Destructive energy impact to the myocard damage: between technological advantages and risk

Background: The aim of the study was to evaluate and compare destruction effect to different heart structures using RF, cryo and laser methodology in animal (pig) model. Methods: Ablation procedure was performed on right and left pulmonary veins area, free wall of right and left atrias, and free wall of ventricles positioning ablation electrode from endocardial side. Ablation electrodes were inserted through an incision in right/left auricle. The effects of ablation were observed visually and using thermography for temperature control. Results: Standard recommended parameters for both of used destruction energies were possible to evoke quick critical scar formation and rupture. Temperature in cardiac surface differs from 34.5 till 70.2 °C, and directly depends from electrode compression level, time of application and energy power. We express dissent from the general view, what destruction in cardiac structures is point like. We observed enough high range of temperature dispersion, especially in ventricles. Conclusions: Usage of thermography enable to estimate peculiarities and borders of destruction site, optimize parameters of ablation, allows us to avoid or minimize undesirable effects, save structures and improve clinical outcomes

Conditions for Existence of Uniformly Consistent Classifiers

We consider the statistical problem of binary classification, which means attaching a random observation X from a separable metric space E to one of the two classes, 0 or 1. We prove that the consistent estimation of conditional probability p(X)= P(Y=1 X) , where Y is the true class of X, is equivalent to the consistency of a class of empirical classifiers. We then investigate for what classes P there exist an estimate p that is consistent uniformly in p P. We show that this holds if and only if P is a totally bounded subset of L1(Eμ), where μ is the distribution of X. In the case, where E is countable, we give a complete characterization of classes π, allowing consistent estimation of p, uniform in (μ,p)ϵπ