Active self supplied AC-DC converter for piezoelectric energy scavenging systems with supply independent bias

Abstract- The paper focuses on an electronic interface which can be used into Piezoelectric Energy Scavenging Systems (PESS). These systems convert the energy of mechanical vibrations into electrical energy using a piezoelectric transducer to realize a power supply for low power electronic systems. To obtain a suitable supply source an AC-DC conversion of the output signal of these transducers is needed and, since the output power level of the energy scavenger can be very low, the conversion should be as efficient as possible. This paper shows an active voltage doubler AC-DC converter for PESSs. A novel driving circuitry topology is presented; it has the advantage to be tolerant with respect to the process variations. The converter uses exclusively a fraction of the harvested energy to supply itself and a bias circuit has been designed to make the total current consumption supply independent. The simulation results show that the efficiency of the AC-DC converter can be as high as 94%. The circuit will be diffused in 0.35µm CMOS STMicroelectronics technology. I

Mechanisms of HIV-associated lymphocyte apoptosis: 2010

The inevitable decline of CD4T cells in untreated infection with the Human immunodeficiency virus (HIV) is due in large part to apoptosis, one type of programmed cell death. There is accumulating evidence that the accelerated apoptosis of CD4T cells in HIV infection is multifactorial, with direct viral cytotoxicity, signaling events triggered by viral proteins and aberrant immune activation adding to normal immune defense mechanisms to contribute to this phenomenon. Current antiviral treatment strategies generally lead to reduced apoptosis, but this approach may come at the cost of preserving latent viral reservoirs. It is the purpose of this review to provide an update on the current understanding of the role and mechanisms of accelerated apoptosis of T cells in the immunopathogenesis of HIV infection, and to highlight potential ways in which this seemingly deleterious process could be harnessed to not just control, but treat HIV infection

The role of mechanical ventilation for efficient radiant cooling in residential applications

The request of summer air conditioning in dwellings is continuously increasing in many countries for comfort reasons. This trend brings about two important problems: how to cope with the energy saving and CO2 emissions and, on the other hand, how to achieve the goal by means of simple and effective plants. The use of radiant systems, especially ceiling ones, can represent a good solution if the building is correctly sheltered from solar gains, suitably insulated and the internal gains are controlled. On the other hand, the risk of reaching surfaces temperatures below dew point with consequent condensations, can limit the application of this technology. In this regard the use of mechanical controlled ventilation with cooling and dehumidification of air contributes to a larger application of radiant systems. A detailed simulation model has been set up to investigate the applicability and limits of different solutions, referring to climatic data (TRY) for various locations in southern Europe

A nano-power energy harvesting IC for arrays of piezoelectric transducers

This paper describes a multi-source energy harvester IC for arrays of independent transducers, designed in a 0.32um STMicroelectronics BCD technology, that can manage up to 5 AC-DC channels (e.g. piezoelectric transducers). The IC implements a boost converter based on synchronous electrical charge extraction. A single external inductor is time-shared among all transducers and access conflicts are handled by an arbiter circuit implemented as an asynchronous FSM. The converter is fully autonomous and suitable for battery-less operation. The circuit area is 4.6 mm^2 and has a power consumption of 175 nW/source at 2.5 V while efficiency ranges between 70% and over than 85%

Cardiomyocytes undergo apoptosis in human immunodeficiency virus cardiomyopathy through mitochondrion- and death receptor-controlled pathways

We investigated 18 AIDS hearts (5 with and 13 without cardiomyopathy) by using immunocytochemistry and computerized image analysis regarding the roles of HIV-1 proteins and tumor necrosis factor ligands in HIV cardiomyopathy (HIVCM). HIVCM and cardiomyocyte apoptosis were significantly related to each other and to the expression by inflammatory cells of gp120 and tumor necrosis factor-α. In HIVCM heart, active caspase 9, a component of the mitochondrion-controlled apoptotic pathway, and the elements of the death receptor-mediated pathway, tumor necrosis factor-α and Fas ligand, were expressed strongly on macrophages and weakly on cardiomyocytes. HIVCM showed significantly greater macrophage infiltration and cardiomyocyte apoptosis rate compared with non-HIVCM. HIV-1 entered cultured neonatal rat ventricular myocytes by macropinocytosis but did not replicate. HIV-1- or gp120-induced apoptosis of rat myocytes through a mitochondrion-controlled pathway, which was inhibited by heparin, AOP-RANTES, or pertussis toxin, suggesting that cardiomyocyte apoptosis is induced by signaling through chemokine receptors. In conclusion, in patients with HIVCM, cardiomyocytes die through both mitochondrion- and death receptor-controlled apoptotic pathways