Calculation of the number of displacements in cascades of identical particle collisions

Calculation of total number of ionizations, excitations, and other displacements in cascades of identical particle collision

Immunobiological and morphofunctional indicators with dysbacteriosis of the intestine of rabbits

The article presents results of research of dynamics of morphological, biochemical, haematological and immunological parameters when changing the quantity and species of microorganisms of intestinal microbiocenosis of the rabbits. With the dominance of pathogenic bacteria in rabbit intestinal microbiocenoses, the titer of bifidumbacteria was 10-5-10-4, a decrease in the number of lactobacilli, an increase in the number of enterobacteria, a correlation between the colonization index and the degree of adhesion of bacteria was revealed; an increase in the total number of leukocytes, lymphocytes, erythrocytes, hematocrit, alanine aminotransferase level, aspartate aminotransferase, lactate dehydrogenase, total bilirubin, α-amylase, albumin, alkaline phosphatase, T-killer level, NK cells, concentration of C-reactive protein. We observed a decrease in the concentration of hemoglobin, monocytes, total protein level, T-lymphocytes, T-helpers, B-lymphocytes, phagocytic index, phagocytic activity of leukocytes, NST-spontaneous, NST-stimulated. Dynamics of morphological indicators was characterized by a disorder of the circulation of organs, a predominance of dystrophic and necrotic processes in the tissues and organs of the cardiovascular, respiratory, digestive, excretory system. Infiltration with mononuclear and segmented leukocytes was noted, diffuse lymphoid proliferation of the mucous membranes of the organs, hyperemia, edema, multiple hemorrhages, accumulation of hemorrhagic exudate in the lumen of the respiratory, digestive and urogenital tracts. Observed catarrhal-hemorrhagic inflammation of the gastrointestinal tract; mucous membrane of the stomach, small and large intestines edematic, hyperemic, with hemorrhages, covered with mucus, fibrinous films, with necrotic areas. The signs of acute diffuse interstitial nephritis, characterized by proliferation of connective tissue cells with a predominance of lipoblast and epithelioid cells, are revealed. In the presence of bacterial cells in the lumen of the tubules, the parenchyma of the cortical and medullar layers was marked by microabscesses. Accidental transformation of the thymus was observed, characterized by signs of a circulatory disorder, a decrease in the area of the cortex, the formation of cysts; signs of diffuse hyperplasia of the spleen with necrobiotic changes in the foci of proliferation, reduction of the area of lymphoid follicles, expansion of the area occupied by the red pulp of follicles, hyperplasia of follicles of white pulp with foci of necrosis. Identified multiple bacterial embolism of blood vessels, developed signs of hemorrhagic Diathesis, watched the development of sign infiltrative itch processes

ETIOLOGICAL STRUCTURE AND DIFFERENTIAL DIAGNOSTICS OF SALMONELLOSIS OF BIRDS

The article presents the results of a study of the etiological structure and differential diag-nostic signs of avian salmonellosis. When identifying bacteria isolated from 128 blood samples of chickens with the use of rapid test "Salmonella latex kit" established the dominance of cultures of the microorganisms Salmonella spp. - of 10.94% (14 samples); 10 strains (71,43%) were attributed to Salmonella gallinarum, 4 (of 28.57%) to Salmonella pullorum. The overall level of resistance of Salmonella to ampicillin - 57,58%; tetracycline - 60,61%; streptomycin - 66,67%; had to 57,58%; 60,61% and 66,67% are sensitivity to norfloxacin amounted to 69,70%, to ceftazidime - 78,79%, enrofloxacin - 57,58%, ciprofloxacin - 69,70% of the tested strains. At postmortem examination the most frequently detected signs of pericarditis, hemorrhagic pneumonia, aeroscout, catarrhal-hemorrhagic enteritis, perihepatitis, hyperplasia of the spleen. The most frequently detected signs of pericarditis, aeroscout, catarrhal-hemorrhagic gastroenterocolitis, perihepatitis, inflam-mation of the ovaries, hyperplasia of the spleen. Revealed signs of congestive hyperemia, macrophage reaction, hyperplasia and plasmocytomas of lymphocyte transformation, increase the permeability of microcirculatory vessels, lymphoid-cellular infil-tration of loose fibrous connective tissue, perivascular oedema, disseminated thrombosis, proliferation of lymphocytes from lymph nodes, spleen, liver, and pancreas. In violation of the porosity of the blood vessels of serous membranes of organs were observed extensive serous oedema, the output of the formed elements of blood and the loss of fibrinogen

The evaluation of intensity of formation of biomembrane by microscopic fungi of the Candida genus

In the modern world, one of the most serious problems in the treatment of chronic infectious diseases of animals is the creation of biomembranes by microorganisms, in which they become inaccessible to the vast majority of antimicrobial agents. In this study, we investigated the structural and functional features of three strains of Candida albicans, Candida tropicalis and Candida africana on the ability to form biomembranes. A reliable diagnostic algorithm for quantitative evaluation of Candida biomembranes and remaining native cells has been tested. The dependence of the biomembrane formation process and the number of remaining native cells on the time of cultivation was determined. Morphological studies of the process of biomembrane formation without architectonics disturbance with the use of scanning electron microscope and cell holographic microscope were carried out. © 2018, Advanced Scientific Research. All rights reserved