Electric Dipole Transitions for some Excited States in Neutral Silver

For some excited levels, transition energies, wavelengths, oscillator strengths and transition probabilities calculations in neutral silver (Ag I) have been calculated within the framework multiconfiguration Hartree-Fock approximation with relativistic corrections (Breit-Pauli Hamiltonian). The wavefunctions and some relativistic corrections have been obtained using MCHF + BP atomic package. Comparisons with other some calculations and experiments are presented

Multiple endobronchial lipomas which were treated by bronchoscopical resection

SummaryBronchial benign tumors are very rare; however, endobronchial lipomas are responsible for 0.1–0.5% of all lung tumors (1,2). Clinical symptoms depend on the severity of bronchial obstruction and the effects on parenchyma. It is more common in men and more frequently observed in the right bronchial system (3). We present a 76-year-old woman with two separate endobronchial lipomas in the upper lobe and intermediary bronchi, who applied with cough and sputum. The patient was successfully treated with electrocautery snare technique. After this procedure, thorax CT showed bronchiectasis of right lower zone. Thoracotomy was not taken into consideration. After 2-year follow-up the patient has no complaint

The cientificWorldJOURNAL Research Article Diffuse Alveolar Damage of the Lungs in Forensic Autopsies: Assessment of Histopathological Stages and Causes of Death

Introduction. Diffuse alveolar damage (DAD) is a morphological prototype of acute interstitial pneumonia. Hospital autopsies or open-lung biopsies are used to monitor common alveolar damage and hyaline membrane (HM) development histopathologically. The aim of this study was to detect histopathological profiles and frequency of DAD and HM in adult forensic autopsies. Materials and Methods. In total, 6813 reports with histopathological samples in 12,504 cases on which an autopsy was performed between 2006 and 2008 were investigated. Sixty-six individuals >18 years of age who were diagnosed with DAD were included. Hematoxylin-and eosin-stained lung preparations were reexamined in line with the 2002 American Thoracic Society/European Respiratory Society idiopathic interstitial pneumonia consensus criteria. Results. Histopathological examination revealed that 50 cases (75.7%) were in the exudative phase and 16 (24.2%) were in the proliferative phase. Only the rate of alveolar exudate/oedema in exudative phase cases (P = 0.003); those of alveolar histiocytic desquamation (P = 0.037), alveolar fibrosis (P = 0.017), chronic inflammation (P = 0.02), and alveolar fibrin (P = 0.001) in proliferative cases were significantly higher. The presence of alveolar fibrin was the only independent variable in favour of proliferative cases (P = 0.016). Conclusion. The detection of all DAD morphological criteria with the same intensity is not always possible in each case. Forensic autopsies may provide a favourable means for expanding our knowledge about acute lung damage, DAD, and interstitial lung disease

Diagnostic value of endobronchial ultrasound-guided transbronchial needle aspiration in various lung diseases

Objective: Endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) is a new method for the diagnosis and staging of lung disease, and its use is increasing worldwide. It has been used as a means of diagnosing lung cancer in its initial stages, and there are data supporting its use for the diagnosis of benign lung disease. The aim of this study was to share our experience with EBUS-TBNA and discuss its diagnostic value. Methods: We retrospectively analyzed the results related to 159 patients who underwent EBUS-TBNA at our pulmonary medicine clinic between 2010 and 2013. We recorded the location and size of lymph nodes seen during EBUS. Lymph nodes that appeared to be affected on EBUS were sampled at least twice. We recorded the diagnostic results of EBUS-TBNA and (for cases in which EBUS-TBNA yielded an inconclusive diagnosis) the final diagnoses after further investigation and follow-up. Results: We evaluated 159 patients, of whom 89 (56%) were male and 70 (44%) were female. The mean age was 54.6 ± 14.2 years among the male patients and 51.9 ± 11.3 years among the female patients. Of the 159 patients evaluated, 115 (84%) were correctly diagnosed by EBUS. The diagnostic accuracy of EBUS-TBNA was 83% for benign granulomatous diseases and 77% for malignant diseases. Conclusions: The diagnostic value of EBUS-TBNA is also high for benign pathologies, such as sarcoidosis and tuberculosis. In patients with mediastinal disorders, the use of EBUS-TBNA should be encouraged, primarily because it markedly reduces the need for mediastinoscopy

Low frequency of p53 and k-ras codon 12 mutations in non-small cell lung carcinoma (NSCLC) tumors and surgical margins

Aims and background: Lung cancer is one of the most common cancers and has became a predominant cause of cancer-related death throughout the world. The k-ras codon 12 mutation, which is the most common lung cancer mutation, is found in 15 to 30% of all lung cancers. Furthermore, the p53 gene has a very important role in the biological properties of tumor cells, and it is mutated in about 50% of non-small cell lung cancers. Residual tumor cells remain in surgical margins diagnosed as tumor free by histopathological techniques, and they can play a role in forming any local recurrence. Molecular methods may be exploited that are sensitive enough to detect small numbers of tumor cells. Methods: In the present study, we examined p53 gene mutations and k-ras codon 12 mutations from the tumor samples and surgical margins of 34 non-small-cell lung cancer patients. P53 gene mutations were analyzed by single strand conformational polymorphism analysis heterodublex analysis and DNA sequencing. K-ras codon 12 mutations were analyzed by the mutagenic PCR-restricted fragment length polymorphism method. Results: A p53 mutation was detected only in primary tumors of 3 out of 34 patients (8.82%). These mutations were clustered in exon 5. Moreover, a k-ras codon 12 mutation was detected in both the primary tumor and the surgical margin tissues of 2 out of 34 patients (5.88%). Conclusions: The detected mutation rate was low, in the range given in the literature. We think that different mechanisms related to other genes and individual genetic differences might play a role in cancer formation in our study group. We believe that molecular studies are necessary to identify biomarkers and to determine genetic alterations in histopathologically normal surgical margins

Tiroid ince iğne aspirasyonda hangi sitolojik özellikler papiller karsinom için daha değerlidir?

WOS: 000423909700009Aim: Fine-needle aspiration plays a significant role in the evaluation of solitary thyroid nodules. Several cytological criteria are defined and these primarily aim to distinguish papillary carcinoma (PC), the most common thyroid malignancy, from other benign diseases. In our study, we aimed to determine which cytologic criteria are more valuable in diagnosing PC. Methods: Patients, who had undergone thyroidectomy operation between January 2013 and December 2014 and had preoperative fine-needle aspiration cytology, were screened. Among cases that were postoperatively diagnosed as benign, 62 cases and among those diagnosed as PC and papillary microcarcinoma, 24 cases were included in this study. The cytologic criteria were reassessed. In the linear regression analysis, the variables associated with the diagnosis of malignancy at the level of p<0.05 were considered significant for predicting the diagnosis of PC. Results: The variables that remained as predictive for the diagnosis of cancer as the result of the Backward analysis following the multivariate analysis performed with the variables with a p value of less than 0.1 were cellular pleomorphism, nuclear atypia, papillary structures with fibrovascular cores, and intranuclear pseudoinclusion. Conclusion: Although every cytological feature is characteristic for PC, none of them alone is specific; they should be evaluated together with all nuclear and structural features during the diagnostic approach.Amaç:­Tiroidin soliter nodül değerlendirmesinde ince iğne aspirasyonu önemli bir rol oynar. Bir takım sitolojik kriterler tanımlanmış olup, bunlar öncelikle tiroid malignitesi içinde en sık rastlanılan papiller karsinomu (PK) diğer benign hastalıklardan ayırmayı amaçlar. Çalışmamızda hangi sitolojik kriterlerin PK tanısı koydurmada daha değerli olduğunu saptamayı amaçladık. Yöntemler: Hastanemizde Ocak 2013 ve Aralık 2014 tarihleri arasında tiroidektomi operasyonu gerçekleşen ve preoperatif dönemde ince iğne aspirasyon sitolojisi uygulanan olgular tarandı. Postoperatif tanısı benign olanlardan 62’si, PK ve papiller mikrokarsinomlardan 24’ü çalışmaya dahil edildi. Sitolojik değerlendirme kriterleri yeniden değerlendirildi. Lineer regresyon analizinde malignite tanısıyla p<0,05 düzeyinde ilişkili bulunan değişkenler PK tanısını öngörmede anlamlı kabul edildi. Bulgular: Çalışmamızda p<0,1 olan değişkenlerle çok değişkenli analiz yapılıp Backward analiz sonucunda kanser tanısını öngörmede anlamlı kalan değişkenler; hücresel pleomorfizm, nükleer atipi, fibrovasküler korlu papiller yapılar ve intranükleer psödoinklüzyondur. Sonuç: Her bir sitolojik özellik PK için karakteristik olmakla birlikte hiç birinin tek başına varlığı spesifik değildir. Tanı yaklaşımında tüm nükleer ve yapısal özelliklerle birlikte değerlendirilmelidir

f ur Mathematik in den Naturwissenschaften Leipzig A note on ows towards re ectors A NOTE ON FLOWS TOWARDS REFLECTORS

Abstract. A classical problem in geometric optics is to nd surfaces that re ect light from a given light source such that a prescribed intensity on a target is realized. We i n troduce a ow equation for surfaces such that they converge to solutions of this re ector problem both for closed hypersurfaces and for the illumination of prescribed domains