Molecular gas and star formation in M81

We present IRAM 30m observations of the central 1.6 kpc of the spiral M81 galaxy. The molecular gas appears weak and with an unusual excitation physics. We discuss a possible link between low CO emission and weak FUV surface brightness.Comment: 2 pages, 2 figures, to appear in "Pathways through an eclectic Universe", J. H. Knapen, T. J. Mahoney, and A. Vazdekis (Eds.), ASP Conf. Ser., 200

Study of ISM tracers in galaxies

We collected data for two samples of normal and interacting galaxies for a total of 2953 galaxies having fluxes in one or more of the following wavebands: FIR, 21 cm line, CO(1-0) lines and soft X-ray. The large set of data obtained allowed us to revisit some of the already known relations between the different tracers of the interstellar medium (ISM), such as the link between the FIR flux and the CO line emission, the relation between X-ray emission and the blue or FIR luminosity. The relation lacking from observations for early-type galaxies has been discussed and explained in detail in the frame of a suitable theoretical model, obtained by coupling chemo-dynamical N-body simulations with a dusty spectrophotometric code of population synthesis.Comment: 2 pages, o appear in the Proceedings of the Conf. "From Stars to Galaxies: Building the Pieces to Build Up the Universe", Vallenari et al. eds., ASP Conf. Serie

Are truncated stellar disks linked to the molecular gas density?

We know that the slope of the radial, stellar light distribution in galaxies is well described by an exponential decline and this distribution is often truncated at a break radius ($R_{br}$). We don't have a clear understanding for the origin of these outer truncations and several hypotheses have been proposed to explain them. We want to test the various theories with direct observations of the cold molecular gas for a few truncated galaxies in comparison with the non-truncated ones. The answer to the existence of a possible link between truncated stellar disks and the molecular gas density cannot be obtained from CO maps in the literature, because so far there are no galaxies with a clear truncation observed in CO at high resolution.Comment: 3 pages, 6 figures, to appear in Astrophysics and Space Science (Apss), special issue of "Science with ALMA: a new era for Astrophysics" conference, ed. Dr. Bachille

Acquired von Willebrand syndrome in patients with monoclonal gammopathy of undetermined significance investigated using a mechanistic approach

BACKGROUND: Acquired von Willebrand syndrome (AVWS) has been reported to occur in association with monoclonal gammopathy, usually of undetermined significance (MGUS). It may present as a type 1 or type 2 von Willebrand factor (VWF) defect depending on the patient’s representation of large VWF multimers. MATERIALS AND METHODS: The mathematical model by Galvanin et al., already employed for studying inherited von Willebrand disease (VWD), was used to explore the pathogenic mechanisms behind MGUS-associated AVWS. RESULTS: The patients studied showed significantly reduced VWF levels and function; an increased VWF propeptide to VWF antigen ratio; and all VWF multimers present but in reduced quantities, with the low-molecular-weight VWF forms being significantly more represented than those of higher molecular weight. Our mathematical model revealed a significantly increased VWF elimination rate constant, with values similar to those of type Vicenza VWD. An even more increased VWF proteolysis rate constant was observed, with values one order of magnitude higher than in type 2A VWD but, in contrast, no loss of large multimers. The model predicted the same elimination rate for high- and low-molecular-weight VWF multimers, but proteolysis of the high-molecular-weight forms also contributes to the pool of low-molecular-weight oligomers, which explains why they were relatively over-represented. DISCUSSION: In MGUS-associated AVWS the increase of both clearance and proteolysis contributes to the circulating levels and multimer pattern of VWF, with a phenotype that appears to be a combination of type Vicenza and type 2A VWD. Hence, the mechanisms behind the onset of AVWS seem to differ from those of inherited VWD

New photometric investigation of the double ringed galaxy ESO474-G26. Unveiling the formation scenario

We present a detailed photometric study of the peculiar double ringed galaxy ESO474-G26. Near-Infrared (NIR) and optical data have been used, with the main goal to constrain the formation history of ESO474-G26. NIR photometry is fundamental in this kind of study, because gives better constraints on the Spectral Energy Distribution (SED) and well traces the older stellar population of the galaxy. This galaxy presents a very complex structure, with two almost orthogonal rings, one in the equatorial and another in the polar plane, around an elliptical-like object. Due to the peculiar morphology of ESO474-G26, we used both NIR images (J and K bands) to derive accurate analysis of the stellar light distribution, and optical images (in the B, V and R bands) to derive color profiles and color maps to study the structure of the rings. The observational characteristic of ESO474-G26 are typical of galaxies which have experienced some kind of interactions during their evolution. We investigated two alternatives: a merging process and an accretion event.Comment: 19 pages, 20 figures. Accepted for publication in Monthly Notices of the Royal Astronomical Society (MNRAS

2D Spectroscopy of Candidate Polar-Ring Galaxies: I. The Pair of Galaxies UGC 5600/09

Observations of the pair of galaxies VV 330 with the SCORPIO multimode instrument on the 6-m Special Astrophysical Observatory telescope are presented. Large-scale velocity fields of the ionized gas in H-alfa and brightness distributions in continuum and H-alfa have been constructed for both galaxies with the help of a scanning Fabry Perot interferometer. Long-slit spectroscopy is used to study the stellar kinematics. Analysis of the data obtained has revealed a complex structure in each of the pair components. Three kinematic subsystems have been identified in UGC 5600: a stellar disk, an inner gas ring turned with respect to the disk through ~80degrees, and an outer gas disk. The stellar and outer gas disks are noncoplanar. Possible scenarios for the formation of the observed multicomponent kinematic galactic structure are considered, including the case where the large-scale velocity field of the gas is represented by the kinematic model of a disk with a warp. The velocity field in the second galaxy of the pair, UGC 5609, is more regular. A joint analysis of the data on the photometric structure and the velocity field has shown that this is probably a late-type spiral galaxy whose shape is distorted by the gravitational interaction, possibly, with UGC 5600.Comment: 18 pages, 6 figure

Galaxy transmutations: The double ringed galaxy ESO 474-G26

Surface photometry and a 21cm HI line spectrum of the giant double-ringed galaxy ESO 474-G26 are presented. The morphology of this system is unique among the 30,000 galaxies with >B15. Two almost orthogonal optical rings with diameters of 60 and 40 kpc surround the central body (assuming H0=70 km/s/Mpc). The outer one is an equatorial ring, while the inner ring lies in a nearly polar plane. The rings have blue optical colors typical of late-type spirals. Both appear to be rotating around the central galaxy, so that this system can be considered as a kinematically confirmed polar ring galaxy. Its observational characteristics are typical of galaxy merger remnants. Although the central object has a surface brightness distribution typical of elliptical galaxies, it has a higher surface brightness for its effective radius than ordinary ellipticals. Possible origins of this galaxy are discussed and numerical simulations are presented that illustrate the formation of the two rings in the merging process of two spiral galaxies, in which the observed appearance of ESO 474-G26 appears to be a transient stage.Comment: Accepted for publication in A&

The Cerebellar Dopaminergic System

In the central nervous system (CNS), dopamine (DA) is involved in motor and cognitive functions. Although the cerebellum is not been considered an elective dopaminergic region, studies attributed to it a critical role in dopamine deficit-related neurological and psychiatric disorders [e.g., Parkinson's disease (PD) and schizophrenia (SCZ)]. Data on the cerebellar dopaminergic neuronal system are still lacking. Nevertheless, biochemical studies detected in the mammalians cerebellum high dopamine levels, while chemical neuroanatomy studies revealed the presence of midbrain dopaminergic afferents to the cerebellum as well as wide distribution of the dopaminergic receptor subtypes (DRD1-DRD5). The present review summarizes the data on the cerebellar dopaminergic system including its involvement in associative and projective circuits. Furthermore, this study also briefly discusses the role of the cerebellar dopaminergic system in some neurologic and psychiatric disorders and suggests its potential involvement as a target in pharmacologic and non-pharmacologic treatments