6 research outputs found
Circular pattern matching with k mismatches
- Author
- A Amir
- C Barton
- C Barton
- C Barton
- C Hazay
- CS Iliopoulos
- GM Landau
- Karl Bringmann
- Kimmo Fredriksson
- KR Abrahamson
- LAK Ayad
- LAK Ayad
- M Crochemore
- M Ružić
- MAR Azim
- ML Fredman
- P Bille
- P Gawrychowski
- P Gawrychowski
- R Grossi
- Raphael Clifford
- T Hirvola
- T Kociumaka
- V Palazón-González
- V Palazón-González
- V Palazón-González
- WI Chang
- Z Galil
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 10/07/2019
- Field of study
The k-mismatch problem consists in computing the Hamming distance between a pattern P of length m and every length-m substring of a text T of length n, if this distance is no more than k. In many real-world applications, any cyclic shift of P is a relevant pattern, and thus one is interested in computing the minimal distance of every length-m substring of T and any cyclic shift of P. This is the circular pattern m
NPR1 mediates a novel regulatory pathway in cold acclimation by interacting with HSFA1 factors
- Author
- A Lazaro
- A Locascio
- A Nishizawa
- A Saleh
- B Belda-Palazón
- BAT Adie
- C Perea-Resa
- C Zhao
- CC Carey
- D Kim
- D Yu
- DL Wathugala
- E Ruelland
- F Blanco
- H Cao
- H Shi
- HC Liu
- HJ Lee
- J English
- J Kilian
- J Shah
- J. LEVITT
- K Bharti
- K Lawton
- K Pihakaski-Maunsbach
- KD Scharf
- M González-Guzmán
- M Griffith
- M Hermann
- M Kinkema
- M Moreau
- MC Wildermuth
- MI Love
- PJ Seo
- Q Bu
- RP Birkenbihl
- S Huang
- S Lee
- Sa Bowling
- SH Spoel
- T Czechowski
- T Nakagawa
- T Tsutsui
- T Yoshida
- T Zeilmaker
- V Chinnusamy
- V Kriechbaumer
- W Fan
- WC Hon
- X Xue-Xuan
- X Zhang
- Y Hu
- Y Kadota
- Y Kim
- Y Nakai
- Y Tada
- Y Zhang
- YH Yeh
- ZQ Fu
- ZQ Fu
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study
Stereocontrolled Synthesis of Cyclic Ethers by Intramolecular Hetero-Michael Addition. 5. Synthesis of All Diastereoisomers of 2,3,5,6-Tetrasubstituted Tetrahydropyrans
- Author
- Aicher T. D.
- Allevi P.
- Alvarez E.
- Ando K.
- Bates H. A.
- Boivin T. L. B.
- Brandsma L.
- Caron M.
- Cohran V. M.
- Corey E. J.
- Corley D. G.
- Dawe R. D.
- Ellis S.
- Erickson K.
- Faulkner D.
- For
- González A. G.
- Gung B. W.
- Hori K.
- Hughes M. S.
- Johnston B. D.
- Keinan E.
- Kim S.
- Kozikowski A. P.
- Lin Y.-Y.
- Marine Toxins
- Martin S. F.
- Maurer B.
- Mitsunobu O.
- Moore R.
- Murata M.
- Murata M.
- Murata M.
- Nagai H.
- Nagaoka H.
- Nicolaou K. C.
- Nicolaou K. C.
- Painter G. R.
- Palazón J. M.
- Ramírez M. A.
- Rawling B. J.
- Rodríguez C. M.
- Sakemi S.
- Satake M.
- Schreiber S. L.
- Seebach D.
- Sharpless K. B.
- Shimizu Y.
- Smith P. W.
- Still W. C.
- Suzuki T.
- Tagirachi H.
- Wesley J. W.
- Yamamoto Y.
- Publication venue
- 'American Chemical Society (ACS)'
- Publication date
- Field of study
Inequalities in screening policies and perioperative protection for patients with acute appendicitis during the pandemic: Subanalysis of the ACIE Appy study
- Author
- A Alhazmi
- A Alsaleh
- A Amendola
- A Bandin
- A Bavikatte
- A Becaria
- A Boddy
- A Bondurri
- A Brillantino
- A C Leonetti
- A Cacurri
- A Caira
- A Castaldi
- A Cavero Ibiricu
- A Charalabopoulos
- A Chessa
- A Chowdary
- A Cihat Yildirim
- A Costanzi
- A Das
- A De Luca
- A de San Ildefonso
- A Dorismé
- A Elmabri
- A Ferronetti
- A Frontali
- A García-Granero
- A Giuliani
- A Guariniello
- A Ioannidis
- A Iossa
- A Iqbal
- A Isaac
- A J D Nacion
- A Khan
- A Kulkarni
- A Kumar
- A Kuvvetli
- A L E Pérez-Sánchez
- A Laharwal
- A Leppäniemi
- A Lucchi
- A M Alvarado Padilla
- A M Gonzalez-Ganso
- A M Minaya-Bravo
- A Marinis
- A Martínez Roldan
- A Mazzari
- A Mehraj
- A Mihailescu
- A Mittal
- A Moncada
- A Musig
- A Najar
- A Navarro
- A O Toure
- A Orengia
- A P Delli Bovi
- A Paz Yáñez
- A Peloso
- A Piano
- A Picciariello
- A Police
- A Porcu
- A Pouy
- A Prestera
- A Rahman Mitul
- A Ramirez-Gutierrez de Velasco
- A Ramos-De la Medina
- A Rashid
- A Rencuzogullari
- A Rocca
- A Romano
- A Sanjiva Ratnayake
- A Sanz Larrainzar
- A Sarriugarte Lasarte
- A Sartori
- A Smith
- A Solís-Peña
- A Sretenović
- A Tarasconi
- A Tornambè
- A Tromba
- A Tzivanakis
- A Urbistondo
- A Valle Rubio
- A Wani
- A Álvarez Martínez
- A-R Jamiri
- B Alkhafaji
- B Braccio
- B Calì
- B Creavin
- B de Andrés Asenjo
- B De Simone
- B Ielpo
- B Jovanovic
- B Jovanovic
- B K P Goh
- B Martin-Perez
- B Pascotto
- B Santiago Lopez
- B Sensi
- B Stubbs
- B Sánchez Pérez
- B Zavala Retes
- C A Fagundes
- C Arcudi
- C Biddau
- C Cerdán Santacruz
- C Chia
- C Chirico
- C Dammaro
- C De Lucia
- C Dominguez Paez
- C Folliero
- C Fung Chia
- C Gazia
- C Guerci
- C J Gómez Díaz
- C Kwan Kong
- C Lo Faro
- C Oliva
- C Ovalle Chao
- C Paranjape
- C Parise
- C Petrola
- C Reinke
- C Sánchez Rodriguez
- C Thomas
- C Vallicelli
- C Varela
- C Yánez Benítez
- D A Merlini
- D C Nicolaescu
- D Camacho
- D D E Zimmerman
- D D'Antonio
- D Delogu
- D G Maldonado-Pintado
- D Kalivaçi
- D Linardoutsos
- D M Ferguson
- D M Giusti
- D Mazingi
- D Moro-Valdezate
- D Murrone
- D Osilli
- D Parini
- D Pertile
- D Popowich
- D Rega
- D Russello
- D S Keller
- D Sasia
- D Souza Lima
- D Tarik
- D Vinci
- D Zigiotto
- E A Acuña Roa
- E Agastra
- E Aytac
- E Baili
- E Benzoni
- E Bourmpouteli
- E Cardamone
- E Colás-Ruiz
- E Del Pozo Andres
- E Douka
- E Erdas
- E Flores-Villalba
- E Foianini
- E Francone
- E Guaitoli
- E Kouroumpas
- E Laterza
- E Laviano
- E Licardie
- E Marra
- E Martin-Perez
- E Morales
- E Moscoso
- E Mpaili
- E Peña
- E Pinna
- E Pinotti
- E Ricciardi
- E Rodas
- E Rosso
- E Ruiz Ajs
- E Saladino
- E Samadov
- E Smith-Singares
- E Varo
- E Vaterlini
- E Zhao
- F Agresta
- F Alconchel
- F Balestra
- F Bianco
- F Blanco Antona
- F Bonilla
- F Burdió
- F Ceci
- F Cervantes Ramírez
- F Colombo
- F Cordera
- F Di Marzo
- F Fernandes
- F Ferrara
- F Gheza
- F L Ramos
- F Lancellotti
- F Lazzarin
- F Litta
- F Luna
- F Luvisetto
- F M Fernandez
- F M Navarro
- F Madrid
- F Maraska
- F Marino
- F Martini
- F Mastella
- F Medas
- F Mendoza-Moreno
- F Monge Vieira
- F Muñoz Flores
- F O Llinares
- F P Tropeano
- F Pardo Aranda
- F Pareja
- F Pata
- F Pizza
- F Quezada
- F Quezada
- F Romano
- F Rosa
- F Roscio
- F Saliu
- F Schlottmann
- F Taylor
- F Virdis
- G A Stavrou
- G Argenio
- G Armand Ugon
- G Arredondo Manrique
- G Bagaglini
- G Bellanova
- G Bislenghi
- G Bointas
- G Brisinda
- G Calini
- G Candilio
- G Casoni Pattacini
- G Chocarro Amatriaín
- G Colucci
- G De Nobili
- G De Paola
- G Di Grezia
- G Esposito
- G Faillace
- G Formisano
- G Frazzetta
- G Galiffa
- G Gallo
- G Gravante
- G Gravante
- G Gunadi
- G Herrera-Almario
- G Izzo
- G Kampouroglou
- G La Gumina
- G Lisi
- G Luglio
- G M Machain
- G M Palini
- G Machain
- G Marcucci
- G Martin-Martin
- G Martínez-Mier
- G Massaferro
- G Nari
- G Nastri
- G Nigri
- G Ortega
- G Pagano
- G Papadopoulos
- G Partida
- G Pellino
- G Pellino
- G Romeo
- G Sammy Necchi
- G Sinibaldi
- G Tebala
- G van Ramshorst
- G Vanni
- H Ahmed
- H Ahmed Khan
- H Calvo
- H Ebied
- H Faraj
- H Fathy
- H Hamilton
- H Nava
- H Nikaj
- H Ordas Macias
- H Solano
- H Sánchez Alarcón
- I A San Roman
- I Al-Najami
- I Balciscueta
- I Baltazar
- I Bernescu
- I Brito Toledo
- I Dogaru
- I Fidoshev
- I Giani
- I Hussain
- I Jaén Torrejimeno
- I M Cornejo Jurado
- I Martinez Rodriguez
- I Mora-Guzmán
- I Negoi
- I Neri
- I Ortega
- I Palomares
- I Reccia
- I Romic
- I Shari Russo
- I Villalabeitia Ateca
- I Vincente Rodríguez
- J A Diaz-Elizondo
- J A Medina Luque
- J A S Reyes
- J Abba
- J Ahmad Sofi
- J Bellido Luque
- J C Kenington
- J C Martín Del Olmo
- J C Salamea
- J Castell
- J Dziakova
- J Eduardo García-Flores
- J F Coronel Olivier
- J Gutierrez
- J H Herrera Kok
- J I Roldán Villavicencio
- J Krook
- J L Blas Laina
- J Lammel-Lindemann
- J M Jover Navalón
- J M Ordoñez
- J M Silva Rodrigues
- J Mak
- J Olivier
- J Pejanovic Jose Gustavo Parreira
- J Pereira Pinto
- J Rincón Pérez
- J Sagolsem
- J Salas Rodriguez
- J Salinas
- J T Castell Gómez
- J Y Jang
- K Beatson
- K Sahnan
- K Sherafgan
- K Yanaga
- L A Garcia Ruiz
- L Alvarez
- L Asim
- L Athanasios
- L Barrionuevo
- L Bonavina
- L Conti
- L Curella
- L De Martino
- L E Fregoso
- L F Cabrera
- L Farber
- L Ferrario
- L G Osoria
- L G Rodriguez
- L García-Bruña
- L Giavarini
- L Giordano
- L Goffredi
- L Gordini
- L Grande
- L J Kantun Gonzalez
- L Moletta
- L Ong
- L Pio
- L Poggi
- L Ponchietti
- L Siragusa
- L Sánchez-Guillén
- L Taglietti
- L Tallon-Aguilar
- L Tresierra
- M A F Ribeiro
- M A Hernandez Bartolome
- M A Raza
- M Angrisani
- M Arrigo
- M Artiles-Armas
- M Azfar
- M Bagnall
- M Bingol-Kologlu
- M Bisaccia
- M Bouhuwaish
- M Calussi
- M Campanelli
- M Caneda Mejia
- M Cannavò
- M Cannistrà
- M Catarci
- M Cañón Lara
- M Cereda
- M Cervellera
- M Conte
- M David
- M De Rosa
- M Di Martino
- M E Vaterlini
- M Elhadi
- M F Jiménez
- M Farina
- M Franceschilli
- M G Lolli
- M G Spampinato
- M García Domínguez
- M Giordano
- M Guraieb
- M Hasabelnabi
- M Hassan
- M I Bellini
- M Iacobone
- M Jimenez Gomez
- M Khan
- M Korkoman
- M Lemma
- M Lim
- M M Chiarello
- M Martínez
- M Maruccia
- M Montes Manrique
- M Montuori
- M Myat Thway
- M Nardi
- M Nicola
- M Odovic
- M Paniagua-Garcia-Señorans
- M Paterno
- M Pedraza Ciro
- M Pellicciaro
- M Pera
- M Perez Gonzalez
- M Peter
- M Pezzulo
- M Pisano
- M Podda
- M Podda
- M Prieto Calvo
- M Rodriguez-Lopez
- M Rottoli
- M Rutegård
- M S J Wilson
- M Salah Eldin Hassan
- M Salö
- M Serradilla-Martín
- M Shalaby
- M Silveri
- M Sotelo
- M Taha
- M Tahir
- M Tolonen
- M Torre
- M Treviño
- M U Younis
- M Uemura
- M Veroux
- M Viola
- M Vito Marino
- M Wilson
- M Zaieem
- M Zambrano Lara
- M Zulfiqar Ali
- M Zuluagua
- M Zuolo
- N A Dallas
- N Ahmed Fieturi
- N Allievi
- N Alselaim
- N Antonacci
- N Brito
- N Cillara
- N de'Angelis
- N Falco
- N Gica
- N Krystek
- N Loria
- N Machairas
- N N Dudi-Venkata
- N Ortega
- N Pecorelli
- N Petrucciani
- N Pinto
- N Quazi
- N Smart
- N Tamini
- N Trelles
- N Villan Ramírez
- N Win Than
- O Alsherif
- O Avila Mercado
- O Bozbiyik
- O Hernández Palmas
- O I Hernandez Palmas
- O Ioannidis
- O Irkorucu
- O Sanz Guadarrama
- O Valles
- P A Najar Castañeda
- P Abadía-Barnó
- P Ajawin
- P Andrade
- P Baroffio
- P Campenni
- P Chiarade
- P Di Fronzo
- P Favoriti
- P Major
- P Marsanic
- P Mifsut
- P O Sillas Arevalos
- P Omelanczuk
- P Ottolino
- P Palazón Bellver
- P Panaccio
- P Prieto Olivares
- P Rodrigues
- P Ruiz
- P Sendino
- P Soon Koh
- P Souza
- P Talento
- P Wintringer
- R Angelico
- R Azar
- R Bessa Melo
- R Brady
- R Carrera-Ceron
- R Caruso
- R Caruso
- R Dholakia
- R Ebrahiminia
- R Faccincani
- R Fajardo
- R J Davies
- R Kashyap
- R Lim
- R Lozito
- R Lui
- R López Murga
- R M Isernia
- R Madariaga Pareja
- R Mohan Khattar
- R Peltrini
- R Pirolo
- R Rattan
- R Singh Bali
- R Singhal
- R Tejos
- R Tutino
- S A Parra
- S A Weckmann Luján
- S Amore Bonapasta
- S Awad
- S Benli
- S Cetinkunar
- S Chiappetta
- S Cárdenas
- S Delis
- S Dessureault
- S Di Saverio
- S Di Saverio
- S Flores
- S Fuentes
- S Garbarino
- S García
- S Gentilli
- S Gortazar de Las Casas
- S Grimaldi
- S Junaid
- S Keswani
- S Limon Suarez
- S M Ali
- S M Chan
- S Mansour
- S Monetti
- S Morales-Conde
- S Nabi
- S Napetti
- S Olivares Pizarro
- S Ortiz de Guzmán
- S Pérez-Bertólez
- S Rausei
- S Rojas
- S Salvans
- S Santoni
- S Scaringi
- S Shaw
- S Tayar
- S Tenconi
- T Alpha Oumar
- T Barnes
- T Brown
- T Calderon Duque
- T Campagnaro
- T Daskalakis
- T De Campos
- T E González
- T Elosua
- T Koëter
- T L D Fung
- T Liakakos
- T Liakakos
- T Luoto
- T N López
- T Perra
- T Rawashdeh
- T Zalla
- U Bracale
- U Giustizieri
- U Grossi
- U Rivas
- V Andriola
- V Balassone
- V Bellato
- V Carroni
- V Cavallaro
- V Celentano
- V Cordeiro Fonseca
- V De Simone
- V Dowling
- V Graham
- V H García Orozco
- V Jimenez Carneros
- V Luraschi
- V Papagni
- V Primo Romaguera
- V Progno
- V Rachkov
- V Raju
- V Rao Katta
- V Sosa
- V Testa
- V Tonini
- V Turrado-Rodriguez
- V Vigorita
- V Visag-Castillo
- W F Powers
- W Gonçalves
- W Grigg
- W O Bechstein
- Y Altinel
- Y B Lim
- Z Balciscueta
- Z Golubović
- Publication venue
- 'Oxford University Press (OUP)'
- Publication date
- 01/01/2021
- Field of study
Impacts of Use and Abuse of Nature in Catalonia with Proposals for Sustainable Management
- Author
- Aparicio Enric
- Arús i Gorina Pere
- Basnou Corina
- Blanché i Vergés Cèsar
- Bonada i Caparrós Núria
- Canals Purificació
- Capodiferro Marco
- Carceller Roqué Xavier
- Casademunt Àlex
- Casals Missio Joan
- Casals Pere
- Casañas F. (Francesc)
- Catalán i Aguilà Jordi
- Checa Joan
- Cordero Pedro J.
- Corominas Joaquim
- Espelta Morral Josep Maria
- Estrada i Miyares Marta
- Folch Ramon
- Franquesa Teresa
- Garcia-Lozano Carla
- Garí Mercè
- Geli Anna M.
- Germain i Otzet Josep
- González-Guerrero Óscar
- Gordillo Javier
- Gosàlbez i Noguera Joaquim
- Grimalt Obrador Joan
- Guàrdia Anna
- Isern Rosó
- Jordana i Vidal Jordi
- Junqué Eva
- Lascurain i Golferichs Josep
- Lleonart Jordi
- Llorente Gustavo A.
- Lloret Romañach Josep
- Lloret Francisco
- Mallarach Josep Maria
- Martín Vide Javier
- Medir i Huerta Rosa M.
- Melero Cavero Yolanda
- Montasell i Dorda Josep
- Montori Albert
- Munné Antoni (Munné i Torras)
- Nel·lo Oriol
- Palazón Santiago
- Palmero Marina
- Parés Margarida
- Peñuelas Josep
- Pino i Vilalta Joan
- Pintó i Fusalba Josep
- Planagumà Llorenç
- Pons Xavier
- Prat i Fornells Narcís
- Puig i Civera Carme
- Puig Ventosa Ignasi
- Puigdomènech Pere
- Pujol Buxó Eudald
- Roca Pascual Núria
- Rodrigo Jofre
- Rodríguez Teijeiro José Domingo
- Roig i Munar Francesc Xavier
- Romanyà i Socoró Joan
- Rovira Pere
- Sauras Yera Teresa
- Serrat David
- Simó Joan
- Soler Insa Jordi
- Sostoa Fernández Adolfo de
- Sàez Llorenç
- Terradas Jaume
- Vallejo V. Ramón (Victoriano Ramón)
- Vicente Paloma
- Vilaplana Joan Manuel
- Vinyoles Cartanyà Dolors
- Álvarez Domínguez Enrique
- Publication venue
- 'MDPI AG'
- Publication date
- Field of study
Evolution over Time of Ventilatory Management and Outcome of Patients with Neurologic Disease∗
- Author
- Abderrahim Azzouzi
- Abroug F.
- Achille Kouatchet
- Achim Lunkeit
- Adam Mikstacki
- Aguilera García
- Ahmed Sbihi
- Ai-Chin Cheng
- Ainhoa Rosselló
- Alain Mercat
- Alan Javier Zazu
- Alberto Belenguer
- Alberto Deicas
- Alberto Marino
- Alberto Soler
- Alejandro Algora
- Alejandro Arroliga
- Alejandro de la Serna
- Alejandro Gómez
- Alejandro Raimondi
- Alejandro Risso
- Alfonso Moreno
- Alfonso Muñoz
- Alfredo Padrón
- Alfredo Vasquez-Sandoval
- Ali Aydım Altunkan
- Ali Zeggwagh A.
- Aline Camile Yehia
- Alistair Nichol
- Allan Walkey
- Allison Bone
- Aloísio Marques do Nascimento
- Alvaro van Bommel
- Amalia Martínez de la Gandara
- Amber Monson
- Ambrogio Sansone
- Amee Patrawalla
- Amin P.
- Amine Ali Zeggwagh
- Amparo Ferrandiz
- Amy Waters
- Ana Carolina Caballero
- Ana Esther Trujillo
- Ana Villagrá
- Anders Aneman
- Andrea Gimenez
- Andrea Matte
- Andrea Neville Cracchiolo
- Andreas Schwartz
- Andreas Viehöfer
- Andrei Piontek
- Andrew Bersten
- Andrew Davies
- Andrew Davies
- Andrew Davies
- Andrew Steel
- Andrey Yaroshetskiy
- Anette Mortensen
- Anitha Shenoy
- Ankur Devendra Bhavsar
- Annunziata Mattei
- Anthony Saleh
- Antonina Pigna
- Antonino Giarratano
- Antonio Anzueto
- Antonio Braschi
- Antonio Corcione
- Antonio García-Jiménez
- Antonio Maestre
- Antonio Pesenti
- Antonio Raso
- Antonio Reyes
- Antonio Villa Delgado
- Antonio Viñuales
- Anzueto A.
- Arianna Boggero
- Ariel Chena
- Armando Pedulla'
- Arnaud W Thille
- Ashley Ellis
- Ashley Ellis
- Asisclo J Villagómez Ortiz
- Auke Reidinga
- Ayed Samia
- Barbara Tamowicz
- Barrios D.
- Bas M Kors
- Begoña Balerdi
- Benoit Veber
- Bernabé Álvarez
- Bersten A.
- Bert Beishuizen
- Besbes Mohamed
- Bilge Çetin
- Bin Du
- Bin Du
- Bin Yu
- Bing Sun
- Birgitte Viebaek
- Bladimir Alejandro Gil
- Bo Broberg
- Bo Wang
- Boris Villamagua
- Brian Sherman
- Bruno Bonaccorsi Fernandino
- Bruno do Valle Pinheiro
- Bryan Beatty
- C Canevet
- Cakar N.
- Cameron Knott
- Camilo Pizarro
- Carlo Alberto Acosta
- Carlos Alberto Studart Gomes
- Carlos André Correia Casado
- Carlos Andrés Díaz
- Carlos Gallego
- Carlos Marian Crespo
- Carlos Robles-Arias
- Carmelo Dueñas
- Carmen Campos
- Carolina Gímenez-Esparza
- Carolina Lorencio
- Cartan Costello
- Catherine Simmonds
- Cayce Strength
- Cayetano Galetti
- Cecilia Carbayo
- Cecilia Hermosa
- Cecilia Pereyra
- Cesar Enciso
- Cezar Mihailescu
- Chabu Coronado
- Chafrina Marie Olay
- Chang Liu
- Chantal Hogan
- Charki Haimeur
- Chau Chin Man
- Chen Chin-Ming
- Chengmin Yu
- Cheromi Sittambalam
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- Géraldine Dessertaine
- Haibo Qiu
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- Hong Pu
- Hongyang Xu
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- Jin Hwa Lee
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- Joyce Okahashi
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- Liliana Caipe
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- Samir Sahu
- Samir Vermani
- Sando Chavarria
- Sangeeta Mehta
- Sanjay Dhanuka
- Santiago Ilutovich
- Sara Cabañes
- Schimdt Alejandra
- Sebastian Circo
- Sebastián E Mare
- Serena Azzari
- Serge Heines
- Sergio Cáceres
- Sergio Lasdica
- Seton Henderson
- Shawna Reddie
- Sheila Nainan Myatra
- Shelby Sutton
- Sheree Gare
- Shirley Nelson
- Shouhong Wang
- Silke Frenzel
- Silvia Mareque
- Silvina Borello
- Silvio A Ñamendys-Silva
- Simon J G Hockley
- Simona Beniczky
- Sindhaghatta Venkatram
- Sine Wichman
- Smyth Smith
- Soares M. A.
- Sofía García
- Soraya Puertas
- Srinivas Samavedam
- Stambouli Neji
- Steffen Appel
- Steffen Weber-Carstens
- Stephanie Lubchansky
- Stephen Lapinsky
- Steven Y Chang
- Stevens Salva
- Subhash Kumar Todi
- Sujoy Mukherjee
- Susan Gillen
- Susana Alves Ferreira
- Susana Moradillo
- Susana Temprano
- Susanne Andi Iversen
- Sutherasan Y.
- Sutrisno Gunawan
- Sylvia den Boer
- Tania Caf
- Tarek Dendane
- Tayfun Adanir
- Tejerina E. E.
- Teresa Mut
- Teresa Sánchez de Dios
- Thille A. W.
- Thomas Bein
- Thomas Lipp
- Thomas Moellhoff
- Thomas Steinke
- Thoralf Kerner
- Tiehe Qin
- Tim Coles
- Tim Houlihan
- Timothy D Girard
- Tom Cowlam
- Tony Sutherland
- Tony Williams
- Travis Parry
- Troy Browne
- Tumbass Volker
- Uli Strauch
- Umesh G
- Unase Büyükkoçak
- V J Cardenas Jr
- Valentín Parra
- Valerio Mangani
- Valery Subbotin
- Valle Pinheiro B.
- Valéria de Carvalho Magela
- Vanesa Ramírez
- Vicente Arraez
- Victoria Goñi
- Vincent John Scott
- Vito Marco Ranieri
- Vivek Joshi
- Wajdi Maazouzi
- Walter Brandt
- Walter Seyde
- Wanxia Li
- Wei He
- Wei Yu
- Wei Zhang
- Weihai Yao
- William Rodriguez-Cintron
- Winfried Schubert
- Wolfgang Baier
- Won-Yeon Lee
- Xi Zhu
- Xianyao Wan
- Xiaobo Huang
- Xue Wang
- Yalin Liu
- Yan Kang
- Yangong Chao
- Yaseen Arabi
- Yi Li
- Yi Yang
- Yogeet Kaur
- Yongjie Yin
- Young Suh G.
- Younsuck Koh
- Yu Bai
- Yuan Xu
- Yuhong Guo
- Yun Seong Kim
- Yunxuan Yue
- Zafer Dogan
- Zalatiel Maycotte Luna
- Zaza Cohen
- Zhengxuan Lv
- Zhenjie Hu
- Zhenyang He
- Zhicheng Zhang
- Zhihua Hu
- Zhixiang Li
- Zoltan Szentkereszty
- Zoraida Parra
- Zsolt Molnar
- Ángela Alonso
- Publication venue
- 'Ovid Technologies (Wolters Kluwer Health)'
- Publication date
- 01/11/2021
- Field of study
OBJECTIVES: To describe the changes in ventilator management over time in patients with neurologic disease at ICU admission and to estimate factors associated with 28-day hospital mortality. DESIGN: Secondary analysis of three prospective, observational, multicenter studies. SETTING: Cohort studies conducted in 2004, 2010, and 2016. PATIENTS: Adult patients who received mechanical ventilation for more than 12 hours. INTERVENTIONS: None. MEASUREMENTS AND MAIN RESULTS: Among the 20,929 patients enrolled, we included 4,152 (20%) mechanically ventilated patients due to different neurologic diseases. Hemorrhagic stroke and brain trauma were the most common pathologies associated with the need for mechanical ventilation. Although volume-cycled ventilation remained the preferred ventilation mode, there was a significant (p < 0.001) increment in the use of pressure support ventilation. The proportion of patients receiving a protective lung ventilation strategy was increased over time: 47% in 2004, 63% in 2010, and 65% in 2016 (p < 0.001), as well as the duration of protective ventilation strategies: 406 days per 1,000 mechanical ventilation days in 2004, 523 days per 1,000 mechanical ventilation days in 2010, and 585 days per 1,000 mechanical ventilation days in 2016 (p < 0.001). There were no differences in the length of stay in the ICU, mortality in the ICU, and mortality in hospital from 2004 to 2016. Independent risk factors for 28-day mortality were age greater than 75 years, Simplified Acute Physiology Score II greater than 50, the occurrence of organ dysfunction within first 48 hours after brain injury, and specific neurologic diseases such as hemorrhagic stroke, ischemic stroke, and brain trauma. CONCLUSIONS: More lung-protective ventilatory strategies have been implemented over years in neurologic patients with no effect on pulmonary complications or on survival. We found several prognostic factors on mortality such as advanced age, the severity of the disease, organ dysfunctions, and the etiology of neurologic disease