Anesthesia Management in an Edentulous Patient with Huge Parotid Tumour: Case Report

Huge head and neck tumors are known to cause difficult ventilation and difficult intubation. Edentulous mouth can result in difficult mask ventilation. Head and neck tumor resections can also present hemodynamic challenge, due to their proximity to large vessels. We herein report a clinical case of difficult ventilation due to large parotid tumor in an edentulous patient

Power-Aware QoS Enhancement in Multihop DS-CDMA Visual Sensor Networks

Abstract-We propose a quality-driven method for network resource allocation with transmission power control in a multihop Direct Sequence Code Division Multiple Access (DS-CDMA) Wireless Visual Sensor Network (WVSN). A multihop WVSN typically consists of source nodes that monitor different areas and relay nodes that retransmit recorded scenes. In order to achieve the best possible video quality at the receiver while consuming the least possible transmission power, we propose a joint optimization scheme that allocates the available resources among the nodes with respect to the imposed constraints. Moreover, we formulate a weighted bi-objective optimization problem and study the tradeoff between video quality and consumed transmission power. The simulation demonstrate that excessive transmission power is used when power control is omitted for a rather small quality gain for certain nodes

Reduced expression of the polymeric immunoglobulin receptor in pancreatic and periampullary adenocarcinoma signifies tumour progression and poor prognosis

The polymeric immunoglobulin receptor (pIgR) is a key component of the mucosal immune system that mediates epithelial transcytosis of immunoglobulins. High pIgR expression has been reported to correlate with a less aggressive tumour phenotype and an improved prognosis in several human cancer types. Here, we examined the expression and prognostic significance of pIgR in pancreatic and periampullary adenocarcinoma. The study cohort encompasses a consecutive series of 175 patients surgically treated with pancreaticoduodenectomy for pancreatic and periampullary adenocarcinoma in Malmö and Lund University Hospitals, Sweden, between 2001-2011. Tissue microarrays were constructed from primary tumours (n = 175) and paired lymph node metastases (n = 105). A multiplied score was calculated from the fraction and intensity of pIgR staining. Classification and regression tree analysis was used to select the prognostic cut-off. Unadjusted and adjusted hazard ratios (HR) for death and recurrence within 5 years were calculated. pIgR expression could be evaluated in 172/175 (98.3%) primary tumours and in 96/105 (91.4%) lymph node metastases. pIgR expression was significantly down-regulated in lymph node metastases as compared with primary tumours (p = 0.018). Low pIgR expression was significantly associated with poor differentiation grade (p < 0.001), perineural growth (p = 0.027), lymphatic invasion (p = 0.016), vascular invasion (p = 0.033) and infiltration of the peripancreatic fat (p = 0.039). In the entire cohort, low pIgR expression was significantly associated with an impaired 5-year survival (HR = 2.99, 95% confidence interval (CI) 1.71-5.25) and early recurrence (HR = 2.89, 95% CI 1.67-4.98). This association remained significant for survival after adjustment for conventional clinicopathological factors, tumour origin and adjuvant treatment (HR = 1.98, 95% CI 1.10-3.57). These results demonstrate, for the first time, that high tumour-specific pIgR expression signifies a more favourable tumour phenotype and that low expression independently predicts a shorter survival in patients with pancreatic and periampullary cancer. The mechanistic basis for the putative tumour suppressing properties of pIgR in these cancers merits further study

Principles and Working of Microturbine

A new small gas turbine technology is being developed which promises to bring the economic, environmental and convenience benefits, advancements in the automotive sector, generation of electricity and mechanical power needs of the commercial sector. The technology is of the microturbines.The micro turbine is an example of Micro Electro Mechanical Systems, which is efficiently used to develop power at a small scale. Microturbines are small combustion turbines approximately the size of a refrigerator with outputs of 25 kW to 500 kW. Microturbines are part of the future of onsite, or distributed energy and power generation

Abscess formation mimicking disease progression, in a patient with metastatic renal cell carcinoma during sunitinib treatment

Background: Renal cell carcinoma (RCC) represents approximately 3% of all adult cancers and is more common in males. Systemic treatment for RCC has improved following the introduction of tyrosine kinase inhibitors, such as sunitinib. The molecular targets of sunitinib are receptor tyrosine kinases (RTKs). Moreover, sunitinib has an additional anti-angiogenic effect through its inhibition of the vascular endothelial growth factor receptor activation.Case presentation: We present a case of intra-abdominal abscess formation mimicking disease progression, in a patient with metastatic renal cell carcinoma during sunitinib treatment.Conclusion: In the advancing era of molecular therapy of solid tumours, sunitinib has demonstrated significant efficacy in the post-cytokine setting treatment of metastatic renal cancer. Concurrently, however, increasing evidence has emerged to indicate that this class of drugs exert profound immunomodulatory effects on T cells and play major roles in immune tumor surveillance. © 2010 Michalaki et al; licensee BioMed Central Ltd

Unusual presentation of Mönckeberg&apos;s sclerosis in the thyroid vessels of three female patients

Histopathological findings of Mönckeberg&apos;s sclerosis in the thyroid vessels of three female patients are described. Two of the patients presented with papillary carcinoma and the third presented with two cystic adenomatous nodules. Lesions of chronic lymphocytic thyroiditis were observed in two of the cases. The presence of Mönckeberg&apos;s sclerosis is an indication for further examination of patients vascular systems because of the high risk for cardiovascular events. © 2009 Pulsus Group Inc. All rights reserved

Intranodal palisaded myofibroblastoma: A case report

Intranodal palisaded myofibroblastoma is a rare benign soft tissue tumor, almost always arising from inguinal lymph nodes. It usually presents as a painless, slow-growing inguinal mass. We report herein a case of an intranodal palisaded myofibroblastoma occurring in a 36-year-old man. The salient clinicopathologic features of this unusual tumor are presented and the literature is briefly reviewed. © 2010 Karvouni et al; licensee BioMed Central Ltd