Ways to Reduce Water Erosion on Mountainous Slope Lands

The most important problem in the highland area is the development of technologies to reduce water erosion and improve soil fertility preservation. In order to restore degraded soils of slope lands, a number of measure is undertaken, among them planting crops across the slope and rational fertilizer treatment. To reduce erosion processes, mineral fertilizers were applied depending on the steepness of slope. High sections with the steepness of 9–10∘ received ammonium sulphate in a quantity of 60 kg/ha. Lower part of the slope with the steepness of 5–7∘ received ammonia nitrate as a nitrogen fertilizer in a quantity of 80 kg/ha, while the gentle sloping part with 2–5∘ had urea-formaldehyde fertilizer incorporated under winter tillage in a quantity of 50 kg/ha. At that, stripes were formed across the slope where tall-growing perennial herbs were planted: hill mustard (Bunias orentalis L.), silphium (Silphium perfaliatum), Eastern galega (Galeqa orientalis L.), cock’s foot grass (Dakfilis qlamerata L.). The research results have shown that thanks to fertilizers, yield of crops increases by a factor of 1.5–2, while soil losses reduced from 0.042 to 0.018 t/ha

Accessing new physics with an undoped, cryogenic CsI CEvNS detector for COHERENT at the SNS

We consider the potential for a 10-kg undoped cryogenic CsI detector operating at the Spallation Neutron Source to measure coherent elastic neutrino-nucleus scattering and its sensitivity to discover new physics beyond the standard model. Through a combination of increased event rate, lower threshold, and good timing resolution, such a detector would significantly improve on past measurements. We considered tests of several beyond-the-standard-model scenarios such as neutrino non-standard interactions and accelerator-produced dark matter. This detector's performance was also studied for relevant questions in nuclear physics and neutrino astronomy, namely the weak charge distribution of CsI nuclei and detection of neutrinos from a core-collapse supernova

Targeting poly(ADP-ribose) polymerase activity for cancer therapy

Poly(ADP-ribosyl)ation is a ubiquitous protein modification found in mammalian cells that modulates many cellular responses, including DNA repair. The poly(ADP-ribose) polymerase (PARP) family catalyze the formation and addition onto proteins of negatively charged ADP-ribose polymers synthesized from NAD+. The absence of PARP-1 and PARP-2, both of which are activated by DNA damage, results in hypersensitivity to ionizing radiation and alkylating agents. PARP inhibitors that compete with NAD+ at the enzyme’s activity site are effective chemo- and radiopotentiation agents and, in BRCA-deficient tumors, can be used as single-agent therapies acting through the principle of synthetic lethality. Through extensive drug-development programs, third-generation inhibitors have now entered clinical trials and are showing great promise. However, both PARP-1 and PARP-2 are not only involved in DNA repair but also in transcription regulation, chromatin modification, and cellular homeostasis. The impact on these processes of PARP inhibition on long-term therapeutic responses needs to be investigated

Glacier Kolka Collapse on September 20, 2002 in North Ossetia

Based on the processing of digital instrumental recordings, the main stages of the Kolka glacier (North Ossetia) collapse process were defined. 15 special points of the collapse process were identified in digital recordings. In addition, the main movement stages of the ice-rock mass were clarified on the basis of seismological data. Based on the detailed analysis, the velocities and accelerations at different stages were estimated and the nature of changes in velocities and accelerations caused by the features of the terrain relief (slope steepness, cross-section) along the movement path was determine

Ways to Reduce Water Erosion on Mountainous Slope Lands

The most important problem in the highland area is the development of technologies to reduce water erosion and improve soil fertility preservation. In order to restore degraded soils of slope lands, a number of measure is undertaken, among them planting crops across the slope and rational fertilizer treatment. To reduce erosion processes, mineral fertilizers were applied depending on the steepness of slope. High sections with the steepness of 9–10∘ received ammonium sulphate in a quantity of 60 kg/ha. Lower part of the slope with the steepness of 5–7∘ received ammonia nitrate as a nitrogen fertilizer in a quantity of 80 kg/ha, while the gentle sloping part with 2–5∘ had urea-formaldehyde fertilizer incorporated under winter tillage in a quantity of 50 kg/ha. At that, stripes were formed across the slope where tall-growing perennial herbs were planted: hill mustard (Bunias orentalis L.), silphium (Silphium perfaliatum), Eastern galega (Galeqa orientalis L.), cock's foot grass (Dakfilis qlamerata L.). The research results have shown that thanks to fertilizers, yield of crops increases by a factor of 1.5–2, while soil losses reduced from 0.042 to 0.018 t/ha