El Ciclo General de Ciencias Sociales en el IDAES desde la mirada de estudiantes y docentes : algunas convergencias y desencuentros

Tesis de LicenciaturaLa presente investigación pretende indagar en las concepciones sobre la universidad, lo universitario y lo académico de los estudiantes ingresantes Cohorte 2015 a las carreras de Sociología y Antropología pertenecientes al Instituto de Altos Estudios Sociales, así como también, las de los docentes de las materias introductorias de mencionadas carreras. En este sentido, se procura establecer una relación entre los puntos de vista de dos actores fundamentales de la institución universitaria.Fil: Terrón, Romina Verónica. Universidad Nacional de San Martín. Instituto de Altos Estudios Sociales; ArgentinaFil: García Ulibarri, Belén Andrea. Universidad Nacional de San Martín. Instituto de Altos Estudios Sociales; Argentin

Antimicrobial resistance phenotypes and genotypes of methicillin-resistant Staphylococcus aureus CC398 isolates from Spanish hospitals

Livestock-associated methicillin-resistant Staphylococcus aureus (LA-MRSA) of lineage CC398 is an emerging clone causing human infections but is mostly found in pigs. The aim of this study was to characterize the antimicrobial resistance phenotypes/genotypes of a collection of 137 MRSA CC398 isolates obtained in a previous study from 17 Spanish hospitals, using tetracycline resistance as marker for selection. A multidrug-resistant (MDR) phenotype was present in 79% of analysed isolates, with 17% of them resistant to at least six different antimicrobial families. All tetracycline-resistant isolates (n=137) carried the tetM gene and 75% also carried the tetK gene. Almost 50% of MRSA CC398 isolates showed macrolide and/or lincosamide resistance: a) 39% of isolates were ERYR-CLIR (all with constitutive phenotype), with 87% of them carrying the ermC gene, followed by msrA (25%), ermB (21%), vgaA (17%), ermA (6%), lsaB (4%), linA (2%), linB (2%), and ermT (2%, this isolate with the new spa-type t18071); and b) 9% of MRSA CC398 isolates showed the dissociated ERYS-CLIR phenotype carrying the linA, linB, lsaB and vgaA genes. Other antimicrobial resistance phenotypes in these MRSA CC398 isolates included resistance to ciprofloxacin (67%), aminoglycosides (21%), mupirocin (6%), chloramphenicol (4%) or fusidic acid (2%). The more common resistance genes detected for some of these antimicrobials were: aac(6’)-Ie-aph(2’’)-Ia (16%) and ant(4’)-Ia (12%) for aminoglycosides, and fexA (3%) for chloramphenicol. The high rate of MDR phenotypes with a wide range of antimicrobial resistance genes shown in this study reduce the potential therapeutic options in case of infections.This work was supported by the Agencia Estatal de Investigación (AEI) of Spain (project SAF2016-76571-R), the Fondo Europeo de Desarrollo Regional (FEDER) of the EU, and the Sociedad de Enfermedades Infecciosas del Norte (SEINORTE). Sara Ceballos and Laura Ruiz-Ripa had predoctoral fellowships of the University of La Rioja (Spain) during the experimental part of the study