Imaginaries on ice:Sociotechnical futures of data centre development in Norway and Iceland

In 2018, Norway promoted itself as a ‘Datacentre Nation’. In terms of low cost, renewably generated sources of electricity and low ambient temperatures, Nordic countries and the data centre sector are potentially mutual beneficiaries – yet, there are also negative impacts associated with the necessary electric power production. With this as a starting point, for Norway and Iceland, we explore how data centre proponents promulgate similar techno-environmental imaginaries, but achieve differing degrees of stabilisation. To this end, we use three sources of imaginaries relating to data centre development in Iceland and Norway: those implicit in promotional imagery originating within the countries concerned; those implicit in international newspapers, as indicative of external perceptions; and those implicit in focus groups with the Norwegian and Icelandic public. We show how data centre advocates deploy visual imagery to create a promotional techno-environmental imaginary that marries nature with the digital in a symbiotic form, and we observe that this is largely consistent with the more mundane international imaginary of Norwegian data centres. For Iceland, however, the external imaginary is dominated by associations of excess energy consumption by bitcoin mining. For the publics questioned, there are multiple imaginaries of data centres, with significant notes of moral and other forms of scepticism. Looking ahead, we suggest that for long-term stabilisation of positive data centre imaginaries, conducive to investment, the capacity of Iceland and Norway to equitably supply sufficient renewable power will need to be addressed as a matter of urgency.</p

Connecting dots: multiple perspectives on socio-technical transition and social practices

This Crossing Boundary hosts contributions accounting for experiences and theoretical perspectives which may look distant for how they address the socio-technical transition in the energy field but, we believe, when put in conversation, help common questions and tentative answers come to the fore. Giorgio Osti, Paul Upham, Paula Maria Bagel and Paula Castro have been engaged in reflecting on their respective disciplines in relation to socio-technical transitions. Recalling and valorising the STS basis of MLP and SPT in connection with other disciplinary approaches may contribute to enrich on one side STS debates and on the other empirical research on socio-technical transition in a historical juncture where such an endeavour looks definitely urgent.info:eu-repo/semantics/publishedVersio

Evolution of the largest mammalian genome

The genome of the red vizcacha rat (Rodentia, Octodontidae, Tympanoctomys barrerae) is the largest of all mammals, and about double the size of their close relative, the mountain vizcacha rat Octomys mimax, even though the lineages that gave rise to these species diverged from each other only about five million years ago. The mechanism for this rapid genome expansion is controversial, and hypothesized to be a consequence of whole genome duplication or accumulation of repetitive elements. To test these alternative but nonexclusive hypotheses, we gathered and evaluated evidence from whole transcriptome and whole genome sequences of T. barrerae and O. mimax. We recovered support for genome expansion due to accumulation of a diverse assemblage of repetitive elements, which represent about one half and one fifth of the genomes of T. barrarae and O. mimax, respectively, but we found no strong signal of whole genome duplication. In both species, repetitive sequences were rare in transcribed regions as compared to the rest of the genome, and mostly had no close match to annotated repetitive sequences from other rodents. These findings raise new questions about the genomic dynamics of these repetitive elements, their connection to widespread chromosomal fissions that occurred in the T. barrerae ancestor, and their fitness effects ? including during the evolution of hypersaline dietary tolerance in T. barrerae.Fil: Evans, Ben J.. Mc Master University; CanadáFil: Upham, Nathan S.. Mc Master University; Canadá. Field Museum of Natural History; Estados Unidos. University of Yale; Estados UnidosFil: Golding, G. Brian. Mc Master University; CanadáFil: Ojeda, Ricardo Alberto. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Mendoza. Instituto Argentino de Investigaciones de las Zonas Áridas. Provincia de Mendoza. Instituto Argentino de Investigaciones de las Zonas Áridas. Universidad Nacional de Cuyo. Instituto Argentino de Investigaciones de las Zonas Áridas; ArgentinaFil: Ojeda, Agustina Alejandra. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Mendoza. Instituto Argentino de Investigaciones de las Zonas Áridas. Provincia de Mendoza. Instituto Argentino de Investigaciones de las Zonas Áridas. Universidad Nacional de Cuyo. Instituto Argentino de Investigaciones de las Zonas Áridas; Argentin

Making the internet globally sustainable: technical and policy options for improved energy management, governance and community acceptance of Nordic datacenters

Both policymakers and the technology industry need to do more to combat the ever-growing demand for data and its associated energy impacts. In this study, based on novel corporate data, expert interviews, focus groups with members of the public, extensive site visits across Greenland, Iceland and Norway and a literature review, we look at the energy and climate impacts of existing and proposed datacenters, both quantitatively and in terms of stakeholder and public perceptions. The paper examines datacenter management and sustainability practices in the Nordic region. It explores what community impacts occur, and how communities manage conflicting objectives. It investigates the technical and policy options that can make datacenters more sustainable and/or lower-carbon and it explores associated stakeholder and public views in the three countries. In exploring these themes, our study examines the shifting energy governance of datacenters, including patterns of electricity consumption and cooling but also circular economy operations and power densities. We also analyze a series of 40 solutions for eco-friendly design or green datacenter management across the entire lifecycle. We conclude with implications for energy and climate policy as well as future research

The “whole systems” energy sustainability of digitalization: humanizing the community risks and benefits of Nordic datacenter development

Digital platforms and the online services that they provide have become an indispensable and ubiquitous part of modern lifestyles, mediating our jobs, hobbies, patterns of consumption and forms of communication. However, no one is steering this development, or closely looking at the impacts that it may have on remote communities in the Arctic and Nordic region, a hotspot for datacenter development. Moreover, unlike other areas of energy consumption or technology adoption prone to rich, qualitative assessments, such work on datacenters involving local stakeholders and environmental concerns is less common, particularly at a larger scale. In this study, based on novel mixed methods—including corporate data, expert interviews, focus groups, and extensive site visits—across three countries, we offer a geographically and technologically bounded assessment looking at the sustainability impacts of datacenters on local communities. We ask: What impacts are occurring as part of datacenter development or planning proposals in Greenland, Iceland, and Norway? What is the actual and anticipated scale of those impacts on local Arctic communities? Finally, what impacts to datacenter development occur at the “whole systems” level? We examine not only impacts onsite at existing or proposed datacenters, but an entire range of consequences including the manufacturing of equipment, the laying of data cables, the construction of buildings, and issues of the dark web, cryptocurrency mining, hacking, spying, waste and decommissioning. Moreover, we humanize risks and benefits not only across scales, but also categorical types, including local impacts such as boom and bust cycles, the displacement of indigenous groups for land – particularly for power supply - and impacts on employment, especially after datacenters may close

Influenza epidemiology, vaccine coverage and vaccine effectiveness in children admitted to sentinel Australian hospitals in 2014: The influenza complications alert network (FluCAN)

The Influenza Complications Alert Network (FluCAN) is a sentinel hospital-based surveillance programme operating in all states and territories in Australia. We summarise the epidemiology of children hospitalised with laboratory-confirmed influenza in 2014 and reports on the effectiveness of inactivated trivalent inactivated vaccine (TIV) in children. In this observational study, cases were defined as children admitted with acute respiratory illness (ARI) with influenza confirmed by PCR. Controls were hospitalised children with ARI testing negative for influenza. Vaccine effectiveness (VE) was estimated as 1 minus the odds ratio of vaccination in influenza positive cases compared with test-negative controls using conditional logistic regression models. From April until October 2014, 402 children were admitted with PCR-confirmed influenza. Of these, 28% were aged < 1 year, 16% were Indigenous, and 39% had underlying conditions predisposing to severe influenza. Influenza A was detected in 90% of cases of influenza; influenza A(H1N1)pdm09 was the most frequent subtype (109/141 of subtyped cases) followed by A(H3N2) (32/141). Only 15% of children with influenza received antiviral therapy. The adjusted VE of one or more doses of TIV for preventing hospitalised influenza was estimated at 55.5% (95% confidence intervals (CI): 11.6–77.6%). Effectiveness against influenza A(H1N1)pdm09 was high (91.6%, 95% CI: 36.0–98.9%) yet appeared poor against H3N2. In summary, the 2014 southern hemisphere TIV was moderately effective against severe influenza in children. Significant VE was observed against influenza A(H1N1)pdm0

Influenza Vaccine Effectiveness against Hospitalisation with Confirmed Influenza in the 2010-11 Seasons: A Test-negative Observational Study

Immunisation programs are designed to reduce serious morbidity and mortality from influenza, but most evidence supporting the effectiveness of this intervention has focused on disease in the community or in primary care settings. We aimed to examine the effectiveness of influenza vaccination against hospitalisation with confirmed influenza. We compared influenza vaccination status in patients hospitalised with PCR-confirmed influenza with patients hospitalised with influenza-negative respiratory infections in an Australian sentinel surveillance system. Vaccine effectiveness was estimated from the odds ratio of vaccination in cases and controls. We performed both simple multivariate regression and a stratified analysis based on propensity score of vaccination. Vaccination status was ascertained in 333 of 598 patients with confirmed influenza and 785 of 1384 test-negative patients. Overall estimated crude vaccine effectiveness was 57% (41%, 68%). After adjusting for age, chronic comorbidities and pregnancy status, the estimated vaccine effectiveness was 37% (95% CI: 12%, 55%). In an analysis accounting for a propensity score for vaccination, the estimated vaccine effectiveness was 48.3% (95% CI: 30.0, 61.8%). Influenza vaccination was moderately protective against hospitalisation with influenza in the 2010 and 2011 seasons

The pesticide adjuvant, Toximul™, alters hepatic metabolism through effects on downstream targets of PPARα

AbstractPrevious studies demonstrated that chronic dermal exposure to the pesticide adjuvant (surfactant), Toximul™ (Tox), has significant detrimental effects on hepatic lipid metabolism. This study demonstrated that young mice dermally exposed to Tox for 12 days have significant increases in expression of peroxisomal acyl-CoA oxidase (mRNA and protein), bifunctional enzyme (mRNA) and thiolase (mRNA), as well as the P450 oxidizing enzymes Cyp4A10 and Cyp4A14 (mRNA and protein). Tox produced a similar pattern of increases in wild type adult female mice but did not induce these responses in PPARα-null mice. These data support the hypothesis that Tox, a heterogeneous blend of nonionic and anionic surfactants, modulates hepatic metabolism at least in part through activation of PPARα. Notably, all three groups of Tox-treated mice had increased relative liver weights due to significant accumulation of lipid. This could be endogenous in nature and/or a component(s) of Tox or a metabolite thereof. The ability of Tox and other hydrocarbon pollutants to induce fatty liver despite being PPARα agonists indicates a novel consequence of exposure to this class of chemicals, and may provide a new understanding of fatty liver in populations with industrial exposure

Vaccine strain affects seroconversion after influenza vaccination in COPD patients and healthy older people

Though clinical guidelines recommend influenza vaccination for chronic obstructive pulmonary disease (COPD) patients and other high-risk populations, it is unclear whether current vaccination strategies induce optimal antibody responses. This study aimed to identify key variables associated with strain-specific antibody responses in COPD patients and healthy older people. 76 COPD and 72 healthy participants were recruited from two Australian centres and inoculated with influenza vaccine. Serum strain-specific antibody titres were measured pre- and post-inoculation. Seroconversion rate was the primary endpoint. Antibody responses varied between vaccine strains. The highest rates of seroconversion were seen with novel strains (36–55%), with lesser responses to strains included in the vaccine in more than one consecutive year (27–33%). Vaccine responses were similar in COPD patients and healthy participants. Vaccine strain, hypertension and latitude were independent predictors of seroconversion. Our findings reassure that influenza vaccination is equally immunogenic in COPD patients and healthy older people; however, there is room for improvement. There may be a need to personalise the yearly influenza vaccine, including consideration of pre-existing antibody titres, in order to target gaps in individual antibody repertoires and improve protection