14 research outputs found
La influencia de la comunicaci?n en redes sociales y el valor de marca sobre la intenci?n de matr?cula a una universidad
Objetivo: Evaluar c?mo influyen los factores del Valor de Marca y la Comunicaci?n en redes sociales sobre la intenci?n de estudiantes de matricularse en una universidad. Metodolog?a: Se aplicaron encuestas en l?nea a estudiantes de 1er ciclo de universidades de Santiago de Surco (Lima, Per?). Los datos se analizaron mediante regresi?n m?ltiple en SPSS. Valor: Este estudio es una de las primeras aproximaciones al an?lisis de la influencia del valor de marca en conjunto con la comunicaci?n en redes sociales sobre la intenci?n de matricularse en una universidad. Resultados y conclusiones: Factores del valor de marca (Calidad/Liderazgo de Marca y Asociaciones de marca), contenido generado por el usuario (Ewom) y contenido generado por la universidad en redes sociales (Entretenido e Informativo) influyen en la intenci?n de matricularse en la universidad, el ewom fue el factor que m?s influy?. Contenido generado por la universidad Entretenido y que no propague Antivalores influye en el Ewom, contenido Informativo y Entretenido influye en la Calidad/Liderazgo de Marca y Asociaciones de marca. Implicaci?n pr?ctica: La investigaci?n indica que el contenido generado por una universidad en redes sociales debe ser entretenido e informativo y que debe buscar promover el Ewom. Limitaciones y sugerencias: La muestra se enfoc? en estudiantes de universidades de un solo distrito de Lima por lo que los resultados no son generalizables al pa?s y se sugiere incluir otras ?reas geogr?ficas en el futuro
Incidence, risk factors, and impact on mortality of status epilepticus in sepsis in the United States
Incidence, risk factors, and impact on hospital mortality of status epilepticus after subdural hemorrhage in the United States
Diagnostic Accuracy of Procalcitonin in Differentiating Sepsis from Noninfectious SIRS in Adult Patients with Subarachnoid Hemorrhage
Background: Subarachnoid hemorrhage (SAH) is a frequent diagnosis in the neuro-intensive care unit (NICU) that can result in the development of systemic inflammatory response syndrome (SIRS) and fever. The differentiation between central fever and infectious fever is paramount in order to prevent superfluous diagnostic testing and overuse of empiric antibiotics.
Methods: A prospective chart review study conducted in the NICU between December 2012 and September 2015. Patients with SAH, fever (≥101.0°F) and/or who were SIRS positive and had PCT levels measured were included. The primary outcome was clinical infection defined as any positive culture or infiltrate on chest X-ray within three days of onset of fever.
Results: Out of 129 patients, 54 were positive for any culture: 14 with PCT ≤0.2, 12 with PCT \u3e0.2 and ≤0.5, and 28 with PCT \u3e0.5. Using multiple logistic regression, PCT between 0.2-0.5 had an odds ratio of 2.99 (95% CI 1.12-8.00) while PCT \u3e0.5 had an odds ratio of 29.11 (CI 8.49-99.83) and p-value of \u3c0.001. All other predictors were not statistically significant. For procalcitonin \u3e0.5, specificity is 94.7%, sensitivity 51.9%, positive predictive value 87.5%, and negative predictive value 73.2%. ROC Curve area: 79.3%.
Conclusion: PCT of 0.5 ng/mL or greater was useful for distinguishing infectious from central fever in SAH patients, with PCT values between 0.2-0.5 as somewhat predictive of infection. The test has high specificity and a reasonably high negative predictive value, so it can be a valuable tool to rule out infectious fever in patients with SAH
Quality and effectiveness of osteoporosis treatment decision aids: a systematic review and environmental scan
Decision aids (DAs) are evidence-based tools that support shared decision-making (SDM) implementation in practice; this study aimed to identify existing osteoporosis DAs and assess their quality and efficacy; and to gain feedback from a patient advisory group on findings and implications for further research. We searched multiple bibliographic databases to identify research studies from 2000 to 2019 and undertook an environmental scan (search conducted February 2019, repeated in March 2020). A pair of reviewers, working independently selected studies for inclusion, extracted data, evaluated each trial’s risk of bias, and conducted DA quality assessment using the International Patient Decision Aid Standards (IPDAS). Public contributors (patients and caregivers with experience of osteoporosis and fragility fractures) participated in discussion groups to review a sample of DAs, express preferences for a new DA, and discuss plans for development of a new DA. We identified 6 studies, with high or unclear risk of bias. Across included studies, use of an osteoporosis DA was reported to result in reduced decisional conflict compared with baseline, increased SDM, and increased accuracy of patients’ perceived fracture risk compared with controls. Eleven DAs were identified, of which none met the full set of IPDAS criteria for certification for minimization of bias. Public contributors expressed preferences for encounter DAs that are individualized to patients’ own needs and risk. Using a systematic review and environmental scan, we identified 11 decision aids to inform patient decisions about osteoporosis treatment and 6 studies evaluating their effectiveness. Use of decision aids increased accuracy of risk perception and shared decision-making but the decision aids themselves fail to comprehensively meet international quality standards and patient needs, underpinning the need for new DA development
Shared Decision Making Tools for People Facing Stroke Prevention Strategies in Atrial Fibrillation: A Systematic Review and Environmental Scan.
OBJECTIVE: Shared decision making (SDM) tools can help implement guideline recommendations for patients with atrial fibrillation (AF) considering stroke prevention strategies. We sought to characterize all available SDM tools for this purpose and examine their quality and clinical impact. METHODS: We searched through multiple bibliographic databases, social media, and an SDM tool repository from inception to May 2020 and contacted authors of identified SDM tools. Eligible tools had to offer information about warfarin and ≥1 direct oral anticoagulant. We extracted tool characteristics, assessed their adherence to the International Patient Decision Aids Standards, and obtained information about their efficacy in promoting SDM. RESULTS: We found 14 SDM tools. Most tools provided up-to-date information about the options, but very few included practical considerations (e.g., out-of-pocket cost). Five of these SDM tools, all used by patients prior to the encounter, were tested in trials at high risk of bias and were found to produce small improvements in patient knowledge and reductions in decisional conflict. CONCLUSION: Several SDM tools for stroke prevention in AF are available, but whether they promote high-quality SDM is yet to be known. The implementation of guidelines for SDM in this context requires user-centered development and evaluation of SDM tools that can effectively promote high-quality SDM and improve stroke prevention in patients with AF
Variación de salinidad afecta ritmo de crecimiento poblacional y capacidad reproductiva de Brachionus plicatilis: un enfoque al cambio climático
Revista Iberoamericana De BioeconomÃa Y Cambio Climático E-ISSN 2410-7980, 7(14), 1587-1599El objetivo del presente estudio consistió en evaluar, en condiciones de no aclimatación, el ritmo de crecimiento poblacional y la capacidad reproductiva de Brachionus plicatilis, tras el sometimiento a estrés por salinidad reducida. El dÃa del experimento se colocaron en una baterÃa de cuatro grupos experimentales (1: aclimatados y 3: sin aclimatar): grupo control (35 ‰), Tratamiento 1 (25 ‰), Tratamiento 2 (10 ‰) y Tratamiento 3 (7 ‰), N= 30 rot/ml. Se usó agua destilada para reducir la salinidad. Los rotÃferos se cultivaron a temperatura de 31±1ºC, pH 8.33 y se alimentaron con una única dosis de Saccharomyces cerevisiae (1 x 106 cel/ml). Se utilizó aireación constante durante todo el experimento. Los rotÃferos se contaron una vez al dÃa. Los resultados muestran que los rotÃferos cultivados en las salinidades de 35 ‰ y 25 ‰ presentan mayor ritmo de crecimiento poblacional y capacidad reproductiva que los cultivados en 10 y 7 ‰, durante los dos dÃas de estudio. Asimismo, a 35 ‰ se corresponden los mayores valores de tasa de crecimiento (K: 1.66) y rendimiento (r: 129), seguido de 25 ‰. No obstante, en 25 ‰ se observó la mayor cantidad de rotÃferos en etapa reproductiva (96 % de rotÃferos con huevos y valor de Ãndice reproductivo de 0.964). Por consiguiente, nuestros resultados muestran que B. plicatilis, cuando está cultivado en agua marina (35 ‰) y se traslada sin previa aclimatación a medios con salinidad reducida disminuye su tasa de crecimiento y rendimientoUNAN-León, Escuela de ciencias agrarias y veterinarias/ Departamento de AgroecologÃa/Centro de Investigación en Bioeconomia y Cambio climatic
Discovery of a rapidly evolving yeast defense factor, KTD1, against the secreted killer toxin K28
Recommended from our members
A haploid genetics toolbox for Arabidopsis thaliana.
Genetic analysis in haploids provides unconventional yet powerful advantages not available in diploid organisms. In Arabidopsis thaliana, haploids can be generated through seeds by crossing a wild-type strain to a transgenic strain with altered centromeres. Here we report the development of an improved haploid inducer (HI) strain, SeedGFP-HI, that aids selection of haploid seeds prior to germination. We also show that haploids can be used as a tool to accelerate a variety of genetic analyses, specifically pyramiding multiple mutant combinations, forward mutagenesis screens, scaling down a tetraploid to lower ploidy levels and swapping of nuclear and cytoplasmic genomes. Furthermore, the A. thaliana HI can be used to produce haploids from a related species A. suecica and generate homozygous mutant plants from strong maternal gametophyte lethal alleles, which is not possible via conventional diploid genetics. Taken together, our results demonstrate the utility and power of haploid genetics in A. thaliana