Three-dimensional light bullets in a Bragg medium with carbon nanotubes

We present a theoretical study of the propagation of three-dimensional extremely short electromagnetic pulses (a.k.a. light bullets) through a Bragg medium containing an immersed array of carbon nanotubes. We demonstrate the possible stable propagation of such light bullets. In particular, our results suggest these light bullets can carry information about the Bragg medium itself.Comment: To appear in Appl. Phys.

Impact and intracellular localization of antibodies to DNA in MDCK cells

A study was performed with liquid chromatography of highly purified antibodies to DNA of IgG from blood serum of healthy donors-SLE or RA patients and their clinically healthy relatives. It was shown that, depending on the pathology, these antibodies were distinguished by DNA-hydrolyzing activity. These antibodies were incubated with MDCK cells. It was found that they were mostly localized in the vicinity of the nucleus and affected the cellular morphology, number of viable cells, and chromatin of MDCK cells differently. The biological role of antibodies to DNA is discussed. © 2013 Pleiades Publishing, Ltd

Influence of serum antibodies to DNA on the Madin-Darby canine kidney epithelial cells in vitro in depend of immunoreactive regions of the IgG molecule

The data obtained on cell lines MDCK showed that for implementation of the biological function of antibodies to DNA both normal and pathological need the participation as Fab- and Fc-fragments of molecules of IgG. However, antigen-binding region is responsible for the manifestation of the biological function of SLE antibodies to DNA more immunoreactive than antibodies in normal and constant region is probably responsible for the active conformation of antibody for pathobiological function of antibodies to DNA in the cell

Comparison of operation of physical and simulation model of proportional distributor

In almost all industries, belt conveyors are used, which ensure the continuity of the processes of transporting various types of goods and materials. Their use allows to deliver piece loads and materials that have a bulk / lump structure to the desired objec

Comparison of operation of physical and simulation model of proportional distributor

In almost all industries, belt conveyors are used, which ensure the continuity of the processes of transporting various types of goods and materials. Their use allows to deliver piece loads and materials that have a bulk / lump structure to the desired objec

The role of Advocacy Coalitions in Shaping the Technological Innovation Systems: The Case of the Russian Renewable Energy Policy

Many hydrocarbon‐rich countries have recognized the global shift towards renewable energy sources, and Russia is not an exception. Drawing on two strands of literature—technological innovation systems and the advocacy coalition framework—we investigate the roles of actors and coalitions in shaping the Russian renewable energy policy and explore why particular renewable energy sources have progressed more than others, and what the main reasons are for their sudden development. The results show that the more successful renewable energy industries are those that were promoted by influential actors from traditional energy industries. Moreover, these actors also promoted the specific design of support schemes for renewable energy policy in Russia. We discuss the importance of policy process theories for understanding energy transition studies and provide specific policy recommendations for policy creation in the renewables industry. © 2021 by the authors. Licensee MDPI, Basel, Switzerland

Molecular characterization and susceptibility of methicillin-resistant and methicillin-susceptible Staphylococcus aureus isolates from hospitals and the community in Vladivostok, Russia

AbstractA prospective study was conducted during an 8-month period, from August 2006 to April 2007, to describe the epidemiology of Staphylococcus aureus-associated infections. In addition, the molecular characteristics, antimicrobial susceptibilities and antibiotic resistance determinants were identified in S. aureus isolates from hospitals and the community in Vladivostok, Russia. Among the 63 S. aureus isolates eligible for this study, methicillin resistance was observed in 48% (n = 30). Hospital-acquired strains accounted for 93% (28/30) of all methicillin-resistant S. aureus (MRSA) isolates. The major MRSA clone (sequence type (ST) 239, staphylococcal cassette chromosome mec (SCCmec) type III, Panton--Valentine leukocidin (PVL)-negative, with two related staphylococcal protein A gene (spa) types (types 3 and 351)) represented 90% of all of the MRSA isolates. This clone was multidrug-resistant, and 41% of isolates showed resistance to rifampicin. Community-acquired MRSA isolates (n = 2) were categorized as ST30, SCCmecIV, spa type 19, and PVL--positive, and as ST8, SCCmecIV, of a novel spa type 826, and PVL-negative. Eight different STs were detected among methicillin-susceptible S. aureus (MSSA) isolates, of which 55% were PVL--positive. One MSSA clone, which was categorized as ST121, spa type 273, and PVL--positive, caused fatal community-acquired pneumonia infections. The strains predominantly isolated in hospitals in Russia belonged to the multidrug-resistant Brazilian/Hungarian ST239 MRSA clone; however, this clone has new antibiotic susceptibilities. Additionally, the emergence of PVL--positive MSSA strains with enhanced virulence was observed, warranting continued surveillance

Special features of the DNA-hydrolyzing activity of the antibodies in systemic lupus erythematosus

Two types of IgG anti-DNA antibodies exhibiting DNA-hydrolyzing activity have been isolated from blood serum of patients with systemic lupus erythematosus. This DNase activity of antibodies differs from serum DNases by the non-processive mode, temperature resistance, pH optimum, and the rate of DNA hydrolysis. It is suggested that the anti-DNA antibody molecule possessing DNase activity contains two sites: one site determines specificity of antibody-DNA interaction, whereas the other is responsible for manifestation of the catalytic activity

Optimizing DNA visualization with a solver P47H atomic-force microscope

The conditions for visualizing DNA molecules with a Solver P47H atomic-force microscope (NT-MTD, Moscow, Russia) were optimized. The DNA samples had different sizes, types, and conformations (pBR-322 plasmid DNA and chicken erythrocyte DNA) and were immobilized on mica. The microscope was equipped with a Smena-B detecting head and was operated in a tapping mode. The dependence of the amplitude of tip oscillations on the spacing between the tip and the test sample's surface was used to determine the optimum parameters of scanning. The highest quality and reproducibility of the DNA images were attained by scanning with a small initial amplitude (9-23 nm) of cantilever oscillations and an optimum gain (0.08-0.3). Images with the highest contrast were obtained in the amplitude curve's region corresponding to a repulsive interaction regime. The operating amplitude was set at one-half (or slightly less than) the initial amplitude of tip oscillations. © 2005 Pleiades Publishing, Inc