Thrombelastografische untersuchungen bei patienten mit veranderungen des Koagulum

Koristeći trombelastografska ispitivanja, trebalo je dokazati, koji su opšti i lokalni činioci mogli uticati na propadanje koaguluma u rani posle vađenja zuba. Ova ispitivanja su vršena u 13 pacijenata, u kojih su komplikacije nastale u smislu produženog krvavljenja (pet) i alveolita (osam). Rezultati trombelastografskih merenja pokazuju, da su promene nastale u rani, posle vađenja zuba, posledica dejstva lokalnih činilaca (trauma, pljuvačka, infekcija), a ne promena u opštem sistemu koagulacije i fibrinolize (humoralnom sistemu). Trombelastogrami pokazuju, u devet slučajeva, hiperkoagulabilnu reakciju krvi, a u četiri slučaja, normokoagulabiinost. Moglo bi se, čak, pretpostaviti, da su u slučajevima hiperkoagulabilnosti i reakcije fibrinolize bile ubrzane.The thrombelastographic investigation was applied to find out which general and focal factors could influence the destruction of coagulum in the wound caused by a tooth extraction. The investigation was carried out in 13 patients, including five cases with prolongated bleeding and eight cases with alveolations. The results of the trombelastographic measurements show that the changes in the wound caused by a tooth extraction are due to the effect of local factors (trauma, saliva and infection) and not to the general system of coagulation and fibrinolysis (humoral system). Thrombelastograms show hypercoagulable blood reaction in nine cases and normal coagulability in four cases. It might be assumed that in cases with hypercoagulability the fibrinolysis reactions were also accelerated.Thromboelastografische Untersuchungen sollten nachweisen welche allgemeine und lokale Faktoren auf den Schwund des Koagulums nach Zahnextraktion Einfluss haben. Diese Untersuchungen wurden an 13 Patienten ausgeführt, darunter bei fünf mit verlängerter Blutgerinnungszeit, während bei acht entzündliche Komplikationen der Alveole zu verzeichnen waren. Die Resultate der thromboelastografischen Messungen weisen darauf hin, dass die Veränderungen in der Wunde nach Zahnextraktion die Folge von lokalen Faktoren, und zwar Trauma, Speichel, Infektion, sind und nicht auf Veränderungen im allgemeinen System der Koagulation und der Fibrinolyse, zuruckzuführen sind. Tromboelastogarmme zeigten in neun Fällen eine hyperkoagulabile Blutreaktion, bloss in vier Fällen eine Normokoagulabilität. Man könte sogar voraussetzen, dass sogar bei Hyperkoagulabilität die Reaktion der Fibrinolyse beschleunigt war

Predictors of Aggressive Behaviour in Children with Autism Spectrum Disorder

Introduction: Aggressive behaviour is not the main symptom of autism spectrum disorders, and if it occurs in this population, it is a consequence of some other factors. Objectives: With regard to that, the aim of this paper is to determine to what extent certain aspects of executive functions, severity of autism, sleep habits, and parenting actions contribute to the manifestation of different forms of aggressive behaviour in children with an autism spectrum disorder. Methods: The sample included 40 children with autism spectrum disorders, 5-7 years of age (M=6.18, SD= .55). The following instruments were used in the assessment: The Children’s Scale of Hostility and Aggression – Reactive/Proactive, Gilliam Autism Rating Scale – Third Edition, The Children’s Sleep Habits Questionnaire and Behavior Rating Inventory of Executive Function. Results: The obtained results showed that sleep problems were the most significant predictor of verbal, physical and covert aggression. From the domain of behavioural aspects of executive functions, only task monitor was a significant predictor of bullying, and inhibit and shift were significant predictors of hostility. From the field of autistic disorders, significant predictors of aggressive behaviour were emotional responses (as predictors of bullying, covert aggression and hostility), and maladaptive speech (as a predictor of verbal aggression, covert aggression and hostility). Punitive discipline was a significant factor only in explaining verbal aggression. Conclusion: Practical implications of this research indicate that, in treating aggressive behaviour in children with ASD, more attention should be paid to sleep habits, practising task monitor, inhibit and shift skills, and avoiding rigorous punitive measures

A New Aculodes Species (Prostigmata: Eriophyidae) Described from an Invasive Weed by Morphological, Morphometric and DNA Barcode Analyses †

A new species of eriophyoid mite, Aculodes marcelli sp. nov., was discovered on cheatgrass, Anisantha tectorum (L.) Nevski (syn. Bromus tectorum L.), an annual grass that is native to Eurasia and Northern Africa. This grass was introduced to North America near the end of the 19th century and now is widespread and associated with the observed increases in the size, frequency, and intensity of wildfires in western N. America. In this paper, A. marcelli sp. nov., is morphologically described and illustrated. Compared with other Aculodes spp., it differs based on morphology and the sequence of the mitochondrial cytochrome oxidase gene, subunit I (MT-CO1). Results of morphometric analysis showed clear differentiation between A. marcelli sp. nov., and the most similar congener, A. altamurgiensis from Taeniatherum caput-medusae. Analysis of MT-CO1 sequence divergence revealed significant levels of genetic variation (17.7%) and supported the results from the morphometric analysis; therefore, it is determined that they are two different species. Aculodes marcelli sp. nov., is a new candidate agent for classical biological control of A. tectorum. © 2022 by the authors

The possibility of GIS application for the needs of planning transport of hazardous waste

Hazardous waste management system as a separate segment includes the transportation of hazardous waste, which specifically includes transportation from the place of its origin to the place of storage, treatment or final disposal. This function includes all forms of transport, but experience has shown that the most used one is a road traffic, which also carries an extremely high risk of possible occurrence of accident and endangering the local community, material resources and environment. Therefore, it is necessary to establish control over transport option, and the risk too, which is achieved by conducting risk assessments and then selecting the optimal transport routes. In each of these phases GIS has found its major application, enabling operation with different types of data, a simplified procedure of multi-criteria analysis and a clear visual representation of the received results.

Exploring the phylogenetic signal in the cranial variation of European populations of grayling (Actinopterygii, Salmonidae)

This is a preliminary and exploratory study of cranial variation in European populations of grayling. We investigated the correspondence between size/shape variation of the dorsal (DC), ventral (VC) and occipital (OC) cranium and phylogenetic relationships (inferred from mitochondrial control region – mtDNA CR and microsatellite DNA data) of six grayling populations: three from Balkan phylogenetic clade and two from Caspian phylogenetic clade of the European grayling Thymallus thymallus and one population of the Adriatic grayling Thymallus aeliani, which until recently was considered the Adriatic phylogenetic clade of T. thymallus. Significant size and shape differences were found between populations in all three cranial views. However, significant size-related shape variation (allometry) was found for DC and VC, but not for OC. The size variation of each cranial view does not contain phylogenetic signal, but size variation of OC is consistent with genetic variation inferred from microsatellite DNA. Regarding shape variation, a significant phylogenetic signal was detected only for OC, and only the shape variation of OC is consistent with the genetic variation inferred from the mtDNA CR. Moreover, the Adriatic grayling T. aeliani (Soča population) was clearly separated from the three T. thymallus populations of the Balkan phylogenetic clade and the two T. thymallus populations of the Caspian phylogenetic clade only at the level of OC. Thus, our results suggest that different cranial regions differ in allometry, reflect phylo(genetic) relationships differently, and exhibit differences in ecophenotypic plasticity, with OC seeming best suited to represent the phylogenetic relationships of the grayling populations studied

CARD15 gene polyrnorphisms in Serbian patients with Crohn's disease: genotype-phenotype analysis

Objective Genetic heterogeneity and incomplete phenotype penetrance complicate genetic analysis of Crohn's disease (M. Studies in western Europe have shown that CARD15 polymorphisms increase susceptibility to CD, but frequencies vary within different European populations. The aim here was to evaluate the prevalence of CARD15 mutations and their phenotypic correlation in a Serbian population. Materials and methods 131 patients with CD, 65 patients with ulcerative colitis, and 88 healthy controls were genotyped for three common mutations (R702W, G908R, Leu1007insC) by PCR-restriction fragment length polymorphism. chi(2) and Student's t-test were used for statistical assessment. Results At least one CARD15 disease-associated allele was found in 35.11 % patients with CD, 14.77% of healthy controls (P=0.001), and 7.69% patients with ulcerative colitis (P= 0.0001). The L1007fs mutation showed a significant association with CD (P lt 0.0001). The frequency of R702W mutant allele was almost equal in the control group and CD patients Univariate analyses established that CARD15 carriers had a significantly higher risk of isolated ileal location [P=0.042; odds ratio (OR) 2.30; 95% confidence interval (CI): 1.02-5.191, fibrostenotic behavior (P lt 0.0001; OR 9.86; 95% CI: 4.29-22.62), surgical resection (P=0.036; OR 2.2; CI, 1.046-4.626), and earlier onset of disease (P=0.026). Conclusion This study confirms that CARD15 carriers, especially L1007fs mutants, in central Europeans have an increased risk of CD and it is associated with earlier onset, ileal, fibrostenotic disease and a higher risk of surgery. Any influence of latitude is not matched by an east-west divide on the genotype frequency and phenotype of CD within Europe