24 research outputs found

    Satellite university campuses and economic development in peripheral regions

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    Satellite university campuses – whereby established universities decentralise part of their activities, often to areas previously lacking a university – contribute to the diversification of university systems. While satellite campuses, due to their small scale and limited resources, might perform some activities less efficiently than their larger parent universities, we argue that they are uniquely placed to serve the needs of their localities. Based on the case of a satellite campus in North-West Italy, we show that: (i) the campus’ main contribution lies in widening access to higher education to residents who would not attend university in the absence of local provision; (ii) the campus contributes to local development also through research and business and community engagement, and by stimulating local demand for knowledge-intensive services; (iii) research and engagement are more effective for local development where local firms possess relevant absorptive capacity and where there is a favourable institutional framework

    DMTs and Covid-19 severity in MS: a pooled analysis from Italy and France

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    We evaluated the effect of DMTs on Covid-19 severity in patients with MS, with a pooled-analysis of two large cohorts from Italy and France. The association of baseline characteristics and DMTs with Covid-19 severity was assessed by multivariate ordinal-logistic models and pooled by a fixed-effect meta-analysis. 1066 patients with MS from Italy and 721 from France were included. In the multivariate model, anti-CD20 therapies were significantly associated (OR = 2.05, 95%CI = 1.39–3.02, p < 0.001) with Covid-19 severity, whereas interferon indicated a decreased risk (OR = 0.42, 95%CI = 0.18–0.99, p = 0.047). This pooled-analysis confirms an increased risk of severe Covid-19 in patients on anti-CD20 therapies and supports the protective role of interferon

    Achievable tolerances in robotic feature machining operations using a low-cost hexapod

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    Portable robotic machine tools potentially allow feature machining processes to be brought to large parts in various industries, creating an opportunity for capital expenditure and operating cost reduction. However, robots lack the machining capability of conventional equipment, which ultimately results in dimensional errors in parts. This work showcases a low-cost hexapod-based robotic machine tool and presents experimental research conducted to investigate how the widely researched robotic machining challenges, e.g. structural dynamics and kinematics, translate to achievable tolerance ranges in real-world production to highlight currently feasible applications and provide a context for considering technology improvements. Machining trials assess the total dimensional errors in the final part over multiple geometries. A key finding is error variation which is in the sub-millimetre range, although, in some cases, upper tolerance limits < 100 μm are achieved. Practical challenges are also noted. Most significantly, it is demonstrated that dimensional machining error is mainly systematic in nature and therefore that the total error can be dramatically reduced with in situ measurement and compensation. Potential is therefore found to achieve a flexible, high-performance robotic machining capability despite complex and diverse underlying scientific challenges. Overall, the work presented highlights achievable tolerances in low-cost robotic machining and opportunities for improvement, also providing a practical benchmark useful for process selection

    Operational modal identification in the presence of harmonic excitation

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    International audienceThe dynamic behavior of structures can be studied by the identification of their modal parameters. Classical modal analysis methods are based on the relation between the forces applied to structures (inputs) and their vibration responses (outputs). In real operational conditions it is difficult, or even impossible, to measure the excitation. For this reason, operational modal analysis approaches which consider only output data are proposed. However, most of these output-only techniques are proposed under the assumption of white noise excitation. If additional components, like harmonics for instance, are present in the exciting force, they will not be separated from the natural frequencies. Consequently, this assumption is no longer valid. In this context, an operational modal identification technique is proposed in order to only identify real poles and eliminate spurious ones. It is a method based on transmissibility functions. The objective of the proposed paper is to identify modal parameters in operational conditions in the presence of harmonic excitations. Identification is performed using a method based on transmissibility measurements and then with the classical stochastic subspace identification method, which is based on white noise excitation. These two methods are first applied to numerical examples and then to a laboratory test. Results validate the novel ability of the method based on transmissibility measurements to eliminate harmonics, contrary to the stochastic subspace identification approach
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