Enhanced response of the regular networks to local signals in presence of a fast impurity

We consider an array of inductively coupled Josephson junctions with a fast impurity (a junction with a smaller value of critical current), and study the consequences of imposing a small amplitude periodic signal at some point in the array. We find that when external signal is imposed at the impurity, the response of the array is boosted and a small amplitude signal can be detected throughout the array. When the signal is imposed elsewhere, minor effects is seen on the dynamics of the array. The same results have been also seen in presence of a single fast spiking neuron in a chain of diffusively coupled FitzHugh-Nagumo neurons.Comment: 6 pages, 5 figures, arXiv admin note: substantial text overlap with arXiv:1108.460

An Investigation on Adoption of Socio-Culturally Based Teaching Strategies Among Iranian Clinical Nurse Educators

Background: In today’s complex healthcare environments, the traditional teaching strategies and learning models are unable to prepare learners to confront with rapid changes. Some education scholars believe that the teaching strategies based on socioculturally theory are more responsible and efficient. Objectives: The present study was conducted to investigate socio-culturally-based teaching strategies being adopted or assigned by Iranian clinical nurse educators as high priorities. Patients and Methods: A descriptive study was conducted on 38 nurse educators from two nursing and midwifery faculties in Tabriz and Urmia, Iran. Data were collected over a period of 2 months in 2010 using the Phillip’s Adoption Appraisal Instrument, developed by Bonk & Kim. The instrument items have been ranked on a 4-point Likert-type scale and ordered in 10 subscales. The data were analyzed using SPSS software version 13.0. The overall mean, standard deviation, and confidence interval 95% were calculated for each subscale to determine the rank distribution of subscales. Results: All strategies were known as a moderate adoption (2.72 ± 0.44 of 4), however prioritizing in adoption of socio-culturally-based teaching strategies from clinical nurse educators’ viewpoints indicated that 60% of strategies were evaluated as the most adopted strategies, 10% as the least, and the other 30% in moderate mode. Conclusions: Due to the importance of socio-culturally-based theory strategies in clinical settings and the moderate adoption of strategies from clinical nurse educators’ viewpoints,educational planners and policymakers should prepare required prepositions to progress the adoption and the usage of these strategies

Coping With Stress in Iranian School-Age Children

Background: Methods learnt by children to cope with stress will be used in their adolescence. Failure to learn adaptive coping strategies causes some mental, physical and behavioral problems which continue until adulthood. Objectives: The current study was conducted to investigate the methods of coping with stress among Iranian school-age children. Patients and Methods: A descriptive study was conducted in which a randomly selected sample of 839 students of third to fifth grade of primary school in Tabriz, Iran participated. The data were collected using the Schoolagers` Coping Strategies Inventory questionnaire. SPSS software was employed to analyze the data by percentage, absolute frequency, and linear regression test. Results: All coping methods inserted in the questionnaire were used by students. More than 70% of students mentioned “pray”, “say I’m sorry or tell the truth”, and “try to relax, stay calm” out of 26 cases of coping strategies. According to more than 60% of children, “pray”, “say I’m sorry or tell the truth”, and “draw, write, or read something” were the most useful coping methods and “pick on someone” and “yell or scream” were not mostly used by the children under study. Conclusions: Children use variable methods to cope with their stress. Therefore, parents, health trainers and school authorities should distinguish non-adaptive methods of children and teach them the adaptive coping strategies

The image of nursing, as perceived by Iranian male nurses

The stereotypical public image of nursing is a major concern for male nurses around the world. In this study, we explored how Iranian male nurses perceived the public view of nurses, and their perceptions of themselves. A qualitative descriptive design and content analysis were used to obtain data from 18 purposely-selected male hospital nurses with a baccalaureate nursing degree in Tabriz, Iran. Semistructured interviews were conducted and analyzed. Two main themes emerged: (i) the outsider's view of nursing, which referred to the participants' perceptions of their public image; and (ii) the insider's view, which related to the male nurses' perceptions of themselves. Results included personal transition into a positive professional self-image through the educational process, and continued public perception of nursing as a female profession ill-suited for a man. Strategies to improve the insider's and outsider's views of nursing are listed to help recruit and retain more Iranian male nurses

Organizational Activities in Nursing Research Transfer from Viewpoint of Nurse Educators in Iranian Universities of Medical Sciences

Background: Transferring research-based knowledge into practice would help to maximize the quality of health care. However, the role of knowledge producers and the organizational roles related to knowledge transfer have been largely ignored. Objectives: This study was accomplished with the aim of describing the organizational activities needed to transfer the findings of nursing research from the viewpoint of nurse educators in Iranian Universities of Medical Sciences. Patients and Methods: This descriptive study was carried out with participating 279 nurse educators of medical sciences universities. Data were collected using Knowledge Translation Self-Assessment Tool for Research Institutes (SATORI). Results: Nursing faculty members evaluated the organizational activities of transferring the knowledge of nursing research at the “medium” level and for the domains of “the question of research” and “promoting the use of evidence” at a “weak” level and in the domains of “knowledge production” and “knowledge transfer” at a “medium” level. Conclusions: Organizational activities related to the knowledge transfer of nursing research are demonstrably low (medium at best). It is recommended that in each faculty and with the participation of all faculty members, the research transferring procedure should be assessed and all necessary changes needed to improve the research transferring procedure should be implemented

Comparison of quadruple and triple Furazolidone containing regimens on eradication of helicobacter pylori

Background: The effectiveness of classic standard triple therapy regimen of helicobacter pylori (H. pylori) eradication has decreased to unacceptably low levels, largely related to development of resistance to metronidazole and clarithromycin. Thus successful eradication of H. pylori infections remains challenging. Therefore alternative treatments with superior effectiveness and safety should be designed and appropriately tested in all areas depending on the native resistance patterns. Furazolidone has been used successfully in eradication regimens previously and regimens containing furazolidone may be an ideal regimen. Methods: H. pylori infected patients with proven gastric or duodenal ulcers and /or gastric or duodenal erosions at Imam Khomeini Hospital in Sari/Northern Iran, were randomly allocated into three groups: group A (OABF) with furazolidone (F) (200 mg bid.), group B (OABM-F) metronidazole (M) (500 mg bid.) for the first five days, followed by furazolidone (F) (200 mg bid.) for the second five days and group C (OAF) with furazolidone (F) (200 mg tid.). Omeprazole (O) (20 mg bid.) and amoxicillin (A) (1000 mg bid.) were given in all groups; bismuth (B) (240 mg bid.) was prescribed in groups A&B. Duration of all eradication regimens were ten days. Eight weeks after treatment, a 14C-urea breath test was performed for evaluation of H. pylori eradication. Results: A total of 372 patients were enrolled in three groups randomly (124 patients in each group); 120 (97) patients in group A (OABF), 120 (97) in group B (OABM-F) and 116 (93) in group C (OAF) completed the study. The intention-to-treat eradication rates were 83.7 (95 CI= 77.3-90.4), 79.8 (95 CI= 72.6-87), and 84.6 (95 CI= 78.2-91.1) and per-protocol eradication rates were 86.6 (95 CI= 80.5-92.8), 82.5 (95 CI= 75.6-89.4), and 90.5 (95 CI= 85.1-95.9) for groups OABF, OABM-F, and OAF, respectively. No statistical significant differences were found in case of severe drug adverse effects between the above mentioned three groups (p> 0.05). The most common side effects, namely nausea and fever, occurred in all groups, but more frequently in group C (OAF) (p< 0.05). Conclusion: In developing countries such as Iran, furazolidone-based regimens can substitute clarithromycinbased regimens for H. pylori eradication because of a very low level of resistance, low cost and high effectiveness. Considering per-protocol eradication rate of ten days OAF regimen, and the acceptable limit of ninety percent, we recommend this regimen in developing countries such as Iran to be substituted of classic standard triple therapy. In order to minimize rare serious adverse effects, one week high dose OAF regimen should be taken into consideration in other studies

Subduction-related mafic to felsic magmatism in the Malayer-Boroujerd plutonic complex, western Iran

The Malayer–Boroujerd plutonic complex (MBPC) in western Iran, consists of a portion of a magmatic arc built by the northeast verging subduction of the Neo-Tethys plate beneath the Central Iranian Microcontinent (CIMC). Middle Jurassic-aged felsic magmatic activity in MBPC is manifested by I-type and S-type granites. The mafic rocks include gabbroic intrusions and dykes and intermediate rocks are dioritic dykes and minor intrusions, as well as mafic microgranular enclaves (MMEs). MBPC Jurassic-aged rocks exhibit arc-like geochemical signatures, as they are LILE- and LREE-enriched and HFSE- and HREE-depleted and display negative Nb–Ta anomalies. The gabbro dykes and intrusions originated from metasomatically enriched garnet-spinel lherzolite [Degree of melting (fmel) ~ 15%] and exhibit negative Nd and positive to slightly negative εHf(T) (+ 3.0 to − 1.6). The data reveal that evolution of Middle Jurassic magmatism occurred in two stages: (1) deep mantle-crust interplay zone and (2) the shallow level upper crustal magma chamber. The geochemical and isotopic data, as well as trace element modeling, indicate the parent magma for the MBPC S-type granites are products of upper crustal greywacke (fmel: 0.2), while I-type granites formed by partial melting of amphibolitic lower crust (fmel: 0.25) and mixing with upper crustal greywacke melt in a shallow level magma chamber [Degree of mixing (fmix): 0.3]. Mixing between andesitic melt leaving behind a refractory dense cumulates during partial crystallization of mantle-derived magma and lower crustal partial melt most likely produced MMEs (fmix: 0.2). However, enriched and moderately variable εNd(T) (− 3.21 to − 4.33) and high (87Sr/86Sr)i (0.7085–0.7092) in dioritic intrusions indicate that these magmas are likely experienced assimilation of upper crustal materials. The interpretations of magmatic activity in the MBPC is consistent with the role considered for mantle-derived magma as heat and mass supplier for initiation and evolution of magmatism in continental arc setting, elsewhere

Recipients' experiences after organ transplantation

Background: After organ transplantation, many patients have diverse experiences; they face many changes in the physical and emotional aspects of their life. Patients' understandings of the post-transplantation period influence their adaptation to the changes. There is a need to improving the knowledge of patients' unique experiences of post-transplantation period and the changes occur in their life. Objective: To explore the experiences of organ recipients in the post-transplantation period. Methods: In a qualitative research using a hermeneutical phenomenological approach, data were collected from April 2015 to June 2016. Participants were consisted of 15 patients who received organ chosen using a purposive sampling method. In-depth semi-structured interviews were held with them. The collected data were analyzed using Diekelmann's hermeneutical analysis approach. Results: The data analyses led to the development of 3 main themes and 17 subthemes as "back from the grave" with the subthemes of "organ as the God's deposit," "God as the source of life," and "new life" "chapter of prosperity" with the subthemes of "the spring of the body," "recovery," "peace and joy," "benevolent and good behavior," "renewal," "opportunity of being together again," "golden age," "positive perspective," "the sense of normality," "the return of health," and "spiritual evolution" and "the fall" with the subthemes of "a lack of energy," "the mirage of transplantation," and "hell on the earth." Conclusion: The patients had diverse experiences of the post-transplantation period, which varied from the feeling of exhilaration and youth to losing energy and the wish for not undertaking organ transplantation. © 2018, Iranian Society for Organ Transplantation

Recipients' experiences after organ transplantation

Background: After organ transplantation, many patients have diverse experiences; they face many changes in the physical and emotional aspects of their life. Patients' understandings of the post-transplantation period influence their adaptation to the changes. There is a need to improving the knowledge of patients' unique experiences of post-transplantation period and the changes occur in their life. Objective: To explore the experiences of organ recipients in the post-transplantation period. Methods: In a qualitative research using a hermeneutical phenomenological approach, data were collected from April 2015 to June 2016. Participants were consisted of 15 patients who received organ chosen using a purposive sampling method. In-depth semi-structured interviews were held with them. The collected data were analyzed using Diekelmann's hermeneutical analysis approach. Results: The data analyses led to the development of 3 main themes and 17 subthemes as "back from the grave" with the subthemes of "organ as the God's deposit," "God as the source of life," and "new life" "chapter of prosperity" with the subthemes of "the spring of the body," "recovery," "peace and joy," "benevolent and good behavior," "renewal," "opportunity of being together again," "golden age," "positive perspective," "the sense of normality," "the return of health," and "spiritual evolution" and "the fall" with the subthemes of "a lack of energy," "the mirage of transplantation," and "hell on the earth." Conclusion: The patients had diverse experiences of the post-transplantation period, which varied from the feeling of exhilaration and youth to losing energy and the wish for not undertaking organ transplantation. © 2018, Iranian Society for Organ Transplantation

Development and optimisation of spironolactone nanoparticles for enhanced dissolution rates and stability

Stable solid lipid nanoparticles (SLNs) and nanostructured lipid carriers (NLCs) formulations to enhance the dissolution rates of poorly soluble drug spironolactone (SP) were being developed. Probe ultra-sonication method was used to prepare SLNs and NLCs. All NLCs contained stearic acid (solid lipid carrier) and oleic acid (liquid lipid content), whereas, SLNs were prepared and optimised by using the solid lipid only. The particles were characterised in terms of particle size analysis, thermal behaviour, morphology, stability and in vitro release. The zeta sizer data revealed that the increase in the concentration of oleic acid in the formulations reduced the mean particle size and the zeta potential. The increase in concentration of oleic acid from 0 to 30% (w/w) resulted in a higher entrapment efficiency. All nanoparticles were almost spherically shaped with an average particle size of about ∼170 nm. The DSC traces revealed that the presence of oleic acid in the NLC formulations resulted in a shift in the melting endotherms to a higher temperature. This could be attributed to a good long-term stability of the nanoparticles. The stability results showed that the particle size remained smaller in NLC compared to that of SLN formulations after 6 months at various temperatures. The dissolution study showed about a 5.1- to 7.2-fold increase in the release of the drug in 2 h compared to the raw drug. Comparing all nanoparticle formulations indicated that the NLC composition with a ratio of 70:30 (solid:liquid lipid) is the most suitable formulation with desired drug dissolution rates, entrapment efficiency and physical stability