6,827 research outputs found
Alun R. Hughes: Publications and Reports
Bibliography for Alun R. Hughe
Positrons from particle dark-matter annihilation in the Galactic halo: propagation Green's functions
We have made a calculation of the propagation of positrons from dark-matter
particle annihilation in the Galactic halo in different models of the dark
matter halo distribution using our 3D code, and present fits to our numerical
propagation Green's functions. We show that the Green's functions are not very
sensitive to the dark matter distribution for the same local dark matter energy
density. We compare our predictions with computed cosmic ray positron spectra
(``background'') for the ``conventional'' CR nucleon spectrum which matches the
local measurements, and a modified spectrum which respects the limits imposed
by measurements of diffuse Galactic gamma-rays, antiprotons, and positrons. We
conclude that significant detection of a dark matter signal requires favourable
conditions and precise measurements unless the dark matter is clumpy which
would produce a stronger signal. Although our conclusion qualitatively agrees
with that of previous authors, it is based on a more realistic model of
particle propagation and thus reduces the scope for future speculations.
Reliable background evaluation requires new accurate positron measurements and
further developments in modelling production and propagation of cosmic ray
species in the Galaxy.Comment: 8 pages, 6 ps-figures, 3 tables, uses revtex. Accepted for
publication in Physical Review D. More details can be found at
http://www.gamma.mpe-garching.mpg.de/~aws/aws.htm
The Contribution of Different Supernova Populations to the Galactic Gamma-Ray Background
The contribution of Source Cosmic Rays (SCRs), accelerated and still confined
in Supernova Remnants (SNRs), to the diffuse high energy \gr emission above 1
GeV from the Galactic disk is studied. The \grs produced by the SCRs have a
much harder spectrum than those generated by the Galactic Cosmic Rays (GCRs).
Extending a previous paper, a simple SNR population synthesis is considered and
the Inverse Compton emission from the SCR electrons is evaluated in greater
detail. Then the combined spectrum of \gr emission from the Galactic Supernova
Remnant population is calculated and this emission at low Galactic latitudes is
compared with the diffuse \gr emission observed by the EGRET and ground based
instruments. The average contribution of SCRs is comparable to the GCR
contribution already at GeV energies, due to Supernovae of types II and Ib
exploding into the wind bubbles of quite massive progenitor stars, and becomes
dominant at \gr energies above 100 GeV. At TeV energies the dominant
contribution is from SCRs in SNRs that expand into a uniform interstellar
medium. In fact, the sum of hadronic and Inverse Compton \grs would exceed the
limits given by the existing experimental data, unless the confinement time
, i.e. the time until which SNRs confine the main fraction of
accelerated SCRs, is as small as yr and the typical magnetic
field strength in SNRs as large as 30 G. Both situations are however
possible as a result of field amplification through CR backreaction in the
acceleration process. It is pointed out that accurate measurements of the
low-latitude diffuse Galactic \gr spectrum at TeV-energies can serve as a
unique consistency test for CR origin from the Supernova Remnant population as
a whole.Comment: To appear in Astrophysical Journa
UHE nuclei propagation and the interpretation of the ankle in the cosmic-ray spectrum
We consider the stochastic propagation of high-energy protons and nuclei in
the cosmological microwave and infrared backgrounds, using revised photonuclear
cross-sections and following primary and secondary nuclei in the full 2D
nuclear chart. We confirm earlier results showing that the high-energy data can
be fit with a pure proton extragalactic cosmic ray (EGCR) component if the
source spectrum is \propto E^{-2.6}. In this case the ankle in the CR spectrum
may be interpreted as a pair-production dip associated with the propagation. We
show that when heavier nuclei are included in the source with a composition
similar to that of Galactic cosmic-rays (GCRs), the pair-production dip is not
present unless the proton fraction is higher than 85%. In the mixed composition
case, the ankle recovers the past interpretation as the transition from GCRs to
EGCRs and the highest energy data can be explained by a harder source spectrum
\propto E^{-2.2} - E^{-2.3}, reminiscent of relativistic shock acceleration
predictions, and in good agreement with the GCR data at low-energy and holistic
scenarios.Comment: 4 pages, 4 figures, submitted to A&A Letters (minor changes, two
figures replaced, two references added
Multi-wavelength constraints on cosmic-ray leptons in the Galaxy
Cosmic rays (CRs) interact with the gas, the radiation field and the magnetic
field in the Milky Way, producing diffuse emission from radio to gamma rays.
Observations of this diffuse emission and comparison with detailed predictions
are powerful tools to unveil the CR properties and to study CR propagation. We
present various GALPROP CR propagation scenarios based on current CR
measurements. The predicted synchrotron emission is compared to radio surveys,
and synchrotron temperature maps from WMAP and Planck, while the predicted
interstellar gamma-ray emission is compared to Fermi-LAT observations. We show
how multi-wavelength observations of the Galactic diffuse emission can be used
to help constrain the CR lepton spectrum and propagation. Finally we discuss
how radio and microwave data could be used in understanding the diffuse
Galactic gamma-ray emission observed with Fermi-LAT, especially at low
energies.Comment: 8 pages, 5 figures; in Proceedings of the 34th International Cosmic
Ray Conference (ICRC 2015), The Hague (The Netherlands); Oral contributio
Serine hydroxymethyltransferase: origin of substrate specificity
All forms of serine hydroxymethyltransferase, for which a primary structure is known, have five threonine residues near the active-site lysyl residue (K229) that forms the internal aldimine with pyridoxal phosphate. For Escherichia coli serine hydroxymethyltransferase each of these threonine residues has been changed to an alanine residue. The resulting five mutant enzymes were purified and characterized with respect to kinetic and spectral properties. The mutant enzymes T224A and T227A showed no significant changes in kinetic and spectral properties compared to the wild-type enzyme. The T225A and T230A enzymes exhibited differences in K(m) and k(cat) values but exhibited the same spectral properties as the wild-type enzyme. The four threonine residues at positions 224, 225, 227, and 230 do not play a critical role in the mechanism of the enzyme. The T226A enzyme had nearly normal affinity for substrates and coenzymes but had only 3% of the catalytic activity of the wild-type enzyme. The spectrum of the T226A enzyme in the presence of amino acid substrates showed a large absorption maximum at 343 nm with only a small absorption band at 425 nm, unlike the wild-type enzyme whose enzyme-substrate complexes absorb at 425 nm. Rapid reaction studies showed that when amino acid substrates and substrate analogues were added to the T226A enzyme, the internal aldimine absorbing at 422 nm was rapidly converted to a complex absorbing at 343 nm in a second-order process. This was followed by a very slow first-order formation of a complex absorbing at 425 nm. Variation of the initial rapid second-order process as a function of pH suggested that the anionic form of the amino acid forms the first complex with the enzyme. The results are interpreted as being due to the rapid formation of a gem-diamine complex between amino acids and T226A enzyme with a rate-determining formation of the external aldimine. This suggests that Thr-226 plays an important role in converting the gem-diamine complex to the external aldimine complex. Variation of the kinetic constants with amino acid structure suggests that the T226A enzyme distinguishes between substrates and substrate analogues in the formation of the gem-diamine complex
Effective chiral-spin Hamiltonian for odd-numbered coupled Heisenberg chains
An system of odd number of coupled Heisenberg spin chains
is studied using a degenerate perturbation theory, where is the number of
coupled chains. An effective chain Hamiltonian is derived explicitly in terms
of two spin half degrees of freedom of a closed chain of sites, valid in
the regime the inter-chain coupling is stronger than the intra-chain coupling.
The spin gap has been calculated numerically using the effective Hamiltonian
for for a finite chain up to ten sites. It is suggested that the
ground state of the effective Hamiltonian is correlated, by examining
variational states for the effective chiral-spin chain Hamiltonian.Comment: 9 Pages, Latex, report ICTP-94-28
Prodigious polyphyly in Pleuroceridae (Gastropoda: Cerithioidea)
Phylogenomic studies with hundreds or thousands of loci are rare for most invertebrate groups, including freshwater gastropods. This can prevent understanding of phylogeny, which hinders many areas of research. Pleuroceridae is a family of freshwater snails that is highly imperiled and plays an essential role in the ecology of many freshwater systems of the eastern United States. However, the evolutionary history of the family is not understood, and the systematics of the family has not been revised in a modern framework. Pleurocerids display a variety of egg-deposition behaviors and shell shapes, making the family an ideal system for studying evolution of invertebrate life history and morphology. However, past mitochondrial-based phylogenetic analyses have failed to produce meaningful phylogenetic hypotheses, preventing conclusions about pleurocerid systematics and evolution. Here, we generated a novel anchored hybrid enrichment probe set with phylogenetic utility for Pleuroceridae. We sampled pleurocerids from across their range to test the probe set and generated a backbone phylogeny. Our analyses uncovered striking levels of polyphyly among currently accepted genera. Numerous species were also polyphyletic, indicative of unrecognized diversity. Phylogenetic patterns also revealed considerable convergence of shell morphologies. In contrast, anatomical and life history features appeared to be much less homoplastic. Despite generic paraphyly, high support for most major clades and phylogenetic cohesiveness of non-shell characters indicate utility of the AHE probe set for studying pleurocerid evolution
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