4 research outputs found
The Effect Of Potassium Bromate On Some Haematological Parameters Of Wistar Rats
Potassium bromate used widely in foods has been associated with various
complications in humans. However there is paucity of literature on
adverse effects on haematological parameters. Thus we decided to carry
out an experimental study to determine the effects of potassium bromate
on some blood indices using Wister rats. Twenty (20) male Wister rats
aged 2-3 months obtained from the department of Veterinary Medicine,
University of Nigeria Nsukka were acclimatized for two weeks. They were
divided into five groups and fed with graded doses of potassium bromate
solution for six weeks. One of the groups served as the control. Pre
and post administration blood samples were collected and analyzed the
same day using standard methods. The results revealed significant
decrease in the platelet count when compared with the controls
(P<0.05). There were no statistically significant differences in the
mean Cell haemoglobin concentration, haematocrit, and total leukocyte
counts between the test and control rats. Potassium bromate is
injurious to health if consumed continuously and in high quantity. It
has been shown to reduce platelet count in rats, and thus may cause
thrombocytopenia in humans. It is therefore imperative to take adequate
measures to eliminate the use of potassium bromate in the preparation
of food product
Motivational Drives and Employee Performance: Evidence from Selected Universities in Nigeria.
Genetic studies of African populations: an overview on disease susceptibility and response to vaccines and therapeutics.
Africa is the ultimate source of modern humans and as such harbors more genetic variation than any other continent. For this reason, studies of the patterns of genetic variation in African populations are crucial to understanding how genes affect phenotypic variation, including disease predisposition. In addition, the patterns of extant genetic variation in Africa are important for understanding how genetic variation affects infectious diseases that are a major problem in Africa, such as malaria, tuberculosis, schistosomiasis, and HIV/AIDS. Therefore, elucidating the role that genetic susceptibility to infectious diseases plays is critical to improving the health of people in Africa. It is also of note that recent and ongoing social and cultural changes in sub-Saharan Africa have increased the prevalence of non-communicable diseases that will also require genetic analyses to improve disease prevention and treatment. In this review we give special attention to many of the past and ongoing studies, emphasizing those in Sub-Saharan Africans that address the role of genetic variation in human disease