12 research outputs found
Prolonging hormone sensitivity in prostate cancer xenografts through dual inhibition of AR and mTOR
- Author
- A Boulay
- A M H Brodie
- A Schayowitz
- A Schayowitz
- B Cinar
- C Festuccia
- CD Chen
- CW Gregory
- CW Gregory
- EA Mostaghel
- FK Habib
- G Sabnis
- GC Buckle
- GN Thalmann
- GN Thalmann
- HK Lin
- HK Lin
- J Edwards
- J Edwards
- J Edwards
- J Heracek
- J Lin
- JL Mohler
- JS Horoszewicz
- L Yang
- M Kaarbø
- M Manin
- M Sun
- MA Titus
- MJ Linja
- O Goloubeva
- P Koivisto
- PM Ghosh
- S Baron
- S Vignot
- T Vasaitis
- T Visakorpi
- V C O Njar
- VD Handratta
- Z Culig
- Z Culig
- Publication venue
- Nature Publishing Group
- Publication date
- Field of study
Get PDFImproved Procedure for Preparation of Abiraterone Acetate
- Author
- Publication venue
- 'American Chemical Society (ACS)'
- Publication date
- Field of study
No full textDiscovery and Development of Galeterone (TOK-001 or VN/124-1) for the Treatment of All Stages of Prostate Cancer
- Author
- Anderson J.
- Angela M. H. Brodie
- Brodie A. M.
- Brodie A. M.
- Bruno R. D.
- Bruno R. D.
- Chumsri S.
- Clegg N. J.
- Clement O. O.
- Dreicer J. R.
- Grigoryev D. N.
- Grigoryev D. N.
- Grigoryev D. N.
- Handratta V. D.
- Handratta V. D.
- Kaku T.
- Kim W.
- Li J.
- Logothetis C. J.
- Mahler C.
- Montgomery G.
- Nicolaou K.
- Njar V. C.
- Njar V. C.
- Njar V. C.
- Njar V. C.
- Nnane I. P.
- Nnane I. P.
- Nnane I. P.
- Pereira de Jesus-Tran K.
- Purushottamachar P.
- Rehman Y.
- Ryan C. J.
- Schayowitz A.
- Schayowitz A.
- Schneider R.
- Semenas J.
- Siegel R.
- Vasaitis T.
- Vasaitis T.
- Vasaitis T. S.
- Vincent C. O. Njar
- Yin L.
- Yuan X.
- Publication venue
- 'American Chemical Society (ACS)'
- Publication date
- Field of study
No full textSynthesis of novel 1,2,3-triazolyl derivatives of pregnane, androstane and d
- Author
- Agalave
- Aher
- Akhrem
- Akhtar
- Auchus
- Banday
- Banday
- Baston
- Bischofberger
- Bori
- Brunner
- Brunner
- Bruno
- Bryce
- Burkhart
- Cabeza
- Chan
- Creger
- Czakó
- Fehér
- Ferro
- Franc
- Frank
- Fukushima
- Gasi
- Gennadij V. Latyshev
- Girdhar
- Gogoi
- Grigoryev
- Guzman
- Haidar
- Haidar
- Haider
- Handratta
- Hartmann
- Hartmann
- Hein
- Hein
- Hernandez
- Irina P. Beletskaya
- Jindal
- Kirk
- Kirk
- Kirk
- Kiss
- Komeno
- Kotora
- Kotovshchikov
- Kovács
- Kádár
- Kádár
- Kádár
- Latyshev
- Liang
- Ling
- Logothetis
- Lukashev
- Meldal
- Molina
- Moreira
- Moreira
- Moses
- Nikolay V. Lukashev
- Njar
- O'Donnell
- Ohshima
- Paquette
- Pore
- Potter
- Pérez-Labrada
- Rehman
- Rodionov
- Russell
- Salvador
- Schwarz
- Shao
- Shao
- Shi
- Shi
- Skoda-Földes
- Sokolova
- Struthers
- Stulov
- Taub
- Turner
- Vasaitis
- Vasaitis
- Vasaitis
- Vasilevsky
- Vatmurge
- Vatmurge
- Wang
- Wang
- Wendler
- Wölfling
- Yousuf
- Yury N. Kotovshchikov
- Publication venue
- 'Royal Society of Chemistry (RSC)'
- Publication date
- 01/01/2014
- Field of study
No full textReplacement of Imidazolyl by Pyridyl in Biphenylmethylenes Results in Selective CYP17 and Dual CYP17/CYP11B1 Inhibitors for the Treatment of Prostate Cancer
- Author
- Andrea C.
- Attard G.
- Baston E.
- Chan F. C. Y.
- Chung B. C.
- Denner K.
- Ehmer P. B.
- Ehmer P. B.
- Eigen M.
- Eklund J.
- Geller J.
- Gobbi S.
- Handratta V. D.
- Hara T.
- Hartmann R. W.
- Hartmann R. W.
- Hartmann R. W.
- Hill R. A.
- Hille U. E.
- Hille U. E.
- Hu Q.
- Hu Q.
- Hu Q.
- Huhtaniemi I.
- Hussein W. I.
- Hutschenreuter T. U.
- Jagusch C.
- Kataoka K.
- Labrie F.
- Lamberts S. W. J.
- Le Borgne M.
- Leonetti F.
- Leroux F.
- Lucas S.
- Lucas S.
- Marco R.
- Njar V. C. O.
- Palmgren J. S.
- Picard F.
- Potter G. A.
- Rajec J.
- Reed A. B.
- Richard M.
- Richard M.
- Temple T. E.
- Ulmschneider S.
- Ulmschneider S.
- Vandenput L.
- Wachall B. G.
- White P. C.
- Wächter G. A.
- Zhao X. Y.
- Publication venue
- 'American Chemical Society (ACS)'
- Publication date
- Field of study
No full textClassification of Cytochrome P450 Inhibitors with Respect to Binding Free Energy and pIC 50
- Author
- Arimoto R.
- Armutlu P.
- Asano T.
- Asikainen A. H.
- Auchus R. J.
- Balaban A. T.
- Chohan K. K.
- Chun Y. J.
- Cohen L. H.
- Dong L. H.
- EL-Manzalawy Y. H. V.
- Fischer V.
- Fonnepfister R.
- Friedman J.
- Friedman N.
- Grimm S. W.
- Hall M.
- Handratta V. D.
- Hu Q. Z.
- Hutzler J. M.
- Jones B. C.
- Jorgensen W. L.
- Kahraman P.
- Kemp C. A.
- Kier L. B.
- Kier L. B.
- Kitchen D. B.
- Kontijevskis A.
- Korhonen L. E.
- Kubinyi H.
- Liu Y.
- Lutz M.
- Lynch T.
- MacKerell A. D.
- Marechal J. D.
- McKillop D.
- Moody G. C.
- Moon T.
- Morris G. M.
- Nakamura T.
- Nicolas J. M.
- Nnane I. P.
- Nnane I. P.
- Obach R. S.
- Obach R. S.
- Pelkonen O.
- Phillips J. C.
- Prakash C.
- Rahnasto M.
- Riley R. J.
- Robertson G. R.
- Sai Y.
- Schwede T.
- Shader R. I.
- Taavitsainen P.
- Todeschini R.
- Turpeinen M.
- Uney F.
- Vaz R. J.
- Venhorst J.
- Vickers A. E. M.
- von Moltke L. L.
- Walker D. K.
- Walsky R. L.
- Whitley D. C.
- Wiener H.
- Wold S.
- Yao X. J.
- Yap C. W.
- Yu J. L.
- Publication venue
- 'American Chemical Society (ACS)'
- Publication date
- Field of study
No full textSystematic Structure Modifications of Multitarget Prostate Cancer Drug Candidate Galeterone To Produce Novel Androgen Receptor Down-Regulating Agents as an Approach to Treatment of Advanced Prostate Cancer
- Author
- Abhijit M. Godbole
- Andrew K. Kwegyir-Afful
- Attard G.
- Balasubramanian S.
- Berges R. R.
- Bissantz C.
- Bradbury R. H.
- Brandt G. E.
- Brik A.
- Bruno R. D.
- Bryce A.
- Calogeropoulou T.
- Cao B.
- Chassaing C.
- Chaudhaery S. S.
- Chen C. D.
- Chen Y.
- Cheng H.
- Clegg N. J.
- Davenport A. P.
- Dehm S. M.
- Devlin T. A.
- DeVore N. M.
- Fan M.
- Geary T. G.
- Godbole A. M.
- Godbole A. M.
- Godbole A. M. N.
- Guo Z.
- Guo Z.
- Haile S.
- Handratta V. D.
- Hanson R. N.
- Holland H. L.
- Hu R.
- Hu R.
- Jung M. E.
- Kaku T.
- Lalji K. Gediya
- Li J.
- Li X.
- Liu W.
- Marlena S. Martin
- Mashima T.
- Montgomery R. B.
- Moreira V. M.
- Mostaghel E. A.
- Mostaghel E. A.
- Mukherji D.
- Njar V. C.
- Njar V. C.
- Paller C. J.
- Pereira de Jesus-Tran K.
- Pereira de Jesus-Tran K.
- Pike A. C.
- Potter G. A.
- Puranik Purushottamachar
- Purushottamachar P.
- Purushottamachar P.
- Qian K.
- Reid A. H.
- Roy J.
- Sadar M. D.
- Schayowitz A.
- Schayowitz A.
- Senthilmurugan Ramalingam
- Snoek R.
- Soifer H. S.
- Stanbrough M.
- Sun S.
- Tadas S. Vasaitis
- Tran C.
- Vacondio F.
- Vasaitis T.
- Vasaitis T.
- Vasaitis T. S.
- Vincent C. O. Njar
- Wang Q.
- Watson P. A.
- Wong C.
- Wu Y. L.
- Yamashita K.
- Yamashita S.
- Yang J.
- Yarbrough W. G.
- Zeynep Ates-Alagoz
- Publication venue
- 'American Chemical Society (ACS)'
- Publication date
- Field of study
No full textThe Metabolism, Analysis, and Targeting of Steroid Hormones in Breast and Prostate Cancer
- Author
- A Endoh
- A Gucalp
- A Howell
- A Lai
- A Pont
- AK Kwegyir-Afful
- AM Brodie
- AS Coates
- B Belanger
- B Fisher
- B Montgomery
- B Thurlimann
- BC Chung
- BD Lehmann
- BW O’Malley
- C Arce-Salinas
- C Huggins
- C Huggins
- C Rivier
- C Tran
- CA Hudis
- CD DuSell
- CJ Ryan
- CK Osborne
- CK Osborne
- CM Perou
- D Masiello
- DF Covey
- DF Smith
- DH Geller
- DJ Mangelsdorf
- DR Cochrane
- DR Robinson
- DW Russell
- E Rheaume
- E Rossi
- EA Ariazi
- ED Crawford
- EP Winer
- ER Simpson
- F Labrie
- G Attard
- G Attard
- G Beatson
- GS Chetrite
- H Gronemeyer
- H Sasano
- HI Scher
- HI Scher
- HL Judd
- IE Smith
- IE Smith
- IM Thompson
- J O’Shaughnessy
- J Picado-Leonard
- J Richards
- J Veldscholte
- JD Wilson
- JE Griffin
- JG McDonald
- JJ Cali
- JL Mohler
- JM Beekman
- JM Grodin
- JM Hall
- JM Wurtz
- JS de Bono
- K Evaul
- K Fizazi
- KH Chang
- KH Chang
- KJ Matteson
- LA Paige
- M Costa-Santos
- M Dowsett
- M Dowsett
- M Dumont
- M Garrido
- M Katagiri
- M Lippman
- M Umetani
- M Yamaoka
- MA Eisenberger
- MA Titus
- MD Johnson
- ME Lippman
- MH Gail
- MJ Sikora
- N Orentreich
- N Strushkevich
- O Pagani
- PE Belchetz
- PJ Toren
- PK Siiteri
- PR Dillard
- R Dent
- R Fujii
- R Li
- R Mindnich
- RB Montgomery
- RD Catalano
- RI Nicholson
- RJ Auchus
- RJ Auchus
- RJ Santen
- RJ Santen
- RJ Santen
- RJ Santen
- RR Love
- S Kominami
- SA Wells Jr
- SE Bulun
- SJ Meachem
- SJ Santner
- SM Singh
- T Key
- T Visakorpi
- TA Traina
- TM Beer
- V Luu The
- V Stearns
- VC Jordan
- VD Handratta
- W Toy
- W Vale
- WL Miller
- Y Nakamura
- Z Li
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study
No full textHormone-Based Therapies for Castration-Resistant Prostate Cancer
- Author
- A Godoy
- A Hamada
- A Mizokami
- A Mizokami
- A Molina
- A O’Donnell
- A Srebrow
- AH Reid
- BS Carver
- C Ahlem
- C Changmeng
- C Tran
- CD Chen
- CG Leon
- CJ Ryan
- CJ Ryan
- CJ Ryan
- CW Gregory
- CW Gregory
- D Bauman
- D Rathkopf
- DB Solit
- DC Danila
- DJ Mulholland
- DJ Samson
- DL Marrocco
- DR Bauman
- DR Bauman
- DS Welsbie
- E Greenberg
- E Hornberg
- E Koh
- EA Mostaghel
- EA Mostaghel
- EA Mostaghel
- EJ Small
- EY Yu
- G Attard
- G Attard
- G Emons
- G Forti
- G Marcias
- H Miyamoto
- HI Scher
- HI Scher
- J Geller
- J Geller
- J Geller
- J Geller
- J Holzbeierlein
- J Liu
- J Liu
- J Morote
- J Veldscholte
- JA Locke
- JA Locke
- JA Locke
- JD Wu
- JF Caubet
- JL Mohler
- JL Mohler
- JL Mohler
- JL Thomas
- JL Wright
- JM Day
- JT Arnold
- K Evaul
- K Hashimoto
- K Narimoto
- KH Chang
- M Stanbrough
- M Yang
- MA Leversha
- MC Byrns
- ME Taplin
- ME Taplin
- MM Centenera
- MM Rahman
- MP Steinkamp
- MR Robinson
- N Sharifi
- P Singh
- P Zhu
- PA Watson
- PR Dillard
- Q Ji
- R Chmelar
- R Hu
- R Hu
- RB Montgomery
- RD Bruno
- RJ Andersen
- RJ Auchus
- RS Raddin
- S Sun
- SM Dehm
- ST Page
- SV Liu
- T Koreckij
- T Nishiyama
- T Nishiyama
- T Sillat
- T Vasaitis
- T Visakorpi
- TB Dorff
- TD Koreckij
- TM Morgan
- V Gnanapragasam
- VD Handratta
- Y Li
- Y Liu
- Y Wang
- Z Culig
- Z Culig
- Z Guo
- ZM Zair
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study
No full textTargeting the androgen receptor pathway in castration-resistant prostate cancer: progresses and prospects
- Author
- A Gibbs
- A Godoy
- A Sharma
- A Zoubeidi
- AE Cariaga-Martinez
- AH Reid
- AI O'Donnell
- AJ Schrader
- AO Brinkmann
- B Cinar
- B He
- B Sahu
- Bertrand Tombal
- Bruce Montgomery
- BS Carver
- BS Taylor
- C Cai
- C Geng
- C Huggins
- C Thomas
- CA Heinlein
- CD Chen
- CE Barbieri
- CE Bohl
- CJ Logothetis
- CJ Ryan
- CM Robbins
- CS Grasso
- D Bianchini
- D Bianchini
- DA Wolf
- DC Smith
- DE Rathkopf
- DJ Osguthorpe
- DJ van de Wijngaart
- DN Lavery
- DN Lavery
- DW Russell
- E Unni
- EA Mostaghel
- EA Mostaghel
- EB Askew
- EY Yu
- F Schaufele
- G Attard
- G Attard
- G Attard
- G Attard
- G Castoria
- G Di Lorenzo
- G Jenster
- G Sonpavde
- GA Potter
- GJ Kolvenbag
- GN Brooke
- H Beltran
- HI Scher
- HI Scher
- HI Scher
- J Geller
- J Luo
- J Luo
- J Ni
- J Prescott
- J Richards
- J S de Bono
- J Simard
- J Veldscholte
- J Welti
- JA Locke
- JC Araujo
- JC Brenner
- JD Joseph
- JD Wu
- JI Choi
- JM Grad
- JM Grad
- JM Willder
- JM1 Mosquera
- Joel Robert Eisner
- JP Bergerat
- JS de Bono
- K Coffey
- K Fizazi
- K Haapala
- Karim Fizazi
- KH Chang
- KK Waltering
- KL Noonan
- KM Jozwik
- KM Wiren
- KR Lamont
- L Bubendorf
- L L Liu
- L Zhang
- LA Garraway
- M Jarman
- M Korpal
- M Stanbrough
- M Uemura
- M Verras
- MA Leversha
- MA Titus
- MD Balbas
- MD Michaelson
- ME Jung
- ME Taplin
- ME Taplin
- ME Taplin
- ME van Royen
- MF Berger
- MJ Linja
- MJ Schiewer
- MJ Wallen
- ML Cutress
- MP Steinkamp
- MR Smith
- N Mitsiades
- N Palanisamy
- N Rhodes
- NJ Clegg
- NP Mahajan
- P Koivisto
- P Ravindranathan
- PA Watson
- PC Fong
- PC Lin
- Q Zhu
- R Chmelar
- R Ferraldeschi
- R Ferraldeschi
- R Hu
- R Hu
- RB Montgomery
- RJ Andersen
- RZ Szmulewitz
- S Chen
- S Ha
- S Lu
- S Pacey
- S Signoretti
- S Sun
- SA Tomlins
- SE Barrie
- SE Barrie
- SK Sandhu
- SK Sandhu
- SK Shu
- SM Dehm
- SR Plymate
- T Hara
- T Kaku
- T Okegawa
- T Visakorpi
- TA Yap
- Tomasz M. Beer
- V Georget
- V Laudet
- VD Handratta
- VK Arora
- WL Kraus
- X Jiang
- XY Zhao
- Y Li
- Y Li
- Y Liu
- Y Loriot
- Y Miyoshi
- Y Zhang
- Z Culig
- Z Guo
- Z Guo
- Z Yu
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study
No full text
