168 research outputs found
ETEKOS experimental ecological system
The problem of changes in the ecology resulting, for example, in increases in water temperature because of discharges from large thermal power plants is considered. An experiment creating a model of such an ecological system is described
Towards the electron EDM search: Theoretical study of HfF+
We report first ab initio relativistic correlation calculations of potential
curves for ten low-lying electronic states, effective electric field on the
electron and hyperfine constants for the ^3\Delta_1 state of cation of a heavy
transition metal fluoride, HfF^+, that is suggested to be used as the working
state in experiments to search for the electric dipole moment of the electron.
It is shown that HfF^+ has deeply bound ^1\Sigma^+ ground state, its
dissociation energy is D_e=6.4 eV. The ^3\Delta_1 state is obtained to be the
relatively long-lived first excited state lying about 0.2 eV higher. The
calculated effective electric field E_eff=W_d|\Omega| acting on an electron in
this state is 5.84*10^{24}Hz/(e*cm)Comment: 4 page
Configuration interaction calculation of hyperfine and P,T-odd constants on ^{207}PbO excited states for the electron EDM experiments
We report first configuration interaction calculations of hyperfine constants
A_\parallel and the effective electric field W_d acting on the electric dipole
moment of the electron, in two excited electronic states of ^{207}PbO. The
obtained hyperfine constants, A_\parallel = -3826 MHz for the a(1) state and
A_\parallel = 4887 MHz for the B(1) state, are in very good agreement with the
experimental data, -4113 MHz and 5000 \pm 200 MHz, respectively. We find W_d =
-(6.1 ^{+1.8}_{-0.6}) 10^{24} Hz/(e cm) for a(1), and W_d = (8.0 \pm 1.6)
10^{24} Hz/(e cm) for B(1). The obtained values are analyzed and compared to
recent relativistic coupled cluster results and a semiempirical estimate of W_d
for the a(1) state.Comment: 6 pages, REVTeX4 style, submitted to Pthys.Rev.
Drug Agranulocytosis
The paper covers the problem associated with the wide availability and uncontrolled use of over-the-counter medicines, particularly analgesics, antipyretics, and anticatarrhal agents, which lead to the occurrence of adverse drug reactions and poisonings and to considerable economic and human losses. The mechanisms of the pathogenesis of drug agranu-locytosis due to the intake of nonsteroidal analgesics and the diagnosis and treatment of this disease are described in detail. The case presented by the authors clearly demonstrates that the possible development of life-threatening complications due to the use of even submaximal permitted doses of widely spread and available anticatarrhal drugs. Key words: antipyretics, analgesics, nonsteroidal anti-inflammatory drugs, drug agranulocytosis, trepanobiopsy, myelo-gram, intensive care unit
Towards the electron EDM search. Theoretical study of PbF
We report ab initio relativistic correlation calculations of potential curves
and spectroscopic constants for four lowest-lying electronic states of the lead
monofluoride. We also calculated parameters of the spin-rotational Hamiltonian
for the ground and the first excited states including P,T-odd and P-odd terms.
In particular, we have obtained hyperfine constants of the Pb nucleus.
For the state MHz, MHz and for
the A MHz, MHz. Our values of
the ground state hyperfine constants are in good agreement with the previous
theoretical studies. We discuss and explain seeming disagreement in the sign of
the constant with the recent experimental data. The effective
electric field on the electron , which is important for the planned
experiment to search for the electric dipole moment of the electron, is found
to be 3.3 * 10^{10} V/cm
On Nonperturbative Calculations in Quantum Electrodynamics
A new approach to nonperturbative calculations in quantum electrodynamics is
proposed. The approach is based on a regular iteration scheme for solution of
Schwinger-Dyson equations for generating functional of Green functions. The
approach allows one to take into account the gauge invariance conditions (Ward
identities) and to perform the renormalization program. The iteration scheme
can be realized in two versions. The first one ("perturbative vacuum")
corresponds to chain summation in the diagram language. In this version in
four-dimensional theory the non-physical singularity (Landau pole) arises which
leads to the triviality of the renormalized theory. The second version
("nonperturbative vacuum") corresponds to ladder summation and permits one to
make non-perturbative calculations of physical quantities in spite of the
triviality problem. For chiral-symmetrical leading approximation two terms of
the expansion of the first-step vertex function over photon momentum are
calculated. A formula for anomalous magnetic moment is obtained. A problem of
dynamical chiral symmetry breaking (DCSB) is considered, the calculations are
performed for renormalized theory in Minkowsky space. In the strong coupling
region DCSB-solutions arise. For the renormalized theory a DCSB-solution is
also possible in the weak coupling region but with a subsidiary condition on
the value of .Comment: 31 pages, Plain LaTex, no figures. Journal version: some discussion
and refs. are adde
An adaptive prefix-assignment technique for symmetry reduction
This paper presents a technique for symmetry reduction that adaptively
assigns a prefix of variables in a system of constraints so that the generated
prefix-assignments are pairwise nonisomorphic under the action of the symmetry
group of the system. The technique is based on McKay's canonical extension
framework [J.~Algorithms 26 (1998), no.~2, 306--324]. Among key features of the
technique are (i) adaptability---the prefix sequence can be user-prescribed and
truncated for compatibility with the group of symmetries; (ii)
parallelizability---prefix-assignments can be processed in parallel
independently of each other; (iii) versatility---the method is applicable
whenever the group of symmetries can be concisely represented as the
automorphism group of a vertex-colored graph; and (iv) implementability---the
method can be implemented relying on a canonical labeling map for
vertex-colored graphs as the only nontrivial subroutine. To demonstrate the
practical applicability of our technique, we have prepared an experimental
open-source implementation of the technique and carry out a set of experiments
that demonstrate ability to reduce symmetry on hard instances. Furthermore, we
demonstrate that the implementation effectively parallelizes to compute
clusters with multiple nodes via a message-passing interface.Comment: Updated manuscript submitted for revie
ΠΠΏΡΠΈΠΌΠΈΠ·Π°ΡΠΈΡ ΠΠΠΠ Ρ Π±ΠΎΠ»ΡΠ½ΡΡ Ρ ΠΎΡΡΡΡΠΌ ΡΠ΅ΡΠΏΠΈΡΠ°ΡΠΎΡΠ½ΡΠΌ Π΄ΠΈΡΡΡΠ΅ΡΡ-ΡΠΈΠ½Π΄ΡΠΎΠΌΠΎΠΌ, Π²ΡΠ·Π²Π°Π½Π½ΡΠΌ ΠΏΡΡΠΌΡΠΌΠΈ ΠΈ Π½Π΅ΠΏΡΡΠΌΡΠΌΠΈ ΠΏΠΎΠ²ΡΠ΅ΠΆΠ΄Π°ΡΡΠΈΠΌΠΈ ΡΠ°ΠΊΡΠΎΡΠ°ΠΌΠΈ
Objective: to study the clinical efficiency of undifferentiated and differentiated use of escalation and de-escalation procedures for optimizing positive end-expiratory pressure (PEEP) during mechanical ventilation in patients with acute respiratory distress syndrome (ARDS) resulting from direct and indirect damaging factors. Subjects and methods. During a prospective study, 24 examined patients (16 men, 8 women; their age was 22 to 65 years) with ARDS of different genesis were divided into 2 groups. Group A (n=11; 7 men, 4 women) and Group B (n=13; 9 men, 4 women) included patients with ARDS arising from both direct (gastric content aspiration, blunt chest injury with lung contusion, and acute bilateral bacterial pneumonia) and indirect (abdominal sepsis, severe nonthoracic injury, and acute massive blood loss) damaging factors. The results of treatment via differentiated or undifferentiated, according to the cause of ARDS, use of escalation and de-escalation procedures for PEEP optimization were assessed in Groups A and B patients. Results. The differentiated, according to the cause of ARDS, use of escalation and de-escalation procedures for PEEP optimization makes it possible to more effectively improve the parameters of pulmonary gas exchange and biomechanics and to reduce the length of respiratory support and stay in the intensive care unit, the incidence of ventilator-associated pneumonia, and mortality rates in patients with ARDS resulting from direct and indirect damaging factors. Conclusion. It is advisable to apply the differentiated, according to the cause of ARDS, approach to choosing escalation or de-escalation procedures to optimize PEEP in patients with ARDS of different genesis. Key words: acute respiratory distress syndrome, direct damaging factors, indirect damaging factors, mechanical ventilation, positive end-expiratory pressure, escalation PEEP optimization procedure, de-escalation PEEP optimization procedure, lung opening manoeuver.Π¦Π΅Π»Ρ ΠΈΡΡΠ»Π΅Π΄ΠΎΠ²Π°Π½ΠΈΡ β ΠΈΠ·ΡΡΠ΅Π½ΠΈΠ΅ ΠΊΠ»ΠΈΠ½ΠΈΡΠ΅ΡΠΊΠΎΠΉ ΡΡΡΠ΅ΠΊΡΠΈΠ²Π½ΠΎΡΡΠΈ Π½Π΅ Π΄ΠΈΡΡΠ΅ΡΠ΅Π½ΡΠΈΡΠΎΠ²Π°Π½Π½ΠΎΠ³ΠΎ ΠΈ Π΄ΠΈΡΡΠ΅ΡΠ΅Π½ΡΠΈΡΠΎΠ²Π°Π½Π½ΠΎΠ³ΠΎ ΠΏΡΠΈΠΌΠ΅Π½Π΅Π½ΠΈΡ ΡΡΠΊΠ°Π»Π°ΡΠΈΠΎΠ½Π½ΠΎΠ³ΠΎ ΠΈ Π΄Π΅ΡΡΠΊΠ°Π»Π°ΡΠΈΠΎΠ½Π½ΠΎΠ³ΠΎ ΡΠΏΠΎΡΠΎΠ±ΠΎΠ² ΠΎΠΏΡΠΈΠΌΠΈΠ·Π°ΡΠΈΠΈ ΠΏΠΎΠ»ΠΎΠΆΠΈΡΠ΅Π»ΡΠ½ΠΎΠ³ΠΎ Π΄Π°Π²Π»Π΅Π½ΠΈΡ Π² ΠΊΠΎΠ½ΡΠ΅ Π²ΡΠ΄ΠΎΡ
Π° Π² ΡΡΠ»ΠΎΠ²ΠΈΡΡ
ΠΈΡΠΊΡΡΡΡΠ²Π΅Π½Π½ΠΎΠΉ Π²Π΅Π½ΡΠΈΠ»ΡΡΠΈΠΈ Π»Π΅Π³ΠΊΠΈΡ
Ρ Π±ΠΎΠ»ΡΠ½ΡΡ
Ρ ΠΎΡΡΡΡΠΌ ΡΠ΅ΡΠΏΠΈΡΠ°ΡΠΎΡΠ½ΡΠΌ Π΄ΠΈΡΡΡΠ΅ΡΡ-ΡΠΈΠ½Π΄ΡΠΎΠΌΠΎΠΌ, ΡΠ°Π·Π²ΠΈΠ²ΡΠΈΠΌΡΡ Π²ΡΠ»Π΅Π΄ΡΡΠ²ΠΈΠ΅ Π²ΠΎΠ·Π΄Π΅ΠΉΡΡΠ²ΠΈΡ ΠΏΡΡΠΌΡΡ
ΠΈ Π½Π΅ΠΏΡΡΠΌΡΡ
ΠΏΠΎΠ²ΡΠ΅ΠΆΠ΄Π°ΡΡΠΈΡ
ΡΠ°ΠΊΡΠΎΡΠΎΠ². ΠΠ°ΡΠ΅ΡΠΈΠ°Π» ΠΈ ΠΌΠ΅ΡΠΎΠ΄Ρ. 24 ΠΎΠ±ΡΠ»Π΅Π΄ΠΎΠ²Π°Π½Π½ΡΡ
Π±ΠΎΠ»ΡΠ½ΡΡ
(16 ΠΌΡΠΆΡΠΈΠ½, 8 ΠΆΠ΅Π½ΡΠΈΠ½, Π²ΠΎΠ·ΡΠ°ΡΡ ΠΎΡ 22 Π΄ΠΎ 65 Π»Π΅Ρ) Ρ ΠΠ ΠΠ‘ ΡΠ°Π·Π»ΠΈΡΠ½ΠΎΠ³ΠΎ Π³Π΅Π½Π΅Π·Π° Π² Ρ
ΠΎΠ΄Π΅ ΠΏΡΠΎΡΠΏΠ΅ΠΊΡΠΈΠ²Π½ΠΎΠ³ΠΎ ΠΈΡΡΠ»Π΅Π΄ΠΎΠ²Π°Π½ΠΈΡ Π±ΡΠ»ΠΈ ΡΠ°Π·Π΄Π΅Π»Π΅Π½Ρ Π½Π° 2 Π³ΡΡΠΏΠΏΡ. ΠΡΡΠΏΠΏΠ° Π (Ρ=11, 7 ΠΌΡΠΆΡΠΈΠ½, 4 ΠΆΠ΅Π½ΡΠΈΠ½Ρ) ΠΈ Π³ΡΡΠΏΠΏΠ° B (n=13, 9 ΠΌΡΠΆΡΠΈΠ½, 4 ΠΆΠ΅Π½ΡΠΈΠ½Ρ) β Π±ΠΎΠ»ΡΠ½ΡΠ΅ Ρ ΠΠ ΠΠ‘, ΡΠ°Π·Π²ΠΈΠ²ΡΠΈΠΌΡΡ Π²ΡΠ»Π΅Π΄ΡΡΠ²ΠΈΠ΅ Π²ΠΎΠ·Π΄Π΅ΠΉΡΡΠ²ΠΈΡ ΠΊΠ°ΠΊ ΠΏΡΡΠΌΡΡ
ΠΏΠΎΠ²ΡΠ΅ΠΆΠ΄Π°ΡΡΠΈΡ
ΡΠ°ΠΊΡΠΎΡΠΎΠ² (Π°ΡΠΏΠΈΡΠ°ΡΠΈΡ ΠΆΠ΅Π»ΡΠ΄ΠΎΡΠ½ΡΠΌ ΡΠΎΠ΄Π΅ΡΠΆΠΈΠΌΡΠΌ, ΡΡΠΏΠ°Ρ ΡΡΠ°Π²ΠΌΠ° Π³ΡΡΠ΄ΠΈ Ρ ΡΡΠΈΠ±ΠΎΠΌ Π»Π΅Π³ΠΊΠΈΡ
, ΠΎΡΡΡΠ°Ρ Π΄Π²ΡΡΡΠΎΡΠΎΠ½Π½ΡΡ Π±Π°ΠΊΡΠ΅ΡΠΈΠ°Π»ΡΠ½Π°Ρ ΠΏΠ½Π΅Π²ΠΌΠΎΠ½ΠΈΡ), ΡΠ°ΠΊ ΠΈ Π½Π΅ΠΏΡΡΠΌΡΡ
ΠΏΠΎΠ²ΡΠ΅ΠΆΠ΄Π°ΡΡΠΈΡ
ΡΠ°ΠΊΡΠΎΡΠΎΠ² (Π°Π±Π΄ΠΎΠΌΠΈΠ½Π°Π»ΡΠ½ΡΠΉ ΡΠ΅ΠΏΡΠΈΡ, ΡΡΠΆΠ΅Π»Π°Ρ Π½Π΅ΡΠΎΡΠ°ΠΊΠ°Π»ΡΠ½Π°Ρ ΡΡΠ°Π²ΠΌΠ°, ΠΎΡΡΡΠ°Ρ ΠΌΠ°ΡΡΠΈΠ²Π½Π°Ρ ΠΊΡΠΎΠ²ΠΎΠΏΠΎΡΠ΅ΡΡ). Π£ Π±ΠΎΠ»ΡΠ½ΡΡ
Π³ΡΡΠΏΠΏ Π ΠΈ Π ΠΎΡΠ΅Π½ΠΈΠ²Π°Π»ΠΈ ΡΠ΅Π·ΡΠ»ΡΡΠ°ΡΡ Π»Π΅ΡΠ΅Π½ΠΈΡ ΠΏΡΠΈ Π΄ΠΈΡΡΠ΅ΡΠ΅Π½ΡΠΈΡΠΎΠ²Π°Π½Π½ΠΎΠΌ ΠΈ Π½Π΅Π΄ΠΈΡΡΠ΅ΡΠ΅Π½ΡΠΈΡΠΎΠ²Π°Π½Π½ΠΎΠΌ, Π² Π·Π°Π²ΠΈΡΠΈΠΌΠΎΡΡΠΈ ΠΎΡ ΠΏΡΠΈΡΠΈΠ½ ΡΠ°Π·Π²ΠΈΡΠΈΡ ΠΠ ΠΠ‘, ΠΏΡΠΈΠΌΠ΅Π½Π΅Π½ΠΈΠΈ ΡΡΠΊΠ°Π»Π°ΡΠΈΠΎΠ½Π½ΠΎΠ³ΠΎ ΠΈΠ»ΠΈ Π΄Π΅ΡΡΠΊΠ°Π»Π°ΡΠΈΠΎΠ½Π½ΠΎΠ³ΠΎ ΡΠΏΠΎΡΠΎΠ±ΠΎΠ² ΠΎΠΏΡΠΈΠΌΠΈΠ·Π°ΡΠΈΠΈ ΠΠΠΠ. Π Π΅Π·ΡΠ»ΡΡΠ°ΡΡ. ΠΠΈΡΡΠ΅ΡΠ΅Π½ΡΠΈΡΠΎΠ²Π°Π½Π½ΠΎΠ΅, Π² Π·Π°Π²ΠΈΡΠΈΠΌΠΎΡΡΠΈ ΠΎΡ ΠΏΡΠΈΡΠΈΠ½ ΡΠ°Π·Π²ΠΈΡΠΈΡ ΠΠ ΠΠ‘, ΠΏΡΠΈΠΌΠ΅Π½Π΅Π½ΠΈΠ΅ ΡΡΠΊΠ°Π»Π°ΡΠΈΠΎΠ½Π½ΠΎΠ³ΠΎ ΠΈ Π΄Π΅ΡΡΠΊΠ°Π»Π°ΡΠΈΠΎΠ½Π½ΠΎΠ³ΠΎ ΡΠΏΠΎΡΠΎΠ±ΠΎΠ² ΠΎΠΏΡΠΈΠΌΠΈΠ·Π°ΡΠΈΠΈ ΠΠΠΠ ΠΏΠΎΠ·Π²ΠΎΠ»ΡΠ΅Ρ Π±ΠΎΠ»Π΅Π΅ ΡΡΡΠ΅ΠΊΡΠΈΠ²Π½ΠΎ ΡΠ»ΡΡΡΠΈΡΡ ΠΏΠΎΠΊΠ°Π·Π°ΡΠ΅Π»ΠΈ Π³Π°Π·ΠΎΠΎΠ±ΠΌΠ΅Π½Π° ΠΈ Π±ΠΈΠΎΠΌΠ΅Ρ
Π°Π½ΠΈΠΊΠΈ Π»Π΅Π³ΠΊΠΈΡ
, ΡΠΎΠΊΡΠ°ΡΠΈΡΡ ΠΏΡΠΎΠ΄ΠΎΠ»ΠΆΠΈΡΠ΅Π»ΡΠ½ΠΎΡΡΡ ΡΠ΅ΡΠΏΠΈΡΠ°ΡΠΎΡΠ½ΠΎΠΉ ΠΏΠΎΠ΄Π΄Π΅ΡΠΆΠΊΠΈ, ΠΏΡΠ΅Π±ΡΠ²Π°Π½ΠΈΡ Π² ΡΠ΅Π°Π½ΠΈΠΌΠ°ΡΠΈΠΎΠ½Π½ΠΎΠΌ ΠΎΡΠ΄Π΅Π»Π΅Π½ΠΈΠΈ, ΡΠ°ΡΡΠΎΡΡ ΡΠ°Π·Π²ΠΈΡΠΈΡ ΡΠ΅ΡΠΏΠΈΡΠ°ΡΠΎΡ-Π°ΡΡΠΎΡΠΈΠΈΡΠΎΠ²Π°Π½Π½ΠΎΠΉ ΠΏΠ½Π΅Π²ΠΌΠΎΠ½ΠΈΠΈ ΠΈ Π»Π΅ΡΠ°Π»ΡΠ½ΠΎΡΡΡ Ρ Π±ΠΎΠ»ΡΠ½ΡΡ
Ρ ΠΠ ΠΠ‘, ΡΠ°Π·Π²ΠΈΠ²ΡΠΈΠΌΡΡ Π½Π° ΡΠΎΠ½Π΅ ΠΏΡΡΠΌΡΡ
ΠΈ Π½Π΅ΠΏΡΡΠΌΡΡ
ΠΏΠΎΠ²ΡΠ΅ΠΆΠ΄Π°ΡΡΠΈΡ
ΡΠ°ΠΊΡΠΎΡΠΎΠ². ΠΠ°ΠΊΠ»ΡΡΠ΅Π½ΠΈΠ΅. Π£ Π±ΠΎΠ»ΡΠ½ΡΡ
Ρ ΠΠ ΠΠ‘ ΡΠ°Π·Π»ΠΈΡΠ½ΠΎΠ³ΠΎ Π³Π΅Π½Π΅Π·Π° ΡΠ΅Π»Π΅ΡΠΎΠΎΠ±ΡΠ°Π·Π½ΠΎ ΠΈΡΠΏΠΎΠ»ΡΠ·ΠΎΠ²Π°ΡΡ Π΄ΠΈΡΡΠ΅ΡΠ΅Π½ΡΠΈΡΠΎΠ²Π°Π½Π½ΡΠΉ, Π² Π·Π°Π²ΠΈΡΠΈΠΌΠΎΡΡΠΈ ΠΎΡ ΠΏΡΠΈΡΠΈΠ½Ρ ΡΠ°Π·Π²ΠΈΡΠΈΡ ΠΠ ΠΠ‘, ΠΏΠΎΠ΄Ρ
ΠΎΠ΄ ΠΊ Π²ΡΠ±ΠΎΡΡ ΡΡΠΊΠ°Π»Π°ΡΠΈΠΎΠ½Π½ΠΎΠ³ΠΎ ΠΈΠ»ΠΈ Π΄Π΅ΡΡΠΊΠ°Π»Π°ΡΠΈΠΎΠ½Π½ΠΎΠ³ΠΎ ΡΠΏΠΎΡΠΎΠ±ΠΎΠ² ΠΎΠΏΡΠΈΠΌΠΈΠ·Π°ΡΠΈΠΈ ΠΠΠΠ. ΠΠ»ΡΡΠ΅Π²ΡΠ΅ ΡΠ»ΠΎΠ²Π°: ΠΎΡΡΡΡΠΉ ΡΠ΅ΡΠΏΠΈΡΠ°ΡΠΎΡΠ½ΡΠΉ Π΄ΠΈΡΡΡΠ΅ΡΡ-ΡΠΈΠ½Π΄ΡΠΎΠΌ, ΠΏΡΡΠΌΡΠ΅ ΠΏΠΎΠ²ΡΠ΅ΠΆΠ΄Π°ΡΡΠΈΠ΅ ΡΠ°ΠΊΡΠΎΡΡ, Π½Π΅ΠΏΡΡΠΌΡΠ΅ ΠΏΠΎΠ²ΡΠ΅ΠΆΠ΄Π°ΡΡΠΈΠ΅ ΡΠ°ΠΊΡΠΎΡΡ, ΠΈΡΠΊΡΡΡΡΠ²Π΅Π½Π½Π°Ρ Π²Π΅Π½ΡΠΈΠ»ΡΡΠΈΡ Π»Π΅Π³ΠΊΠΈΡ
, ΠΏΠΎΠ»ΠΎΠΆΠΈΡΠ΅Π»ΡΠ½ΠΎΠ΅ Π΄Π°Π²Π»Π΅Π½ΠΈΠ΅ Π² ΠΊΠΎΠ½ΡΠ΅ Π²ΡΠ΄ΠΎΡ
Π°, ΡΡΠΊΠ°Π»Π°ΡΠΈΠΎΠ½Π½ΡΠΉ ΡΠΏΠΎΡΠΎΠ± ΠΎΠΏΡΠΈΠΌΠΈΠ·Π°ΡΠΈΠΈ ΠΠΠΠ, Π΄Π΅ΡΡΠΊΠ°Π»Π°ΡΠΈΠΎΠ½Π½ΡΠΉ ΡΠΏΠΎΡΠΎΠ± ΠΎΠΏΡΠΈΠΌΠΈΠ·Π°ΡΠΈΠΈ ΠΠΠΠ, ΠΏΡΠΈΠ΅ΠΌ Β«ΠΎΡΠΊΡΡΡΠΈΡΒ» Π»Π΅Π³ΠΊΠΈΡ
ΠΠ½ΡΠΎΡΠΌΠ°ΡΠΈΠ²Π½ΠΎΡΡΡ ΠΈΠ½Π΄Π΅ΠΊΡΠ° ΠΎΠΊΡΠΈΠ³Π΅Π½Π°ΡΠΈΠΈ ΠΏΡΠΈ Π΄ΠΈΠ°Π³Π½ΠΎΡΡΠΈΠΊΠ΅ ΠΎΡΡΡΠΎΠ³ΠΎ ΡΠ΅ΡΠΏΠΈΡΠ°ΡΠΎΡΠ½ΠΎΠ³ΠΎ Π΄ΠΈΡΡΡΠ΅ΡΡ-ΡΠΈΠ½Π΄ΡΠΎΠΌΠ°
Objective: to study the informative value of the oxygenation index as a criterion for the diagnosis of acute respiratory distress syndrome (ARDS) of varying genesis. Subjects and methods. Seventy-two patients, including 27 women and 45 men, aged 19 to 65 years admitted to an intensive care unit for various diseases, in whom ARDS was diagnosed on the basis of the traditional criteria, were prospectively examined. The authors analyzed the causes of acute respiratory failure, the time course of changes in gas exchange and PaO2/FiO2, X-ray picture, and the time of respiratory support when respiratory and nonrespiratory treatments were performed. Results. After correction of the extrapulmonary causes of impaired gas exchange, optimization of respiratory support parameters, and use of aggressive artificial ventilation methods and nonrespiratory treatments, 45 (62.5%) of the 72 examinees diagnosed as having ARDS showed a considerable gas exchange improvement and a steady increase in the oxygenation index more than 300; thus, these patients stopped meeting the criteria of ARDS. Conclusion. The oxygenation index is a rather vulnerable sign of ARDS, the time course of changes in which depends on many pulmonary and extrapulmonary causes, which necessitates a comprehensive evaluation of the degree of lung injury, the causes and severity of respiratory failure and, evidently, the refinement and expansion of the criteria for establishing this diagnosis. Key words: acute lung injury, acute respiratory distress syndrome, acute respiratory failure, oxygenation index.Π¦Π΅Π»Ρ ΠΈΡΡΠ»Π΅Π΄ΠΎΠ²Π°Π½ΠΈΡ . ΠΠ·ΡΡΠ΅Π½ΠΈΠ΅ ΠΈΠ½ΡΠΎΡΠΌΠ°ΡΠΈΠ²Π½ΠΎΡΡΠΈ ΠΈΠ½Π΄Π΅ΠΊΡΠ° ΠΎΠΊΡΠΈΠ³Π΅Π½Π°ΡΠΈΠΈ, ΠΊΠ°ΠΊ ΠΊΡΠΈΡΠ΅ΡΠΈΡ Π΄ΠΈΠ°Π³Π½ΠΎΡΡΠΈΠΊΠΈ ΠΠ ΠΠ‘ ΡΠ°Π·Π»ΠΈΡΠ½ΠΎΠ³ΠΎ Π³Π΅Π½Π΅Π·Π°. ΠΠ°ΡΠ΅ΡΠΈΠ°Π» ΠΈ ΠΌΠ΅ΡΠΎΠ΄Ρ. ΠΡΠΎΡΠΏΠ΅ΠΊΡΠΈΠ²Π½ΠΎ ΠΎΠ±ΡΠ»Π΅Π΄ΠΎΠ²Π°Π»ΠΈ 72 Π±ΠΎΠ»ΡΠ½ΡΡ
: 27 ΠΆΠ΅Π½ΡΠΈΠ½ ΠΈ 45 ΠΌΡΠΆΡΠΈΠ½, Π² Π²ΠΎΠ·ΡΠ°ΡΡΠ΅ ΠΎΡ 19 Π΄ΠΎ 65 Π»Π΅Ρ, ΠΏΠΎΡΡΡΠΏΠΈΠ²ΡΠΈΡ
Π² ΠΠ ΠΠ’ Ρ ΡΠ°Π·Π»ΠΈΡΠ½ΡΠΌΠΈ Π·Π°Π±ΠΎΠ»Π΅Π²Π°Π½ΠΈΡΠΌΠΈ, ΠΊΠΎΡΠΎΡΡΠΌ Π½Π° ΠΎΡΠ½ΠΎΠ²Π°Π½ΠΈΠΈ ΡΡΠ°Π΄ΠΈΡΠΈΠΎΠ½Π½ΡΡ
ΠΊΡΠΈΡΠ΅ΡΠΈΠ΅Π² Π±ΡΠ» ΡΡΡΠ°Π½ΠΎΠ²Π»Π΅Π½ Π΄ΠΈΠ°Π³Π½ΠΎΠ· ΠΠ ΠΠ‘. ΠΠ½Π°Π»ΠΈΠ·ΠΈΡΠΎΠ²Π°Π»ΠΈ ΠΏΡΠΈΡΠΈΠ½Ρ ΡΠ°Π·Π²ΠΈΡΠΈΡ ΠΠΠ, Π΄ΠΈΠ½Π°ΠΌΠΈΠΊΡ ΠΏΠΎΠΊΠ°Π·Π°ΡΠ΅Π»Π΅ΠΉ Π³Π°Π·ΠΎΠΎΠ±ΠΌΠ΅Π½Π° ΠΈ PaO2/FiO2, ΡΠ΅Π½ΡΠ³Π΅Π½ΠΎΠ³ΡΠ°ΡΠΈΡΠ΅ΡΠΊΠΎΠΉ ΠΊΠ°ΡΡΠΈΠ½Ρ ΠΈ ΡΡΠΎΠΊΠΎΠ² ΡΠ΅ΡΠΏΠΈΡΠ°ΡΠΎΡΠ½ΠΎΠΉ ΠΏΠΎΠ΄Π΄Π΅ΡΠΆΠΊΠΈ (Π Π) Π½Π° ΡΠΎΠ½Π΅ ΠΏΡΠΈΠΌΠ΅Π½Π΅Π½ΠΈΡ ΡΠ΅ΡΠΏΠΈΡΠ°ΡΠΎΡΠ½ΡΡ
ΠΈ Π½Π΅ ΡΠ΅ΡΠΏΠΈΡΠ°ΡΠΎΡΠ½ΡΡ
ΠΌΠ΅ΡΠΎΠ΄ΠΎΠ² Π»Π΅ΡΠ΅Π½ΠΈΡ. Π Π΅Π·ΡΠ»ΡΡΠ°ΡΡ. Π‘ΡΠ΅Π΄ΠΈ 72 ΠΎΠ±ΡΠ»Π΅Π΄ΠΎΠ²Π°Π½Π½ΡΡ
Π±ΠΎΠ»ΡΠ½ΡΡ
Ρ Π΄ΠΈΠ°Π³Π½ΠΎΠ·ΠΎΠΌ ΠΠ ΠΠ‘ Ρ 45 (62,5%) ΠΏΠΎΡΠ»Π΅ ΠΊΠΎΡΡΠ΅ΠΊΡΠΈΠΈ Π²Π½Π΅Π»Π΅Π³ΠΎΡΠ½ΡΡ
ΠΏΡΠΈΡΠΈΠ½ Π½Π°ΡΡΡΠ΅Π½ΠΈΠΉ Π³Π°Π·ΠΎΠΎΠ±ΠΌΠ΅Π½Π°, ΠΎΠΏΡΠΈΠΌΠΈΠ·Π°ΡΠΈΠΈ ΠΏΠ°ΡΠ°ΠΌΠ΅ΡΡΠΎΠ² ΡΠ΅ΡΠΏΠΈΡΠ°ΡΠΎΡΠ½ΠΎΠΉ ΠΏΠΎΠ΄Π΄Π΅ΡΠΆΠΊΠΈ, ΠΏΡΠΈΠΌΠ΅Π½Π΅Π½ΠΈΡ Π°Π³ΡΠ΅ΡΡΠΈΠ²Π½ΡΡ
ΠΌΠ΅ΡΠΎΠ΄ΠΎΠ² ΠΠΠ ΠΈ Π½Π΅ΡΠ΅ΡΠΏΠΈΡΠ°ΡΠΎΡΠ½ΡΡ
ΠΌΠ΅ΡΠΎΠ΄ΠΎΠ² Π»Π΅ΡΠ΅Π½ΠΈΡ ΡΠ΄Π°Π»ΠΎΡΡ Π΄ΠΎΠ±ΠΈΡΡΡΡ ΡΡΡΠ΅ΡΡΠ²Π΅Π½Π½ΠΎΠ³ΠΎ ΡΠ»ΡΡΡΠ΅Π½ΠΈΡ ΠΏΠΎΠΊΠ°Π·Π°ΡΠ΅Π»Π΅ΠΉ Π³Π°Π·ΠΎΠΎΠ±ΠΌΠ΅Π½Π° ΠΈ ΡΡΠΎΠΉΠΊΠΎΠ³ΠΎ ΠΏΠΎΠ²ΡΡΠ΅Π½ΠΈΡ ΠΈΠ½Π΄Π΅ΠΊΡΠ° ΠΎΠΊΡΠΈΠ³Π΅Π½Π°ΡΠΈΠΈ Π±ΠΎΠ»Π΅Π΅ 300 β ΡΠ°ΠΊΠΈΠΌ ΠΎΠ±ΡΠ°Π·ΠΎΠΌ, ΡΡΠΈ Π±ΠΎΠ»ΡΠ½ΡΠ΅ ΠΏΠ΅ΡΠ΅ΡΡΠ°Π»ΠΈ ΡΠΎΠΎΡΠ²Π΅ΡΡΡΠ²ΠΎΠ²Π°ΡΡ ΠΊΡΠΈΡΠ΅ΡΠΈΡΠΌ ΠΠ ΠΠ‘. ΠΠ°ΠΊΠ»ΡΡΠ΅Π½ΠΈΠ΅. ΠΠ½Π΄Π΅ΠΊΡ ΠΎΠΊΡΠΈΠ³Π΅Π½Π°ΡΠΈΠΈ ΡΠ²Π»ΡΠ΅ΡΡΡ Π΄ΠΎΡΡΠ°ΡΠΎΡΠ½ΠΎ ΡΡΠ·Π²ΠΈΠΌΡΠΌ ΠΏΡΠΈΠ·Π½Π°ΠΊΠΎΠΌ ΠΠ ΠΠ‘, Π΄ΠΈΠ½Π°ΠΌΠΈΠΊΠ° ΠΈΠ·ΠΌΠ΅Π½Π΅Π½ΠΈΠΉ ΠΊΠΎΡΠΎΡΠΎΠ³ΠΎ Π·Π°Π²ΠΈΡΠΈΡ ΠΎΡ ΠΌΠ½ΠΎΠ³ΠΈΡ
Π»Π΅Π³ΠΎΡΠ½ΡΡ
ΠΈ Π²Π½Π΅Π»Π΅Π³ΠΎΡΠ½ΡΡ
ΠΏΡΠΈΡΠΈΠ½, ΡΡΠΎ Π΄ΠΈΠΊΡΡΠ΅Ρ Π½Π΅ΠΎΠ±Ρ
ΠΎΠ΄ΠΈΠΌΠΎΡΡΡ ΠΊΠΎΠΌΠΏΠ»Π΅ΠΊΡΠ½ΠΎΠΉ ΠΎΡΠ΅Π½ΠΊΠΈ ΡΡΠ΅ΠΏΠ΅Π½ΠΈ ΠΏΠΎΠ²ΡΠ΅ΠΆΠ΄Π΅Π½ΠΈΡ Π»Π΅Π³ΠΊΠΈΡ
, ΠΏΡΠΈΡΠΈΠ½ ΡΠ°Π·Π²ΠΈΡΠΈΡ ΠΈ ΡΡΠΆΠ΅ΡΡΠΈ Π΄ΡΡ
Π°ΡΠ΅Π»ΡΠ½ΠΎΠΉ Π½Π΅Π΄ΠΎΡΡΠ°ΡΠΎΡΠ½ΠΎΡΡΠΈ, ΠΈ, ΠΏΠΎ Π²ΠΈΠ΄ΠΈΠΌΠΎΠΌΡ, ΡΡΠΎΡΠ½Π΅Π½ΠΈΡ ΠΈ ΡΠ°ΡΡΠΈΡΠ΅Π½ΠΈΡ ΠΊΡΠΈΡΠ΅ΡΠΈΠ΅Π² ΠΏΠΎΡΡΠ°Π½ΠΎΠ²ΠΊΠΈ ΡΡΠΎΠ³ΠΎ Π΄ΠΈΠ°Π³Π½ΠΎΠ·Π°. ΠΠ»ΡΡΠ΅Π²ΡΠ΅ ΡΠ»ΠΎΠ²Π°: ΠΎΡΡΡΠΎΠ΅ ΠΏΠΎΠ²ΡΠ΅ΠΆΠ΄Π΅Π½ΠΈΠ΅ Π»Π΅Π³ΠΊΠΈΡ
, ΠΎΡΡΡΡΠΉ ΡΠ΅ΡΠΏΠΈΡΠ°ΡΠΎΡΠ½ΡΠΉ Π΄ΠΈΡΡΡΠ΅ΡΡ-ΡΠΈΠ½Π΄ΡΠΎΠΌ, ΠΎΡΡΡΠ°Ρ Π΄ΡΡ
Π°ΡΠ΅Π»ΡΠ½Π°Ρ Π½Π΅Π΄ΠΎΡΡΠ°ΡΠΎΡΠ½ΠΎΡΡΡ, ΠΈΠ½Π΄Π΅ΠΊΡ ΠΎΠΊΡΠΈΠ³Π΅Π½Π°ΡΠΈΠΈ
- β¦