A tool for subjective and interactive visual data exploration

We present SIDE, a tool for Subjective and Interactive Visual Data Exploration, which lets users explore high dimensional data via subjectively informative 2D data visualizations. Many existing visual analytics tools are either restricted to specific problems and domains or they aim to find visualizations that align with user’s belief about the data. In contrast, our generic tool computes data visualizations that are surprising given a user’s current understanding of the data. The user’s belief state is represented as a set of projection tiles. Hence, this user-awareness offers users an efficient way to interactively explore yet-unknown features of complex high dimensional datasets

Time dilation in relativistic two-particle interactions

We study the orbits of two interacting particles described by a fully relativistic classical mechanical Hamiltonian. We use two sets of initial conditions. In the first set (dynamics 1) the system\u27s center of mass is at rest. In the second set (dynamics 2) the center of mass evolves with velocity V. If dynamics 1 is observed from a reference frame moving with velocity-V, the principle of relativity requires that all observables must be identical to those of dynamics 2 seen from the laboratory frame. Our numerical simulations demonstrate that kinematic Lorentz space-time transformations fail to transform particle observables between the two frames. This is explained as a result of the inevitable interaction dependence of the boost generator in the instant form of relativistic dynamics. Despite general inaccuracies of the Lorentz formulas, the orbital periods are correctly predicted by the Einstein\u27s time dilation factor for all interaction strengths

Upward Three-Dimensional Grid Drawings of Graphs

A \emph{three-dimensional grid drawing} of a graph is a placement of the vertices at distinct points with integer coordinates, such that the straight line segments representing the edges do not cross. Our aim is to produce three-dimensional grid drawings with small bounding box volume. We prove that every $n$-vertex graph with bounded degeneracy has a three-dimensional grid drawing with $O(n^{3/2})$ volume. This is the broadest class of graphs admiting such drawings. A three-dimensional grid drawing of a directed graph is \emph{upward} if every arc points up in the z-direction. We prove that every directed acyclic graph has an upward three-dimensional grid drawing with $(n^3)$ volume, which is tight for the complete dag. The previous best upper bound was $O(n^4)$. Our main result is that every $c$-colourable directed acyclic graph ($c$ constant) has an upward three-dimensional grid drawing with $O(n^2)$ volume. This result matches the bound in the undirected case, and improves the best known bound from $O(n^3)$ for many classes of directed acyclic graphs, including planar, series parallel, and outerplanar

Socioeconomic inequalities in health among Swedish adolescents - adding the subjective perspective

Abstract Background Socioeconomic inequalities in adolescent health predict future inequalities in adult health. Subjective measures of socioeconomic status (SES) may contribute with an increased understanding of these inequalities. The aim of this study was to investigate socioeconomic health inequalities using both a subjective and an objective measure of SES among Swedish adolescents. Method Cross-sectional HBSC-data from 2002 to 2014 was used with a total sample of 23,088 adolescents aged 11–15 years. Three measures of self-rated health (dependent variables) were assessed: multiple health complaints, life satisfaction and health perception. SES was measured objectively by the Family Affluence Scale (FAS) and subjectively by “perceived family wealth” (independent variables). The trend for health inequalities was investigated descriptively with independent t-tests and the relationship between independent and dependent variables was investigated with multiple logistic regression analysis. Gender, age and survey year was considered as possible confounders. Results Subjective SES was more strongly related to health outcomes than the objective measure (FAS). Also, the relation between FAS and health was weakened and even reversed (for multiple health complaints) when subjective SES was tested simultaneously in regression models (FAS OR: 1.03, CI: 1.00;1.06 and subjective SES OR: 0.66, CI: 0.63;0.68). Conclusions The level of socioeconomic inequalities in adolescent health varied depending on which measure that was used to define SES. When focusing on adolescents, the subjective appraisals of SES is important to consider because they seem to provide a stronger tool for identifying inequalities in health for this group. This finding is important for policy makers to consider given the persistence of health inequalities in Sweden and other high-income countries

LARP7 family proteins have conserved function in telomerase assembly

Understanding the intricacies of telomerase regulation is crucial due to the potential health benefits of modifying its activity. Telomerase is composed of an RNA component and reverse transcriptase. However, additional factors required during biogenesis vary between species. Here we have identified fission yeast Lar7 as a member of the conserved LARP7 family, which includes the Tetrahymena telomerase-binding protein p65 and human LARP7. We show that Lar7 has conserved RNA-recognition motifs, which bind telomerase RNA to protect it from exosomal degradation. In addition, Lar7 is required to stabilise the association of telomerase RNA with the protective complex LSm2-8, and telomerase reverse transcriptase. Lar7 remains a component of the mature telomerase complex and is required for telomerase localisation to the telomere. Collectively, we demonstrate that Lar7 is a crucial player in fission yeast telomerase biogenesis, similarly to p65 in Tetrahymena, and highlight the LARP7 family as a conserved factor in telomere maintenance

Stopping of Charged Particles in a Magnetized Classical Plasma

The analytical and numerical investigations of the energy loss rate of the test particle in a magnetized electron plasma are developed on the basis of the Vlasov-Poisson equations, and the main results are presented. The Larmor rotation of a test particle in a magnetic field is taken into account. The analysis is based on the assumption that the energy variation of the test particle is much less than its kinetic energy. The obtained general expression for stopping power is analyzed for three cases: (i) the particle moves through a collisionless plasma in a strong homogeneous magnetic field; (ii) the fast particle moves through a magnetized collisionless plasma along the magnetic field; and (iii) the particle moves through a magnetized collisional plasma across a magnetic field. Calculations are carried out for the arbitrary test particle velocities in the first case, and for fast particles in the second and third cases. It is shown that the rate at which a fast test particle loses energy while moving across a magnetic field may be much higher than the loss in the case of motion through plasma without magnetic field.Comment: 14 pages, 3 figures, LaTe

Present Status and Future Programs of the n_TOF Experiment

This is an Open Access article distributed under the terms of the Creative Commons Attribution-Noncommercial License 3.0, which permits unrestricted use, distribution, and reproduction in any noncommercial medium, provided the original work is properly citedThe neutron time-of-flight facility n_TOF at CERN, Switzerland, operational since 2001, delivers neutrons using the Proton Synchrotron (PS) 20 GeV/c proton beam impinging on a lead spallation target. The facility combines a very high instantaneous neutron flux, an excellent time of flight resolution due to the distance between the experimental area and the production target (185 meters), a low intrinsic background and a wide range of neutron energies, from thermal to GeV neutrons. These characteristics provide a unique possibility to perform neutron-induced capture and fission cross-section measurements for applications in nuclear astrophysics and in nuclear reactor technology.The most relevant measurements performed up to now and foreseen for the future will be presented in this contribution. The overall efficiency of the experimental program and the range of possible measurements achievable with the construction of a second experimental area (EAR-2), vertically located 20 m on top of the n_TOF spallation target, might offer a substantial improvement in measurement sensitivities. A feasibility study of the possible realisation of the installation extension will be also presented

Sunshine, rainfall, humidity and child pneumonia in the tropics: time-series analyses

Few studies have formally examined the relationship between meteorological factors and the incidence of child pneumonia in the tropics, despite the fact that most child pneumonia deaths occur there. We examined the association between four meteorological exposures (rainy days, sunshine, relative humidity, temperature) and the incidence of clinical pneumonia in young children in the Philippines using three time-series methods: correlation of seasonal patterns, distributed lag regression, and case-crossover. Lack of sunshine was most strongly associated with pneumonia in both lagged regression [overall relative risk over the following 60 days for a 1-h increase in sunshine per day was 0·67 (95% confidence interval (CI) 0·51–0·87)] and case-crossover analysis [odds ratio for a 1-h increase in mean daily sunshine 8–14 days earlier was 0·95 (95% CI 0·91–1·00)]. This association is well known in temperate settings but has not been noted previously in the tropics. Further research to assess causality is needed

Measurement of the 12C(n,p)12B cross section at n-TOF at CERN by in-beam activation analysis

The integral cross section of the 12C(n,p)12B reaction has been determined for the first time in the neutron energy range from threshold to several GeV at the n-TOF facility at CERN. The measurement relies on the activation technique with the β decay of 12B measured over a period of four half-lives within the same neutron bunch in which the reaction occurs. The results indicate that model predictions, used in a variety of applications, are mostly inadequate. The value of the integral cross section reported here can be used as a benchmark for verifying or tuning model calculations.Peer reviewedFinal Accepted Versio