices was R=0,994, p<0,0001, delta (M±s) was –0,48±0,91 kg, CI 95% (–0,71)…(–0,26) kg.Conclusion. DRA does not have significant advantages over tetrapolar multifrequency BIM when assessing the body composition in hemodialysis patients. Цель исследования: сравнить эффективность использования двухэнергетической рентгеновской абсорбциометрии (ДРА) и биоимпедансометрии (БИМ) в оценке компонентного состава тела гемодиализных пациентов.Материалы и методы: обследовано 67 пациентов, получающих лечение программным гемодиализом (ГД), среди них 23 мужчины и 44 женщины, средний возраст 54±14,4 года. Для оценки компонентного состава тела использовали БИМ и ДРА.Результаты. Результаты определения общей мышечной массы тела, полученной по результатам ДРА и БИМ сравнили с использованием метода Блэнда–Альтмана. Коэффициент корреляции между показателями составил r=0,994, p<0,0001, дельта (M±s) составила –0,48±0,91 кг, ДИ 95% (–0,71)… (–0,26) кг.Заключение: ДРА не имеет значимых преимуществ по сравнению с тетраполярной мультичастотной БИМ при оценке компонентного состава тела у больных на гемодиализе.

Impact of phenolic-rich olive leaf extract on blood pressure, plasma lipids and inflammatory markers: a randomised controlled trial

Purpose Dietary polyphenols have been demonstrated to favourably modify a number of cardiovascular risk markers such as blood pressure (BP), endothelial function and plasma lipids. We conducted a randomised, double-blind, controlled, crossover trial to investigate the effects of a phenolic-rich olive leaf extract (OLE) on BP and a number of associated vascular and metabolic measures. Methods A total of 60 pre-hypertensive [systolic blood pressure (SBP): 121–140 mmHg; diastolic blood pressure (DBP): 81–90 mmHg] males [mean age 45 (±SD 12.7 years, BMI 26.7 (±3.21) kg/m2] consumed either OLE (136 mg oleuropein; 6 mg hydroxytyrosol) or a polyphenol-free control daily for 6 weeks before switching to the alternate arm after a 4-week washout. Results Daytime [−3.95 (±SD 11.48) mmHg, p = 0.027] and 24-h SBP [−3.33 (±SD 10.81) mmHg, p = 0.045] and daytime and 24-h DBP [−3.00 (±SD 8.54) mmHg, p = 0.025; −2.42 (±SD 7.61) mmHg, p = 0.039] were all significantly lower following OLE intake, relative to the control. Reductions in plasma total cholesterol [−0.32 (±SD 0.70) mmol/L, p = 0.002], LDL cholesterol [−0.19 (±SD 0.56) mmol/L, p = 0.017] and triglycerides [−0.18 (±SD 0.48), p = 0.008] were also induced by OLE compared to control, whilst a reduction in interleukin-8 [−0.63 (±SD 1.13) pg/ml; p = 0.026] was also detected. Other markers of inflammation, vascular function and glucose metabolism were not affected. Conclusion Our data support previous research, suggesting that OLE intake engenders hypotensive and lipid-lowering effects in vivo

Effect of the COVID-19 pandemic on surgery for indeterminate thyroid nodules (THYCOVID): a retrospective, international, multicentre, cross-sectional study

Background Since its outbreak in early 2020, the COVID-19 pandemic has diverted resources from non-urgent and elective procedures, leading to diagnosis and treatment delays, with an increased number of neoplasms at advanced stages worldwide. The aims of this study were to quantify the reduction in surgical activity for indeterminate thyroid nodules during the COVID-19 pandemic; and to evaluate whether delays in surgery led to an increased occurrence of aggressive tumours.Methods In this retrospective, international, cross-sectional study, centres were invited to participate in June 22, 2022; each centre joining the study was asked to provide data from medical records on all surgical thyroidectomies consecutively performed from Jan 1, 2019, to Dec 31, 2021. Patients with indeterminate thyroid nodules were divided into three groups according to when they underwent surgery: from Jan 1, 2019, to Feb 29, 2020 (global prepandemic phase), from March 1, 2020, to May 31, 2021 (pandemic escalation phase), and from June 1 to Dec 31, 2021 (pandemic decrease phase). The main outcomes were, for each phase, the number of surgeries for indeterminate thyroid nodules, and in patients with a postoperative diagnosis of thyroid cancers, the occurrence of tumours larger than 10 mm, extrathyroidal extension, lymph node metastases, vascular invasion, distant metastases, and tumours at high risk of structural disease recurrence. Univariate analysis was used to compare the probability of aggressive thyroid features between the first and third study phases. The study was registered on ClinicalTrials.gov, NCT05178186.Findings Data from 157 centres (n=49 countries) on 87 467 patients who underwent surgery for benign and malignant thyroid disease were collected, of whom 22 974 patients (18 052 [78 center dot 6%] female patients and 4922 [21 center dot 4%] male patients) received surgery for indeterminate thyroid nodules. We observed a significant reduction in surgery for indeterminate thyroid nodules during the pandemic escalation phase (median monthly surgeries per centre, 1 center dot 4 [IQR 0 center dot 6-3 center dot 4]) compared with the prepandemic phase (2 center dot 0 [0 center dot 9-3 center dot 7]; p<0 center dot 0001) and pandemic decrease phase (2 center dot 3 [1 center dot 0-5 center dot 0]; p<0 center dot 0001). Compared with the prepandemic phase, in the pandemic decrease phase we observed an increased occurrence of thyroid tumours larger than 10 mm (2554 [69 center dot 0%] of 3704 vs 1515 [71 center dot 5%] of 2119; OR 1 center dot 1 [95% CI 1 center dot 0-1 center dot 3]; p=0 center dot 042), lymph node metastases (343 [9 center dot 3%] vs 264 [12 center dot 5%]; OR 1 center dot 4 [1 center dot 2-1 center dot 7]; p=0 center dot 0001), and tumours at high risk of structural disease recurrence (203 [5 center dot 7%] of 3584 vs 155 [7 center dot 7%] of 2006; OR 1 center dot 4 [1 center dot 1-1 center dot 7]; p=0 center dot 0039).Interpretation Our study suggests that the reduction in surgical activity for indeterminate thyroid nodules during the COVID-19 pandemic period could have led to an increased occurrence of aggressive thyroid tumours. However, other compelling hypotheses, including increased selection of patients with aggressive malignancies during this period, should be considered. We suggest that surgery for indeterminate thyroid nodules should no longer be postponed even in future instances of pandemic escalation.Funding None.Copyright (c) 2023 Published by Elsevier Ltd. All rights reserved