Determination of some heavy metals (Cd, Cu, Pb, Zn) in breeding sheep tissues with parasitisms, soil, water and feedstuffs of around environment in industry in Kırıkkale

Bu çalışma Kırıkkale’de petrol rafineri ve silah fabrikaları çevresinde yetiştirilen koyunların çeşitli dokularında, bu koyunlarda bulunan parazitte (kist hidatik), yem, su ve toprakta bazı ağır metal düzeylerinin belirlenmesi amaçlanmıştır. Endüstri bölgesindeki bitki, toprak ve sudaki kadmiyum düzeyi ortalamaları arasında anlamlı fark tespit edilmemiştir. Değişik mesafelerden örneklenen yeşil vejetasyonda bakır düzeyleri ortalamaları benzerlik gösterirken bu ortalamanın kuru vejetasyon yemlerinde ve toprakta endüstri bölgesinin 20.km deki mesafede en yüksek seviyede, 5. ve 3. km ise en düşük seviyede olduğu gözlenmiştir. Sudaki bakır düzeyi ise tespit edilebilir sınırların (LoD) altında bulunmuştur. Endüstri bölgesine en yakın olan yerdeki yeşil vejetasyon örneklerinin kurşun düzeyleri diğer örnekleme bölgelerden elde edilenlere kıyasla yaklaşık 2 kat yüksek çıkmış ancak istatistiksel anlamlılık tespit edilmemiştir. Toprakta kurşun birikiminin endüstri bölgesinde kontrol örneklerinden anlamlı olarak daha yüksek olduğu tespit edilmiştir (p0,05). Endüstri bölgesindeki vejetasyon örneklerinde çinko düzeyleri benzer bulunmuştur. Ancak endüstri bölgesine en yakın ve en uzak mesafedeki toprak örneklerinde çinko düzeyi orta mesafedekilerden istatistiksel olarak daha yüksek bulunmuştur (p0,05). Analiz edilen verilere göre kist hidatik ile konak dokuları arasında ağır metal birikimi bakımından Cu, Pb ve Zn’da anlamlı ilişki gözlenmiştir.With this project, it was aimed to determine the effects of industrial pollution on sheep tissues, their parasites (cyst hydatic) and their feedstuffs, soil and water samples. No differences were detected in the dry vegetation, soil and water cadmium levels among the locations. Average level of Copper (Cu) in dry vegetation and soil samples collected in the areas 20 km far from industrial region was found to be higher when compared with the samples collected from 5. ve 3. km far from industrial areas. However, Cu level was found to be under detectable limits in the water. Mean lead concentrations of the green vegetation samples collected from the closest location was twice as high as those of samples collected from other areas, however, there was no significant difference. It was determined that accumulation of lead in soils collected from 3 consecutive areas close by the plants were significantly higher than that of control area (p<0,05). Zinc concentrations in vegetation samples in industrialized area were similar. In contrast, zinc levels of soil samples in the closest and farest area were significantly higher than those in the middle (p<0,05). In response to the analysed data, it was determined that Cu, Pb and Zn concentrations in tissue and cyst hydatic were significantly related

The synthesis and investigation of the antimicrobial activity of some new phenylselanyl-1-(toluene-4sulfonyl)-1H-tetrazole derivatives

The sulfonamide functional group has aroused interest in both medicinal and bioorganic chemistry. In this study, some new phenylselanyl-1-(toluene-4-sulfonyl)-1H-tetrazole derivatives (2a-f) have been synthesized using dicyclohexylcarbodiimide/dimethylaminopyridine (DCC/DMAP). The structures of the presently synthesized compounds were elucidated by spectroscopic methods [Fourier-transform infrared (FTIR) spectroscopy, (1)H nuclear magnetic resonance (NMR), (13)C nuclear magnetic resonance-attached proton test ((13)C NMR-APT), and mass spectrometry (MS)]. In addition, the antimicrobial activity of the synthesized compounds and two antibiotics [sulfamethoxazole (SMX) and sulfamerazine (SRZ)] were investigated against some microorganisms