On the structure of subsets of an orderable group with some small doubling properties

The aim of this paper is to present a complete description of the structure of subsets S of an orderable group G satisfying |S^2| = 3|S|-2 and is non-abelian

Decoherence in rf SQUID Qubits

We report measurements of coherence times of an rf SQUID qubit using pulsed microwaves and rapid flux pulses. The modified rf SQUID, described by an double-well potential, has independent, in situ, controls for the tilt and barrier height of the potential. The decay of coherent oscillations is dominated by the lifetime of the excited state and low frequency flux noise and is consistent with independent measurement of these quantities obtained by microwave spectroscopy, resonant tunneling between fluxoid wells and decay of the excited state. The oscillation's waveform is compared to analytical results obtained for finite decay rates and detuning and averaged over low frequency flux noise.Comment: 24 pages, 13 figures, submitted to the journal Quantum Information Processin

Immunohistochemical localization of NPY, VIP and 5-HT in the thyroid gland of the lizard, Podarcis sicula.

The thyroid gland of the lizard Podarcis sicula was immunohistochemically studied in adult male specimens using specific antibodies against NPY, VIP and 5-HT and the avidin-biotin peroxidase complex (ABC) procedure to localize the three peptides. Fine beaded VIP-immunoreactive nerve fibers ran between the follicles, and VIP-immunoreactivity was evenly distributed in the apical cytoplasm of follicular cells. NPY-immunoreactive fibers were found around the follicles, and, in the cells, immunoreactivity was localizated only in the cellular apices. Immunoreactivity to 5-HT was observed in the colloid, with a concentration in the follicular lumen exceeding that in the follicular cells. In fact, most follicles showed immunoreactivity in the cytoplasmic bridges formed between the apical portion of the follicular cells and the colloid

Time Domain Source Parameter Estimation of Natural and Man-Induced Microearthquakes at the Geysers Geothermal Field

Water injection in geothermal areas is the preferential strategy to sustain the natural production of geothermal resources. In this context, monitoring microearthquakes is a fundamental tool to track changes in the reservoirs in terms of soil composition, response to injections, and resource exploitation with space and time. Therefore, refined source characterization is crucial to better estimate the size, source mechanism, and rupture process of microearthquakes, as they are possibly related to industrial activities, and to identify any potential variation in the background seismicity. Standard approaches for source parameter estimation are ordinarily based on the modelling of Fourier displacement spectra and its characteristic parameters: the low-frequency spectral level and corner frequency. Here, we apply an innovative time domain technique that uses the curves of P-wave amplitude vs. time along the seismogram. This methodology allows estimation of seismic moment, source radius, and stress release from the plateau level and the corner time of the average logarithm of P-wave displacement versus time with the assumption of a triangular moment rate function, uniform rupture speed, and a constant/frequency-independent Q-factor. In the current paper, this time domain methodology is implemented on a selected catalog of microearthquakes consisting of 83 events with a moment magnitude ranging between 1.0 and 1.5 that occurred during a 7-year period (2007–2014) of fluid extraction/injection around Prati-9 and Prati-29 wells at The Geysers geothermal field. The results show that the time domain technique provides accurate seismic moment (moment magnitude) and rupture duration/radius estimates of microearthquakes down to the explored limit (M 1) while accounting for the anelastic attenuation effect in the radiated high-frequency wavefield. The retrieved source radius vs. moment scaling is consistent with a self-similar, constant stress drop scaling model, which proves an appropriate attenuation correction and the validity of the assumed, triangular moment rate function for microearthquake ruptures. Two alternative mechanical models are proposed to explain the observed difference (about two orders of magnitude) in the retrieved average stress release estimates between the time and frequency domain methods. We argue that the two quantities may not refer to the same physical quantity representing the stress release of earthquake ruptures. Either the smaller stress release values from the time domain method may indicate a larger fracture area (by a factor of 20) radiating the observed P-waveforms than the one estimated from the corner frequencies, or the frequency domain estimate is a proxy for dynamic stress release while the time domain is more representative of the static release. The latter is associated with a much lower dynamic friction value than static friction value at the fault during the rupture process

GH therapy in adult GH deficiency: a review of treatment schedules and the evidence for low starting doses.

Recombinant human growth hormone (GH) has been licensed for use in adult patients with GH deficiency (GHD) for over 15 years. Early weight- and surface area-based dosing regimens were effective but resulted in supraphysiological levels of insulin-like growth factor-I (IGF-I) and increased incidence of side effects. Current practice has moved towards individualized regimens, starting with low GH doses and gradually titrating the dose according to the level of serum IGF-I to achieve an optimal dose. Here we present the evidence supporting the dosing recommendations of current guidelines and consider factors affecting dose responsiveness and parameters of treatment response. The published data discussed here lend support for the use of low GH dosing regimens in adult GHD. The range of doses defined as 'low dose' in the studies discussed here (~1-4 mg/week) is in accordance with those recommended in current guidelines and encompasses the dose range recommended by product labels

Decoherence in rf SQUID Qubits

We report measurements of coherence times of an rf SQUID qubit using pulsed microwaves and rapid flux pulses. The modified rf SQUID, described by an double-well potential, has independent, in situ, controls for the tilt and barrier height of the potential. The decay of coherent oscillations is dominated by the lifetime of the excited state and low frequency flux noise and is consistent with independent measurement of these quantities obtained by microwave spectroscopy, resonant tunneling between fluxoid wells and decay of the excited state. The oscillation's waveform is compared to analytical results obtained for finite decay rates and detuning and averaged over low frequency flux noise.Comment: 24 pages, 13 figures, submitted to the journal Quantum Information Processin

Effects of dietary supplementation of conjugated linoleic acids and their inclusion in semen extenders on bovine sperm quality

Isomers of conjugated linoleic acid (CLA) enhances circulating insulin-like growth factor I (IGF-I) levels. Furthermore, fertility rate of breeding bulls is positively correlated to seminal plasma IGF-I concentration. Our objective was to evaluate the effect of dietary CLA supplementa-tion and inclusion to the semen extender on bovine semen quality and freezability. Fourteen bulls, randomly assigned to control (CTL) and CLA (50 g/day) groups, were supplemented for 10 weeks. Samples were collected at Weeks −2 (before supplementation), 0, 4, 6 (during supplementation), 10, and 11 (after supplementation). Blood and seminal plasma were analyzed for IGF-I; the ejaculates were frozen in the following subgroups: CTL (no addition to semen extender), CLA c9, t11 (50 µM), CLA c9, t11 (100 µM), CLA t10, c12 (50 µM), CLA t10, c12 (100 µM), and CLA mix (50 µM each of CLA c9, t11 and CLA t10, c12). Sperm motility, morphology, viability, mitochondrial membrane potential, and reactive oxidative species were assessed. CLA supplementation decreased ejaculates’ total volume, increased sperm concentration, beat cross frequency, and decreased oxidative stress; it also increased plasma and seminal plasma IGF-I levels compared to the CTL. The inclusion of CLA c9, t11 100 µ M and CLA mixture in the extender increased live spermatozoa percentage post-thawing compared to other groups. Our results show a beneficial effect of CLA supplementation on semen quality; however, further studies evaluating fertilization rates are necessary to corroborate the results