5 research outputs found
Adapting standard maintenance approaches for mining excavators to actual operating condition
Significant portion of the annual calendar fund-time work of mining excavators spent on maintaining its working condition by carrying out preventive and repair regulatory activities and recovery in the event of emergency failures and maintenance and repair expenses constitute a significant proportion of the cost of excavation of mining rock. To assess the effectiveness of machinery a non-standard indicator, the coefficient of technical readiness, applied which does not have a single assessment methodology. At the present stage of machinery development, existing quarry dispatching systems allow you to allocate any of its elements from the fund-time of mining excavators: productive time, time spent in repair and maintenance and also classify other time costs of a particular machine which allowed an appropriate analysis. Analysis showed that at the current organization of MaR (maintenance and repair) there is significant potential to reduce repair impacts, as well as to ensure a reduction in the cost of routine maintenance, to remove maintenance and repair measures from the category of costly ones, at least for self-sufficiency without compromising the quality of these works and the reliability of the excavator as a whole. Β© Published under licence by IOP Publishing Ltd
Device for integrated diagnostics of mining machines triboelements
This article presents the results of multiple-conditions wear-resistance tests for the antifriction bearings that are used in a milling tool. The test was performed on a one-fifth milling tool model. The tests were divided into three stages. The first testing stage included tests of a model with a new undamaged bearing. The second stage included tests of a model with a bearing that is worn out by approximately 50%. The third stage included tests of a model with a completely worn out antifriction bearing. Along with vibroacoustic tests, we measured the temperatures of the tested triboelement. In this article, we provide amplitude-frequency values of vibroacoustic signals recorded during the tests of a model with an undamaged antifriction bearing, a bearing with 50% worn-out extent, and 100% worn-out bearing. Appropriate resistance levels of complex machine elements cannot be achieved without systems of triboelements condition control. We suggest attaching temperature and vibroacoustic sensors to the critical elements of a peat winning machine that provide data for integral analysis of triboelemets condition and prevent failures when damage is recorded. Integral analysis of the technical condition of the main triboelements will allow performing the highly precise prognosis of the remaining life of a peat-winning machine, thus preventing failures in peat mining seasons
Column chromatography USED in purification of genotoxic impurity sample of imatinib mesylate substance
The article describes a simple method for purifying N-(5-amino-2-methylphenyl)-4-(3-pyridyl)-2-pyrimidineamine for further use as a standard for quantitative determination of genotoxic impurities substance imatinib mesylate. Experimentally proved choice of sorbent used for purification of N-(5-amino-2-methylphenyl)-4-(3-pyridyl)-2-pyrimidineamine. The advantage of column chromatography on neutral alumina prior to crystallization methods presented in the literature. Comparative chromatographic and spectral characteristics of N-(5-amino-2-methylphenyl)-4-(3-pyridyl)-2-pyrimidineamine before and after purification. NMR spectroscopy evaluated quantitative content of the target substance in the purified sample
ΠΠΎΠ»ΠΎΠ½ΠΎΡΠ½Π°Ρ Ρ ΡΠΎΠΌΠ°ΡΠΎΠ³ΡΠ°ΡΠΈΡ Π² ΠΎΡΠΈΡΡΠΊΠ΅ ΠΎΠ±ΡΠ°Π·ΡΠ° Π³Π΅Π½ΠΎΡΠΎΠΊΡΠΈΡΠ½ΠΎΠΉ ΠΏΡΠΈΠΌΠ΅ΡΠΈ ΡΡΠ±ΡΡΠ°Π½ΡΠΈΠΈ ΠΈΠΌΠ°ΡΠΈΠ½ΠΈΠ±Π° ΠΌΠ΅Π·ΠΈΠ»Π°Ρ
The article describes a simple method for purifying N-(5-amino-2-methylphenyl)-4-(3-pyridyl)-2-pyrimidineamine for further use as a standard for quantitative determination of genotoxic impurities substance imatinib mesylate. Experimentally proved choice of sorbent used for purification of N-(5-amino-2-methylphenyl)-4-(3-pyridyl)-2-pyrimidineamine. The advantage of column chromatography on neutral alumina prior to crystallization methods presented in the literature. Comparative chromatographic and spectral characteristics of N-(5-amino-2-methylphenyl)-4-(3-pyridyl)-2-pyrimidineamine before and after purification. NMR spectroscopy evaluated quantitative content of the target substance in the purified sample.Π ΡΡΠ°ΡΡΠ΅ ΠΏΠΎΠΊΠ°Π·Π°Π½ ΠΏΡΠΎΡΡΠΎΠΉ ΡΠΏΠΎΡΠΎΠ± ΠΎΡΠΈΡΡΠΊΠΈ N-(5-Π°ΠΌΠΈΠ½ΠΎ-2-ΠΌΠ΅ΡΠΈΠ»ΡΠ΅Π½ΠΈΠ»)-4-(3-ΠΏΠΈΡΠΈΠ΄ΠΈΠ»)-2-ΠΏΠΈΡΠΈΠΌΠΈΠ΄ΠΈΠ½Π°ΠΌΠΈΠ½Π° Π΄Π»Ρ Π΄Π°Π»ΡΠ½Π΅ΠΉΡΠ΅Π³ΠΎ ΠΈΡΠΏΠΎΠ»ΡΠ·ΠΎΠ²Π°Π½ΠΈΡ Π΅Π³ΠΎ Π² ΠΊΠ°ΡΠ΅ΡΡΠ²Π΅ ΡΡΠ°Π½Π΄Π°ΡΡΠ° ΠΏΡΠΈ ΠΊΠΎΠ»ΠΈΡΠ΅ΡΡΠ²Π΅Π½Π½ΠΎΠΌ ΠΎΠΏΡΠ΅Π΄Π΅Π»Π΅Π½ΠΈΠΈ Π³Π΅Π½ΠΎΡΠΎΠΊΡΠΈΡΠ½ΠΎΠΉ ΠΏΡΠΈΠΌΠ΅ΡΠΈ ΡΡΠ±ΡΡΠ°Π½ΡΠΈΠΈ ΠΈΠΌΠ°ΡΠΈΠ½ΠΈΠ±Π° ΠΌΠ΅Π·ΠΈΠ»Π°Ρ. ΠΠΊΡΠΏΠ΅ΡΠΈΠΌΠ΅Π½ΡΠ°Π»ΡΠ½ΠΎ ΠΎΠ±ΠΎΡΠ½ΠΎΠ²Π°Π½ Π²ΡΠ±ΠΎΡ ΡΠΎΡΠ±Π΅Π½ΡΠ°, ΠΏΡΠΈΠΌΠ΅Π½ΡΠ΅ΠΌΠΎΠ³ΠΎ Π΄Π»Ρ ΠΎΡΠΈΡΡΠΊΠΈ N-(5-Π°ΠΌΠΈΠ½ΠΎ-2-ΠΌΠ΅ΡΠΈΠ»ΡΠ΅Π½ΠΈΠ»)-4-(3-ΠΏΠΈΡΠΈΠ΄ΠΈΠ»)-2-ΠΏΠΈΡΠΈΠΌΠΈΠ΄ΠΈΠ½Π°ΠΌΠΈΠ½Π°. ΠΠΎΠΊΠ°Π·Π°Π½ΠΎ ΠΏΡΠ΅ΠΈΠΌΡΡΠ΅ΡΡΠ²ΠΎ ΠΊΠΎΠ»ΠΎΠ½ΠΎΡΠ½ΠΎΠΉ Ρ
ΡΠΎΠΌΠ°ΡΠΎΠ³ΡΠ°ΡΠΈΠΈ Π½Π° Π½Π΅ΠΉΡΡΠ°Π»ΡΠ½ΠΎΠΌ ΠΎΠΊΡΠΈΠ΄Π΅ Π°Π»ΡΠΌΠΈΠ½ΠΈΡ ΠΏΠ΅ΡΠ΅Π΄ ΠΊΡΠΈΡΡΠ°Π»Π»ΠΈΠ·Π°ΡΠΈΠΎΠ½Π½ΡΠΌΠΈ ΠΌΠ΅ΡΠΎΠ΄Π°ΠΌΠΈ, ΠΏΡΠ΅Π΄ΡΡΠ°Π²Π»Π΅Π½Π½ΡΠΌΠΈ Π² Π»ΠΈΡΠ΅ΡΠ°ΡΡΡΠ½ΡΡ
ΠΈΡΡΠΎΡΠ½ΠΈΠΊΠ°Ρ
. ΠΡΠΈΠ²Π΅Π΄Π΅Π½Ρ ΡΡΠ°Π²Π½ΠΈΡΠ΅Π»ΡΠ½ΡΠ΅ Ρ
ΡΠΎΠΌΠ°ΡΠΎΠ³ΡΠ°ΡΠΈΡΠ΅ΡΠΊΠΈΠ΅ ΠΈ ΡΠΏΠ΅ΠΊΡΡΠ°Π»ΡΠ½ΡΠ΅ Ρ
Π°ΡΠ°ΠΊΡΠ΅ΡΠΈΡΡΠΈΠΊΠΈ N-(5-Π°ΠΌΠΈΠ½ΠΎ-2-ΠΌΠ΅ΡΠΈΠ»ΡΠ΅Π½ΠΈΠ»)-4-(3-ΠΏΠΈΡΠΈΠ΄ΠΈΠ»)-2-ΠΏΠΈΡΠΈΠΌΠΈΠ΄ΠΈΠ½Π°ΠΌΠΈΠ½Π° Π΄ΠΎ ΠΈ ΠΏΠΎΡΠ»Π΅ ΠΎΡΠΈΡΡΠΊΠΈ. ΠΠ΅ΡΠΎΠ΄ΠΎΠΌ Π―ΠΠ ΡΠΏΠ΅ΠΊΡΡΠΎΡΠΊΠΎΠΏΠΈΠΈ ΠΏΡΠΎΠ²Π΅Π΄Π΅Π½Π° ΠΎΡΠ΅Π½ΠΊΠ° ΠΊΠΎΠ»ΠΈΡΠ΅ΡΡΠ²Π΅Π½Π½ΠΎΠ³ΠΎ ΡΠΎΠ΄Π΅ΡΠΆΠ°Π½ΠΈΡ ΡΠ΅Π»Π΅Π²ΠΎΠ³ΠΎ Π²Π΅ΡΠ΅ΡΡΠ²Π° Π² ΠΎΡΠΈΡΠ΅Π½Π½ΠΎΠΌ ΠΎΠ±ΡΠ°Π·ΡΠ΅