129 research outputs found

    Developing Framework for the Implementation of Advanced Manufacturing Technologies in Small and Medium-Sized Enterprises

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    Intense competition, demanding customers, and shortening product life cycles are prompting small- and medium-sized enterprises to invest in advanced manufacturing technologies (AMTs). Small manufacturers often depend on large manufacturers for orders and so require design as well as manufacturing flexibility on their part. One way of achieving the flexibility is through adoption of AMTs. The decision to invest in AMT is a major decision and thus requires proper consideration to all the aspects of the implementation process before a final commitment is made. Although the technical capabilities of AMTs are well proven, neither practitioner nor academics agree upon a framework for its successful implementation. Using Churchill’s model (Steps 1 and 2) and drawing a link from the available literature, a theoretical framework is developed for the successful implementation of AMTs in small- and medium-sized enterprises. Three implementation phases—namely, planning, preimplementation, and postimplementation—with 14 major issues have been developed; 52 constituent factors have been identified from these issues through literature review and interviews with industry professionals

    Application of DIC in Solid Mechanics

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    During service life, composite structures are susceptible to damage which reduces their structural integrity. For improved service life, the damage needs to be repaired. In case of low velocity impact damage adhesively bonded patch repair has shown to be cost effective and most efficient in extending service life of damaged parts. The repair performance is mainly influenced by patch stacking sequence, patch shape, patch thickness, overlap length and adhesive strength. In the first phase of work, a 3D finite element based study is carried out using mechanics based approach to optimize the patch dimensions and stacking sequence so that the performance of repaired structure can be improved. Also, a genetic algorithm based approach in-conjunction with finite element analysis is implemented for arriving at an optimized patch and adhesive dimensions. Experimental study is then carried out with optimized geometry using non-contact optical based technique namely digital image correlation (DIC). The mechanics of double and single sided repair are discussed in detail and strain field from DIC have been compared with finite element (FE) estimates

    Theoretical Design of the Experiment to Study Scattering of Electrons and Positrons by Electrons

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    A User Oriented Image Retrieval System using Halftoning BBTC

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    The objective of this paper is to develop a system for content based image retrieval (CBIR) by accomplishing the benefits of low complexity Ordered Dither Block Truncation Coding based on half toning technique for the generation of image content descriptor. In the encoding step ODBTC compresses an image block into corresponding quantizes and bitmap image. Two image features are proposed to index an image namely co-occurrence features and bitmap patterns which are generated using ODBTC encoded data streams without performing the decoding process. The CCF and BPF of an image are simply derived from the two quantizes and bitmap respectively by including visual codebooks. The proposed system based on block truncation coding image retrieval method is not only convenient for an image compression but it also satisfy the demands of users by offering effective descriptor to index images in CBIR system

    Compositional alterations in erythrocyte membranes in Type II diabetes

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    Loss of erythrocyte membrane deformability is one of the most crucial factors in developing complications associated with Type II diabetes. The observed loss of erythrocyte membrane deformability could be related to structural changes in the membrane. In this context, here, we have made an attempt at gaining a better insight (quantitative as well as qualitative) into the protein and lipid contents in erythrocyte membranes and their interrelationships in Type II diabetes. Age matched control (n=12) and Type II diabetic subjects (n=22) were selected for this study. Morphological characteristics were studied by atomic force microscopy (AFM). AFM study confirmed remarkable alterations in morphology of the diabetic erythrocytes. In diabetic erythrocytes following changes were noted: (i) Significant increase in membrane as well as cytosolic proteins with a marginal increase in phospholipids content; (ii) The membrane total lipids:protein, phospholipids:protein, cholesterol:protein and phospholipids:cholesterol (mole:mole) ratios decreased significantly; (iii). A reproducible decrease in docosahexaenoic acid (DHA) and Omega-3 index with increase in Omega-6:Omega-3 ratio in membrane fatty acids; and (iv) The SDS-PAGE analysis indicated that all membrane proteins increased in almost equal proportion leading to increased membrane protein content. The observed compositional and stochiometric changes in lipids, proteins and their ratios may underlie morphological alterations and loss of deformability

    Compositional alterations in erythrocyte membranes in Type II diabetes

    Get PDF
    671-679Loss of erythrocyte membrane deformability is one of the most crucial factors in developing complications associated with Type II diabetes. The observed loss of erythrocyte membrane deformability could be related to structural changes in the membrane. In this context, here, we have made an attempt at gaining a better insight (quantitative as well as qualitative) into the protein and lipid contents in erythrocyte membranes and their interrelationships in Type II diabetes. Age matched control (n=12) and Type II diabetic subjects (n=22) were selected for this study. Morphological characteristics were studied by atomic force microscopy (AFM). AFM study confirmed remarkable alterations in morphology of the diabetic erythrocytes. In diabetic erythrocytes following changes were noted: (i) Significant increase in membrane as well as cytosolic proteins with a marginal increase in phospholipids content; (ii) The membrane total lipids:protein, phospholipids:protein, cholesterol:protein and phospholipids:cholesterol (mole:mole) ratios decreased significantly; (iii). A reproducible decrease in docosahexaenoic acid (DHA) and Omega-3 index with increase in Omega-6:Omega-3 ratio in membrane fatty acids; and (iv) The SDS-PAGE analysis indicated that all membrane proteins increased in almost equal proportion leading to increased membrane protein content. The observed compositional and stochiometric changes in lipids, proteins and their ratios may underlie morphological alterations and loss of deformability
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