Honeybee product therapeutic as stem cells homing for ovary failure

Aim: Complexity of the method of isolation, cultivation in vitro and the expensive cost of transplantation process of stem cells, it would require an innovation to homing and differentiation of stem cells and increase folliculogenesis. The stem cells homing was achieved through the provision of food or beverages derived from natural materials like honeybee product. Through honeybee product, there will be homing of stem cells and accompany with the sources from the body itself will take place in regeneration of the ovary. Materials and Methods: Female rats model of degenerative ovary was obtained through food fasting but still have drinking water for 5 days. It caused malnutrition and damage of the ovarian tissue. The administration of 50% honeybee product (T1) was performed for 10 consecutive days, while the positive control group (T0+) was fasted and not given honeybee product and the negative control (T0−) not fasted and without honeybee product. Observations were taken for homing of stem cells, raised of folliculogenesis, differentiation of stem cells, and regeneration of the ovarian tissue using routine H&E staining. Results: Homing of stem cells shown the vascular endothelial growth factor and granulocyte colony-stimulating factor expression; enhancement of folliculogenesis was indicated by an increase of follicle dee Graaf count; enhancement of differentiation of stem cells was indicated by growth differentiation factor-9 expression; and regeneration of ovarian tissue indicated by intact ovarian tissue with growing follicles. Conclusion: Honeybee product can be induced endogenous stem cells in regeneration of ovary failure due to malnutrition

Pelatihan Strategi Pemasaran Produk Bagi Calon Wirausahawan Muda untuk Mahasiswa Semester Akhir Universitas Mathlaul Anwar, Pandeglang

Pandemi COVID-19 yang telah berlangsung hampir 10 bulan di tahun 2020 ini, secara nyata berdampak pada perekonomian negara negara di dunia termasuk Indonesia. Telah menjadi fakta bahwa kemampuan Perusahaan semakin kurang menyerap tenaga kerja sementara jumlah para pencari kerja semakin bertambah.  Kegiatan pengabdian kepada masyarakat ini bertujuan untuk memberikan inspirasi kreativitas usaha, memperkenalkan strategi pemasaran produk serta menginisiasi kelahiran wirausahawan muda di kalangan mahasiswa tingkat akhir di Universitas Mathla'ul Anwar, Pandeglang. Pelatihan ini dilaksanakan melalui zoom sebagai media penyampai secara daring karena waktu pelaksanaan bersamaan dengan berlakunya PSBB di wilayah Banten. Materi pelatihan yang disampaikan adalah konsep pemasaran produk, berbagai jenis pemasaran, fungsi pemasaran dan strategi pemasaran produk. Dari hasil angket yang dibagikan sebelum dan sesudah kegiatan,  para peserta lebih memahami berbagai strategi pemasaran produk. Kendala yang dialami selama pelaksanaan acara adalah jaringan internet yang tidak stabil. PKM kewirausahaan lanjutan sebaiknya menghadirkan wirausahawan yang berpengalaman lapangan, sehingga peserta mendapatkan referensi lebih mengarah pada alternatif pemecahan masalah

Validasi Metode Penetapan Kadar Vitamin C Kulit Jeruk Keprok (Citrus Reticulata) secara Spekteofotometri UV-Vis

Banyaknya tanaman yang berkhasiat sebagai obat menjadikan pengobatan tradisional menjadi salah satu pilihan terapi yang banyak digunakan. Salah satunya adalah pemanfaatan kulit jeruk keprok (Citrus reticulata) yang mengandung vitamin C. Adanya peningkatan jumlah penelitian tentang kulit jeruk keprok, utamanya mengenai modifikasi dalam sediaan farmasi, menyebabkan dibutuhkannya validasi metode analisis untuk memastikan jaminan mutu sebuah produk. Tujuan dari penelitian ini adalah melakukan validasi penetapan kadar vitamin C dari ekstrak kulit jeruk keprok secara spektrofotometri UV-Vis. Kulit jeruk keprok dimaserasi menggunakan etanol 70%. Kadar vitamin C ekstrak kulit jeruk diukur absorbansinya menggunakan spektrofotometri UV-Vis pada panjang gelombang 274,2 nm. Validasi metode analisis dilakukan dengan menghitung nilai linieritas, presisi, akurasi, batas deteksi, dan batas kuantifikasi. Berdasarkan penelitian dihasilkan persamaan y=0,069x–0,01 dengan nilai r=0,999, presisi dengan nilai RSD<2%, perolehan kembali pada rentang 97,91-104,16%, batas deteksi 0,239 ppm, dan batas kuantifikasi 0,724 ppm. Kadar vitamin C pada ekstrak kulit jeruk keprok adalah 51,88 mg/g. Hasil penelitian menunjukkan bahwa metode analisis penetapan kadar vitamin C dengan spektrofotometri UV-Vis telah memenuhi parameter validasi analisis

The Transferability of Health Promotion and Education Approaches Between Non-communicable Diseases and Communicable Diseases—an Analysis of Evidence

Background: There is a seeming lack within the public health fields of both research and practice of information sharing across so-called “silos of work”. Many professionals in the public health fields dealing with infectious diseases (IDs) are unaware of the programs and approaches taken by their colleagues in the non-communicable diseases (NCDs) arena, and vice versa. A particular instance of this is in the understanding and application of health promotion approaches. This is a problem that needs to be addressed with the goal of producing the most efficient and effective health promotion approaches to the prevention and control of diseases in general. Objectives: This project examined health promotion approaches to the prevention of NCDs that could be used in the prevention of IDs. Methods: A knowledge synthesis and translation perspective was undertaken. We screened and analyzed a wide range of sources that were considered relevant, with particular emphasis on systematic reviews, published articles and the grey literature. Results: The analysis revealed a diverse health promotion knowledge base for application to IDs. Comprehensive health promotion models were found to be useful. Findings suggest that there are profound similarities for health promotion approaches in both NCDs and IDs. Conclusions: This study revealed gaps in knowledge synthesis to translation. The need for development of intervention and implementation research is considered

A health promotion approach to emergency management: effective community engagement strategies from five cases.

Community engagement is crucial for controlling disease outbreak and mitigating natural and industrial disasters. The COVID-19 pandemic has reconfirmed the need to elevate community engagement to build equity, trust and sustained action in future health promotion preparedness strategies. Using the health promotion strategy of strengthening community action enhances the opportunity for better outcomes. There is, therefore, a need to improve our understanding of community engagement practices during crises, scale-up good community engagement initiatives, and improve and sustain people-centered approaches to emergency responses. This paper presents five case studies from the United States, Singapore, Sierra Leone, Kenya and South Africa that demonstrate the potential strengths that can be nurtured to build resilience in local communities to help mitigate the impact of disasters and emergencies. The case studies highlight the importance of co-developing relevant education and communication strategies, amplifying the role of community leaders, empowering community members to achieve shared goals, assessing and adapting to changing contexts, pre-planning and readiness for future emergencies and acknowledgement of historic context