3,180 research outputs found
Flight Tests, Performances and Flight Certification of a Twin-Engine Light Aircraft
This paper deals with flight test activities performed on P2006T, a twin-engine light aircraft recently designed and produced by Tecnam. Research activities and flight tests have been conducted during the flight certification of P2006T for the normal category under CS-23. All the acquired data and flight results presented have been focused on both aircraft certification and on aircraft performances, stability and flight qualities measurement. The data have been acquired through a light, accurate and reliable flight instrumentation available at DIAS (Department of Aerospace Engineering). Some flight data about aircraft leveled speed, stall speed, climb characteristics and ground performances (take-off and landing) will be presented. After preliminary flight tests, winglets have been designed and added to the final configuration in order to obtain good climb performances also in OEI (One Engine Inoperative) conditions. Accurate stall tests have been performed in all configurations and influence of both entry-rate and load factor on stall speed have been highlighted. Excellent ground performances have been measured with short take-off and landing distances compared with similar airplanes. All measured flight performances can be considered very good for this aircraft category and have been used to demonstrate aircraft safety and to obtain CS23 certification
Photometric stability analysis of the Exoplanet Characterisation Observatory
Photometric stability is a key requirement for time-resolved spectroscopic
observations of transiting extrasolar planets. In the context of the Exoplanet
Characterisation Observatory (EChO) mission design, we here present and
investigate means of translating spacecraft pointing instabilities as well as
temperature fluctuation of its optical chain into an overall error budget of
the exoplanetary spectrum to be retrieved. Given the instrument specifications
as of date, we investigate the magnitudes of these photometric instabilities in
the context of simulated observations of the exoplanet HD189733b secondary
eclipse.Comment: submitted to MNRA
Checking diagnosability on centralized model of the system
International audienceIn this work, the problem of checking diagnosability on Discrete Event System (DES) is considered especially in centralized architecture. Many approaches in literature deals with diagnosability using one or more intermediate models. In this paper, we present a new model based diagnosability algorithms in the framework of set theory for deciding diagnosability, without any intermediate constructions or models and considering several faults at the same time
Suppression of nuclear factor-κB activity in macrophages by chylomicron remnants: modulation by the fatty acid composition of the particles
Current evidence indicates that chylomicron remnants (CMR) induce macrophage foam cell formation, an early event in atherosclerosis. Inflammation also plays a part in atherogenesis and the transcription factor nuclear factor-κB (NF-κB) has been implicated. In this study, the influence of CMR on the activity of NF-κB in macrophages and its modulation by the fatty acid composition of the particles were investigated using macrophages derived from the human monocyte cell line THP-1 and CMR-like particles (CRLPs). Incubation of THP-1 macrophages with CRLPs caused decreased NF-κB activation and downregulated the expression of phospho-p65–NF-κB and phospho-IκBα (pIκBα). Secretion of the inflammatory cytokines tumour necrosis factor α, interleukin-6 and monocyte chemoattractant protein-1, which are under NF-κB transcriptional control, was inhibited and mRNA expression for cyclooxygenase-2, an NF-κB target gene, was reduced. CRLPs enriched in polyunsaturated fatty acids compared with saturated or monounsaturated fatty acids had a markedly greater inhibitory effect on NF-κB binding to DNA and the expression of phospho-p65–NF-κB and pIκB. Lipid loading of macrophages with CRLPs enriched in polyunsaturated fatty acids compared with monounsaturated fatty acids or saturated fatty acids also increased the subsequent rate of cholesterol efflux, an effect which may be linked to the inhibition of NF-κB activity. These findings demonstrate that CMR suppress NF-κB activity in macrophages, and that this effect is modulated by their fatty acid composition. This downregulation of inflammatory processes in macrophages may represent a protective effect of CMR which is enhanced by dietary polyunsaturated fatty acids
Combining the Hybrid Functional Method with Dynamical Mean-Field Theory
We present a new method to compute the electronic structure of correlated
materials combining the hybrid functional method with the dynamical mean-field
theory. As a test example of the method we study cerium sesquioxide, a strongly
correlated Mott-band insulator. The hybrid functional part improves the
magnitude of the pd-band gap which is underestimated in the standard
approximations to density functional theory while the dynamical mean-field
theory part splits the 4f-electron spectra into a lower and an upper Hubbard
band.Comment: 5 pages, 2 figures, replaced with revised version, published in
Europhys. Let
Light and Low Relative Humidity Increase Antioxidants Content in Mung Bean (Vigna radiata L.) Sprouts.
Modulating Vapor Pressure Deficit in the Plant Micro-Environment May Enhance the Bioactive Value of Lettuce
Plasmacytoid dendritic cells migrate in afferent skin lymph (Correction: vol 180, pg 5963, 2008)
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