Increasing Geoheritage Awareness through Non-Formal Learning

Non-formal learning can have a crucial role in increasing citizens’ literacy to geoscience providing the opportunity to raise the public profile of geology and geomorphology. Starting from these remarks, the project presented here is one of the first attempts, at national level, aimed at achieving the territorial upgrading based on geoheritage enhancement. The project started thanks to a bottom-up input and involved the collaboration between scholars and local administrations and stakeholders for the valorization of a fluvial area within the Municipality of Castellarano (Emilia Apennines, Northern Italy). To achieve this aim of non-formal learning activities, based on the interpretation of the geoheritage, have been implemented. In fact, the investigated area includes valuable geological and geomorphological features which have been used, in the frame of the project here presented, to promote local geodiversity and geotourism. In particular, three geosites of regional significance were considered for the creation of EarthCaches, interpretative panels and guided excursions. Interpretative contents were designed to be educational, providing accurate but non-technical explanations. Attention was given in including illustrations playing an important role in the learning process. The results revealed that the implemented activities positively contribute to raising public awareness on the value of geoheritage

Promozione del sistema dei poli di innovazione nello spazio web: analisi dei contenuti e delle reti di relazioni virtuali

Nel progetto di analisi e modellizzazione del sistema regionale dei poli di innovazione in Toscana (www.poliinnovazione.unimore.it), abbiamo esaminato in modo sistematico le informazioni disponibili nei siti web dei poli con due obiettivi: (i) analizzare la varietà di linguaggio e di contenuti che caratterizzano i poli nella loro attività on line; (ii) verificare in che misura i poli facciano riferimento agli stessi enti, imprese, organizzazioni, progetti e, tra questi, alle organizzazioni/o attività direttamente collegate al polo (come ad esempio i soggetti gestori dei poli laboratori, gli incubatori, gli aderenti). Questo articolo presenta nella prima parte l'analisi linguistica dei siti web prodotti dai poli di innovazione ed ha lo scopo di fornire un insieme di variabili per la valutazione delle loro strategie di promozione. Il metro di valutazione principale è l'individuazione della fonte dei materiali pubblicati online dai singoli poli (materiali originali vs. materiali prodotti da terzi), che è stato usato come indicatore del livello di partecipazione di ogni singolo polo nelle strategie di promozione delle proprie attività. Si è quindi cercato di quantificare il livello di coinvolgimento che ogni polo ha espresso – nel proprio sito web – attraverso la pubblicazione di testi. L'analisi è stata condotta utilizzando la metodologia di linguistica dei corpora al fine di svolgere un'indagine sia quantitativa sia qualitativa (simile alla metodologia nota come CADS), ed è stata effettuata prendendo in esame 24 termini relativi ai concetti di innovazione e sviluppo, all'interno dei contenuti web pubblicati dai poli di innovazione (azienda, aziende, centri, collaborazione, conoscenze, finanziamenti, gestione, gestore, impresa, imprese, industriale, innovazione, poli, polo, processi, progetti, progetto, ricerca, servizi, servizio, sviluppo, tecnologia, tecnologie, territorio). Attraverso la valutazione dell'utilizzo dei 24 termini all'interno dei testi web, l'analisi ha evidenziato come le nozioni di innovazione e sviluppo vengano costruite dai singoli poli in termini sia di significato, sia di connotazione. Oltre all'analisi linguistica, l'analisi dei testi web ha consentito anche di individuare in maniera puntuale i domini principali e i link completi citati nei siti web dei poli. Adottando una prospettiva di analisi delle reti di relazioni, con queste informazioni sulle reti virtuali abbiamo analizzato due questioni rilevanti per la modellizzazione del sistema dei poli di innovazione: attraverso le citazioni dei domini principali mettiamo in evidenza in che misura i siti web i poli hanno comunicato le connessioni tra di loro e con i soggetti attivi nel trasferimento tecnologico; attraverso l'analisi dei link completi presenti nei siti web dei singoli poli possiamo individuare in che misura i poli fanno riferimento allo stesso spazio di informazioni. La presentazione è strutturata come segue: nella sezione 1 vengono presentati i dati, gli strumenti e la metodologia utilizzata nell'analisi linguistica; nella sezione 2 viene presentata l'analisi linguistica dei 24 termini selezionati ; nella sezione 3 sono analizzate le reti di relazioni virtuali, la sezione 4 conclude. L'appendice 1 presenta i dettagli tecnici sulla raccolta e successiva pulizia dei dati; l'appendice 2 contiene la lista dei principali link completi presenti all'interno dei siti dei poli presi in esame

Evaluating the performance of innovation intermediaries: insights from the experience of Tuscany’s innovation poles

With the growing importance of innovation intermediaries, particularly in the policy context, a need has emerged for appropriate instruments to evaluate their performance. The identification of appropriate performance indicators, however, has proved to be problematic. First, indicators are likely to influence the behavior of innovation intermediaries, not always in a desirable manner. Second, commonly used indicators focus on the immediate results achieved by the intermediaries, often disregarding the permanent behavioral changes that they can stimulate in their innovation system. Instead, we argue that the latter are particularly important for the evaluation of innovation intermediaries, whose success should be measured in terms of their ability to enable other organizations to improve their innovation capabilities. By focusing on an innovation policy intervention implemented by the Italian region of Tuscany in the period 2007-2013, we discuss the advantages and limitations of the indicators that have been set up by the regional government in order to evaluate the performance of innovation poles, a particular type of innovation intermediary, and discuss some feasible avenues for their improvement

Municipal Waste Selection and Disposal: Evidences from Lombardy

This article exploit a data base of 1.522 observations related to Lombardy’s municipalities to run a cross sectional estimation of the drivers of MW selection. We find no evidence of a significant correlation between the percentage of selected MW selection and market variables such as the unit charge for waste management, a result probably affected by the high degree of integration existing in Lombardy among collectors and disposal operators. On the contrary, we discover robust and significant correlation with a set of geographical, socio-economic, and political variables. Among the latter ones, we have a confirmations on the influence of party competition on the percentage of household recycling, with the left wing ruling parties more addressed to it than the rivals, and on the high correlation existing between MW selection and the implementation of a unit pricing scheme. Other positive correlations with the independent variable are shown by per-capita income, while quite surprisingly the education level of citizens seems to play no role

Variation and links among food and energy international prices. An analysis through VAR models from 2000 to 2012.

An adequate understanding of the dynamics that characterize the agri-food market is fundamental for the development of really efficient economic policies, especially after the two recent hikes in the prices of food commodities. The econometric literature provides today advanced analysis tools such as VAR models: these models are based on a system of equations in which each variable is regressed on a set of deterministic variables, on a number of l delays related to each covariate in the model. To test the effectiveness of this analytical tool at dealing with the issues related to agrifood economy we applied a VAR analysis on prices of major food and energy commodities (oil and biodiesel) referred to the period January 2005-December 2012. Our results identified statistically significant intertemporal relationships between the price of corn, soybeans, rapeseed and oil, and suggested the direction of these relationships; we could conclude that the price of corn and soybeans are generated in the energy market only. Moreover, we used as variables the share of commodities used for the production of biofuels, and we could observe that important alterations on the food market are due to the convenience in producing ethanol and biodiesel, since the portion of the crops used for energy is in direct competition with that devoted to the feeding. This kind of models, therefore, deal adequately with datas and issues of the agri-food system and provide an analytical basis to develop economic policies that take into account the complexity of the global food system

Case Report: Medullary thyroid carcinoma’s bone metastasis in a young patient affected by men -2A.

Case Report: Medullary thyroid carcinoma’s bone metastasis in a young patient affected by men -2A

AZIDOTHYMIDINE INDUCES APOPTOSIS AND INHIBITS CELL GROWTH AND TELOMERASE ACTIVITY OF HUMAN PARATHYROID CANCER IN CELL CULTURE

Telomerase activity has been correlated to parathyroid carcinoma. Because its role in acquisition of a malignant phenotype by parathyroid cells is unclear, we treated telomerase-positive cultured human parathyroid cancer cells with the telomerase inhibitor AZT, evaluating cell telomerase activity, cytotoxic effects, growth, and morphological changes. In vitro exposure of these cells to AZT correlated with inhibition of cell proliferation. Introduction: Parathyroid carcinoma represents an uncommon cause of primary hyperparathyroidism, whose spectrum of clinical presentation, degree of malignancy, and prognosis are difficult to be properly identified. Neck surgery, specifically an en bloc resection of primary tumor, is the only curative treatment. Alternatively, affected patients could undergo repetitive palliative surgical exeresis of metastatic nodules. It has been previously shown that telomerase activity is specifically present in parathyroid carcinoma cells, being absent in hyperplastic and adenomatous tissues. Thus, determination of telomerase activity could represent either a useful diagnostic molecular marker for human parathyroid carcinoma or a potential target for pharmacological intervention in a malignant neoplasia usually resistant to chemo- and radiotherapeutic interventions. Materials and Methods: To further investigate the role of telomerase activity in acquisition of a malignant phenotype by parathyroid cells, we treated telomeric repeat amplification protocol-positive cultured human parathyroid cells with the telomerase inhibitor zidovudine, 3_-azido-3_deoxythymidine (AZT), evaluating cell telomerase activity, growth characteristics, potential cytotoxic effects, and morphological changes. Results: Our findings indicate that in vitro exposure of human parathyroid cancer cells to AZT resulted in intracellular accumulation of AZT-monophosphate (AZT-MP) and inhibition of telomerase, which correlate with inhibition of human parathyroid cancer cell proliferation. Moreover, we also found that AZT induced an apoptotic rather than a necrotic type of cellular death. None of these effects were observed in human adenomatous parathyroid cells in culture. Conclusions: Altogether these results indicate that AZT may be a highly effective agent against cancer parathyroid cells proliferation, which is an extremely important observation for a neoplasia which shows lack of response to classical pharmacological and physical antiblastic treatments