Background: The aim of the study was to evaluate and compare destruction effect to different heart structures using RF, cryo and laser methodology in animal (pig) model. Methods: Ablation procedure was performed on right and left pulmonary veins area, free wall of right and left atrias, and free wall of ventricles positioning ablation electrode from endocardial side. Ablation electrodes were inserted through an incision in right/left auricle. The effects of ablation were observed visually and using thermography for temperature control. Results: Standard recommended parameters for both of used destruction energies were possible to evoke quick critical scar formation and rupture. Temperature in cardiac surface differs from 34.5 till 70.2 °C, and directly depends from electrode compression level, time of application and energy power. We express dissent from the general view, what destruction in cardiac structures is point like. We observed enough high range of temperature dispersion, especially in ventricles. Conclusions: Usage of thermography enable to estimate peculiarities and borders of destruction site, optimize parameters of ablation, allows us to avoid or minimize undesirable effects, save structures and improve clinical outcomes