A successful pregnancy outcome: post bilateral salphingo-oophorectomy

A 30 year old nulliparous woman, married for 7 years presented with complaints of lower abdominal pain since a year. Her menstrual history has been regular, associated with dysmenorrhea. She gave a past surgical history of right ovarian cystectomy in view of chocolate cyst noted on diagnostic laparoscopy. Investigations revealed a bilateral complex ovarian cyst and an elevated Ca-125 of 100 units/ml, proceeded with bilateral salphingo-oopherectomy as grade IV endometrioma of both ovaries with frozen pelvis noted. Later, she resumed her menstrual cycles with exogenous estrogen and progesterone. She conceived following a donor oocyte frozen embryo transfer and she delivered a healthy 2.74 kg girl baby with a good Apgar score

Effects of salinity on the growth, photosynthesis and mineral constituents of the mangrove Rhizophora apiculata L. seedlings

The effects of salinity on growth, chlorophyll content, photosynthetic rates, as measured by leaf stomatal conductance and leaf chlorophyll fluorescence induction, and ion accumulation in the mangrove plant Rhizophora apiculata were determined. The following questions were addressed:                (1) What effect does salinity have on growth responses at different ages? (2) Is R. apiculata an ion accumulator? (3) Does R. apiculata accumulate chlorophyll, net photosynthesis and chlorophyll fluorescence in response to salinity? Rhizophora apiculata  plants were grown in pots at 0, 25, 50, 75 and 100 % in sand culture in a plant growth chamber and plants were harvested after 30 and 90 d. Plant total fresh and dry weight and moisture content was significantly inhibited at 75 per cent seawater. Seawater salinity stimulated the chlorophyll contents and they were increased upto 75 per cent seawater.  The net photosynthesis increased with increasing salinity upto the optimal level and the CO2 uptake rate was identical in this species at various salt concentrations. Even at extreme salinity, the CO2 uptake was comparable to that non-saline control plants and CO2 uptake could be correlated with the chlorophyll content. The photochemical activities such as PSI and PSII of the isolated cells increased upto the optimal salinity. The result of the chlorophyll fluorescence kinetics provided with additional proof to the finding of CO2 exchange rate and photochemical activities.  The Na+ and Cl− content in both shoots and roots increased with increases in salinity. Increased treatment levels of NaCl induced decreases in Ca+, P, K+, Mg+   and N in plants

New validated RP-HPLC method for simultaneous estimation of chlorpromazine and trihexyphenidyl HCl in tablets

A simple, specific and precise reverse phase high performance liquid chromatographic method was developed and validated for simultaneous estimation of Chlorpromazine and Trihexyphenidyl HCl in tablets. Quantification was achieved by using a reverse-phase C18 column (Inertsil ODS 3V, 250 mm x 4.6 mm; 5) at 31 o C. The mobile phase consisted of a mixture of ammonium acetate buffer and methanol in the ratio of 15:85 v/v at a flow rate of 1.2 mL/min. The retention times of Chlorpromazine and Trihexyphenidyl HCl were found to be 3.237 min and 5.260 min respectively. The developed method was validated as per ICH Guidelines for linearity, accuracy, precision, detection limit, quantification limit, ruggedness, robustness, specificity and system suitability. The percentage recoveries for both of the drugs from their tablets were found to be 100.34 % and 99.80 % respectively. The method may successfully be employed for the simultaneous determination of Chlorpromazine and Trihexyphenidyl HCl in pharmaceutical tablet dosage forms

A Novel Algorithm for Discovering Frequent Closures and Generators

The Important construction of many association rules needs the calculation of Frequent Closed Item Sets and Frequent Generator Item Sets (FCIS/FGIS). However, these two odd jobs are joined very rarely. Most of the existing methods apply level wise Breadth-First search. Though the Depth-First search depends on different characteristics of data, it is often better than others. Hence, in this paper it is named as FCFG algorithm that combines the Frequent closed item sets and frequent generators. This proposed algorithm (FCFG) extracts frequent itemsets (FIs) in a Depth-First search method. Then this algorithm extracts FCIS and FGIS from FIs by a level wise approach. Then it associates the generators to their closures. In FCFG algorithm, a generic technique is extended from an arbitrary FI-miner algorithm in order to support the generation of minimal non-redundant association rules. Experimental results indicate that FCFG algorithm performs better when compared with other level wise methods in most of the cases

Case report on perioperative management of combined factor V and VIII deficiency in a patient with prolapse uterus

Combined factor V and factor VIII deficiency is a rare autosomal recessive disorder with incidence of one in 10,00,000. We reported a case of seventy-one-year-old patient with third degree uterovaginal prolapse, diagnosed as combined factor V and VIII deficiency and the successful perioperative management during vaginal hysterectomy. With our experience in this, we conclude that for the patient's with factor V and VIII deficiency that the correction should be given for at least 2 weeks post operatively

Antibacterial Activity of Salicornia brachiata, A Halophyte

Antibacterial activity of Salicornia brachiata was studied by the agar diffusion and dilution methods.  The methanolic extract of leaves of this species was more active than the aqueous extracts against Bacillus subtilis, Bacillus pumilus, Micrococcus luteus and Staphylococcus aureus.ÂÂ

Screening of rhizobacteria containing plant growth promoting (PGPR) traits in rhizosphere soils and their role in enhancing growth of pigeon pea

Plant growth promoting rhizobacteria (PGPR) are beneficial bacteria that colonize plant roots and enhance plant growth with a wide variety of mechanisms. The use of PGPR is steadily increasing in agriculture and offers an attractive way to replace chemical fertilizers, pesticides and supplements. Here, we have isolated, enumerated and characterized the PGPR from the rhizosphere soil of pigeon pea for the enhancement of growth of pigeon pea. Rhizosphere soils were collected from different areas of Samalkot, Pithapuram, Peddapuram and Kakinada. Sixty five (65) isolates were identified and characterized for their morphological, cultural, staining and biochemical characteristics, of which 35 was selected for the screening of PGPR isolates. Sixteen isolates were successfully characterized for the PGPR traits like indole acetic acid (IAA) production, phosphorus solubilization, and production of enzymes like urease, chitinase, amylase, cellulase, protease and β-1,3 glucanase and were assayed. The antagonistic nature of these strains towards fungi and bacteria were estimated by siderophore estimation, 1-amino-cyclopropane-1-carboxylate (ACC) deaminase characterization, dual plate culture method and HCN production technique, and the best one was selected. These were further investigated to show the PGPR traits in pigeon pea seedling emergence, increase of shoot length, root length, dry matter production of shoot, nodule number and nodule mass. Furthermore, PGPR isolates remarkably increased seed germination of pigeon pea. Among the sixteen isolates, seven were found to be highIAA producing. Six were found to be efficient phosphate solubilizers, five isolates were found to be good antagonistic towards pathogen soil fungi and eight isolates were found to be better in enzyme productions, and thus, may enhance the mineralization efficiency of soils. Three isolates were shown to be promising in IAA production, phosphate solubilization, antagonism towards fungi, and mineralizing capacity. Thus, this study suggests the use of these isolates as inoculant biofertilizers which might be beneficial for pigeon pea cultivation as they enhanced the growth and other growth parameters.Keywords: Indole acetic acid (IAA), plant growth promoting rhizobacteria (PGPR), phosphorus solubilization, enzyme productions, seed germinatio

Spontaneous broad ligament haematoma following a normal vaginal delivery: a case report

Broad ligament haematoma is a rare complication following a normal vaginal delivery. We report one such case of a woman who developed this complication within 3 hrs of normal vaginal delivery. She is G2P1L1, 38 wks GA, in active labour. Pt was allowed for spontaneous progression of labour, following which she delivered vaginally. Within 3 hrs patient looked clinically very pale with vitals being deranged and complains of inability to void urine, severe perineal pain. On basis of clinical examination and transabdominal ultrasound features a diagnosis of right sided broad ligament haematoma was made. Based on patients haemodynamic instability surgical management in the form of obstetric hysterectomy was done

In situ measurement and management of soil, air, noise and water pollution in and around the Limestone mining area of Yerraguntla, YSR kadapa, Andhra Pradesh, India for the sustainable development

For emerging countries, mining has been a vital factor in employment, economic development, infrastructure, and supply of essential raw materials for Nation’s Gross domestic product (GDP) growth. The Limestone mine industry is serving as a viable route for economic transformation in India.  Limestone exploration causes major damage to the environment at Yerraguntla industrial zone, YSR Kadapa district, Andhra Pradesh, India. The main objective of this study is to evaluate the environmental Pollution parameter that causes Air, Water, Noise, and Soil pollution in and around limestone quarries started in the early 1984. The present study estimated Air Quality Index (AQI) as 76 based on the air quality sub-index approach using four pollutants (PM10, PM2.5, SO2, NOx) for a period of 24 hrs by taking one sample per hour during the post monsoon. Water Quality Index (WQI) obtained as 303.91 from fourteen physicochemical parameters (pH, EC, fluoride, Total alkalinity etc.) measured from water samples. Soil quality was determined using four physicochemical parameters (pH, EC, WHC, Calcium and Magnesium) from the soil samples collected from ten sampling stations. The obtained pH range was (7.6 to 9.4), EC of the soil was determined as 4,140 µs/cm, the water retention capacity of the soil, ranges from (17.68 to 97.68) %, and the Calcium (Ca2+) and Magnesium (Mg2+) ranged from 74.5 to 272.75 mEq/L. Noise levels were determined as 76.64 dB in the mine’s, 58.16 dB in the cement industry, and 52.285 dB in the mine surrounding villages. This study can help mining sector management’s in developing a sustainable Environmental Management frame work to meet the world sustainable development goals  (SDGs)

Oxygen delivery system in pre-hospital emergency care in india GVK EMRI 108: a review article

The goal of an effective emergency medical system should be to provide universal emergency care along with assured quality. Oxygen is often used drug in the pre hospital. Oxygen delivery can be monitored by pulse oximetry, typically with a goal of reversing hypoxemia. This paper describes the importance of oxygen in emergency care and its contribution to reducing avoidable death and disability. It also highlights the oxygen delivery systems and training processes /protocols in ambulance based pre-hospital care. In addition, it also shares the usage rates of oxygen and delivery methods in thermal and electrical burns in 108 GVK EMRI, India ambulances. A descriptive study methodology was adopted for explaining the training and pre-hospital care processes of oxygen delivery. Retrospective study method was adopted to measure the oxygen utilization rates in management of burns cases in 108 ambulances in the year 2015. EMTs consistently assessed vitals and provided oxygen to patients’. When EMTs found that patients’ had oxygen saturation less than 95%, they provided supplemental oxygen 95% of the times. EMTs though adhering to the routine use of oxygen in 9 out of 10 cases “where indicated, refresher training should focus on use of oxygen in special circumstances and the benefit to be closely monitored for favourable clinical outcomes”. There is a need to study such common and important essential pre-hospital interventions in all types of emergencies being served