16 research outputs found

    Intercellular adhesion molecule 1 (ICAM-1) a novel co-receptor for c-Met

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    АНЕСТЕЗИЯ У БОЛЬНЫХ С ХИРУРГИЧЕСКОЙ ИНФЕКЦИЕЙ. ВЫБОР МЕТОДА

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    Possibilities of application of various methods of anesthesia of patients with surgical infections are reviewed in the article. The problems of anesthesia related with peculiarities of the process of surgical infection, localization, and characteristics of surgical treatment, as well as with the initial physical status of the patient determined with the age and severity of accompanying diseases were discussed. В статье рассмотрены возможности проведения различных методов анестезии у больных с хирургической инфекцией. Обсуждены проблемы анестезии, связанные с особенностями течения хирургической инфекции, локализацией и особенностями оперативного лечения, а также с исходным физическим статусом пациента, определяемым возрастом и тяжестью сопутствующих заболеваний.

    c-Met recruits ICAM-1 as a coreceptor to compensate for the loss of CD44 in Cd44 null mice

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    CD44v6 acts as a coreceptor for the receptor tyrosine kinases c-Met and VEGFR-2. It is shown that ICAM-1 can act as a new coreceptor in CD44v6-negative tumor cells. Furthermore, ICAM-1 can substitute for CD44v6 as a coreceptor for c-Met in primary hepatocytes and in liver regeneration in Cd44 null mice
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