Flexible Wirelessly Powered Implantable Device

Brain implantable devices have various limitations in terms of size, power, biocompatibility and mechanical properties that need to be addressed. This paper presents a neural implant that is powered wirelessly using a flexible biocompatible antenna. This delivers power to an LED at the end of the shaft to provide a highly efficient demonstration. The proposed design in this study combines mechanical properties and practicality given the numerous constraints of this implant typology. We have applied a modular structure approach to the design of this device considering three modules of antenna, conditioner circuit and shank. The implant was fabricated using a flexible substrate of Polyimide and encapsulated by PDMS for chronic implantation. In addition, finite element method COMSOL Multiphysics simulation of mechanical forces acting on the implant and shank was carried out to validate a viable shank conformation-encapsulation combination that will safely work under operational stress with a satisfactory margin of safety

International Consensus Statement on Rhinology and Allergy: Rhinosinusitis

Background: The 5 years since the publication of the first International Consensus Statement on Allergy and Rhinology: Rhinosinusitis (ICAR‐RS) has witnessed foundational progress in our understanding and treatment of rhinologic disease. These advances are reflected within the more than 40 new topics covered within the ICAR‐RS‐2021 as well as updates to the original 140 topics. This executive summary consolidates the evidence‐based findings of the document. Methods: ICAR‐RS presents over 180 topics in the forms of evidence‐based reviews with recommendations (EBRRs), evidence‐based reviews, and literature reviews. The highest grade structured recommendations of the EBRR sections are summarized in this executive summary. Results: ICAR‐RS‐2021 covers 22 topics regarding the medical management of RS, which are grade A/B and are presented in the executive summary. Additionally, 4 topics regarding the surgical management of RS are grade A/B and are presented in the executive summary. Finally, a comprehensive evidence‐based management algorithm is provided. Conclusion: This ICAR‐RS‐2021 executive summary provides a compilation of the evidence‐based recommendations for medical and surgical treatment of the most common forms of RS