SYMPTOMS OF INFANTS TOOTH GERMINATION: CONDITION OR DISEASE?

Aim. The purpose of this study was for identify the main orerall symptoms. Typilal for teething of children first year of life, including prematures, because uncontrolled using of medicines car lead of to advers and negative reactions.Materials and methods. The results of random survey of it children from 1 month to 1 year. 42 boys (55,3 %) and girls (44,7%) full-term Group included 40 children (63%), 36 children (47%) were included in preterm infants group.Results. The appearance of the first teeth is move common in 6-8 months оf babies life, painful teething was noted in 30 children (39,5 %). The most often symptoms were irritability, drooling, desire to bite. For relief of symptoms of 64 children, there was using medical funds. Of them prevailed gels (92,1% ).Conclusion. There is no specific symptoms of teething. To relive symptoms it is advisable to use safe medicines, pretembly of plant origin

The first Non-LRV RNA virus in leishmania

In this work, we describe the first Leishmania-infecting leishbunyavirus—the first virus other than Leishmania RNA virus (LRV) found in trypanosomatid parasites. Its host is Leishmania martiniquensis, a human pathogen causing infections with a wide range of manifestations from asymptomatic to severe visceral disease. This virus (LmarLBV1) possesses many characteristic features of leishbunyaviruses, such as tripartite organization of its RNA genome, with ORFs encoding RNA-dependent RNA polymerase, surface glycoprotein, and nucleoprotein on L, M, and S segments, respectively. Our phylogenetic analyses suggest that LmarLBV1 originated from leishbunyaviruses of monoxenous trypanosomatids and, probably, is a result of genomic re-assortment. The LmarLBV1 facilitates parasites’ infectivity in vitro in primary murine macrophages model. The discovery of a virus in L. martiniquensis poses the question of whether it influences pathogenicity of this parasite in vivo, similarly to the LRV in other Leishmania species