Manganese-doped Mesoporous Silica Nanopowder for Pharmaceutical Applications

The purpose of the research was to produce and analyze properties of manganesedoped mesoporous silica nanopowder (NP) for biomedical applications. SiO2-MnO2 NP were produced by pulsed electron evaporation demonstrated high porosity amorphous structure, magnetic properties increased with addition of dopant. The toxicity experiments on cells showed that SiO2-MnO2 NP exerted low toxicity. Loading experiments showed qualitative interaction of antibiotic “Amoxicillin” with NP surface. According to obtained properties, produced SiO2-MnO2mesoporous NP is potential material for creating targeted drug delivering system. Keywords: mesoporous silica nanopowder, doped with manganese dioxide, targeted drug delivery

Investigation of Biological and Photocatalytic Activity of Multimodal Nanopowders Produced by Pulsed Electron Beam Evaporation in Vacuum

Nanopowders doped with silver were produced by the method of pulsed electron beam evaporation. The pore sizes of the nanoparticles were 25-32 nm. Evaluation of photocatalytic and cytotoxic properties on cells was carried out. The prospects of using multimodal nanopowders as a photocatalytic agent, as well as for use in medicine, have been shown. © 2021 Institute of Physics Publishing. All rights reserved.The study was carried out with the financial support of RFFI and the Sverdlovsk region as part of the scientific project № 20-48-660019

LUMINESCENT PROPERTIES OF BaF2-ADDITIVES FOR COMPOSITE SCINTILLATORS

In this work the influence of different synthesis methods on luminescent properties of nanocrystalline BaF2 synthesized by laser ablation and electron beam method, is studied. Normolized and absolute X-ray excited luminescence (XEL) spectra for all samples are presented. XEL spectra contain two emission bands at 222 nm (cross-luminescence band) and at 300 nm caused by self-trapped exciton. Samples obtained by laser ablation method characterized by most effective luminescence intensity

Nanoluminofors Based on Silicates and Germanates of Rare Earth Elements for Visualization of Biotissues

Received: 19.01.2022. Revised: 14.07.2022. Accepted: 14.07.2022. Available online: 19.07.2022.Silicates and germanates of rare earth elements are promising for visualization of biological tissues.Upconversion silicate and germanate nanoluminophores containing Er and Yb ions can be used for optical and X-ray bioimaging.Nanoparticles of silicates and germanates with a general formula Sr2R8–x–yErxYbyM6O26 (R = Y, La; M = Si, Ge) were produced in vacuum by the method of pulse electron beam evaporation. An upconversion photoluminescence of the nanoparticles was detected during the excitation by a laser with a wavelength of 980 nm with a predominance of lines in the red and near infrared regions of the spectrum. Due to their optical properties, the nanoparticles can be excited directly through the biotissues to visualize various pathologies. The obtained nanosamples have K-jumps of X-ray radiation absorption in the 10−100 keV energy region. This opens up prospects for the use of the nanoparticles as X-ray contrast agents. Thus, the nanoparticles have both optical and X-ray contrast characteristics, and therefore have the potential necessary for imaging and diagnosing pathologies in biological tissues.This work was carried out in accordance with the state assignment of the Institute of Solid State Chemistry, Ural Branch of the Russian Academy of Sciences

Influence of Fe-Doping on the Structural and Magnetic Properties of ZnO Nanopowders, Produced by the Method of Pulsed Electron Beam Evaporation

The nanopowders (NPs) ZnO-Zn-Fe and ZnO-Fe with the various concentrations of Fe (xFe) (0≤xFe≤0.619 mass.%) were prepared by the pulsed electron beam evaporation method. The influence of doping Fe on structural and magnetic properties of NPs was investigated. X-ray diffraction showed that powders contain fine-crystalline and coarse-crystalline ZnO fractions with wurtzite structure and an amorphous component. Secondary phases were not found. The magnetic measurements made at room temperature, using the vibration magnetometer and Faraday’s scales, showed ferromagnetic behavior for all powders. Magnetization growth of NPs ZnO-Zn and ZnO-Zn-Fe was detected after their short-term annealing on air at temperatures of 300–500°C. The growth of magnetization is connected with the increase in the concentration of the phase ZnO with a defective structure as the result of oxidation nanoparticles (NPles) of Zn. The scanning transmission electron microscopy (STEM) showed a lack of Fe clusters and uniform distribution of atoms dopant in the initial powder ZnO-Zn-Fe. A lack of logical correlation between magnetization and concentration of a magnetic dopant of Fe in powders is shown