2 research outputs found
High Lassa Fever activity in Northern part of Edo State, Nigeria: reanalysis of con\ufb01rmatory test results
The purpose was to establish simple statistics of the e\ufb00ects of
lassa fever in northern part of Edo State, Nigeria. Lassa fever
activity in the northern part of Edo state, Nigeria, was
con\ufb01rmed in 2004 by laboratory analysis of samples sent to
Bernhard\u2013Nocht Institute (BNI) for Tropical Medicine Hamburg,
Germany. The published report of that study is re-analysed to determine
in statistical terms, what the values presented in percentages
translate to in number of persons in the hospital and the area. In the
year 2004, 12,000 persons presented with febrile illness at Irrua
Specialist Teaching Hospital (ISTH), Irrua; 832 (6.5%) had lassa fever
con\ufb01rmed by reversetranscriptase-polymerase chain reaction
(RT-PCR). 4,096 (32.26%) of those with febrile illness had acute
infection as they tested positive for IgM antibody. 333 (33.33%) of
about 1000 sta\ufb00 of the hospital had sub-clinical infection as
they tested positive for IgG and negative for IgM antibody. At least
208 of the 832 patients (25%) of the hospital with con\ufb01rmed
lassa fever must have died in the year 2004. 967 (5.9%) of relatives or
members of the public who had contact with infected persons had
con\ufb01rmed lassa fever. 555 (66.67%) of those with con\ufb01rmed
lassa fever are close relatives. The epidemics occur in clusters of
households, houses, streets or villages. It is concluded that high
lassa fever activity in the area has wider e\ufb00ects than what is
observed in hospital admitted patients. Further seroepidemiological
survey involving large population sample in the area should be carried
out to establish more accurate seroepidemiological data on lassa fever.
This study is expected to impact positively on the generation of
political priority for the control of lassa fever in Nigeri
High Lassa Fever activity in Northern part of Edo State, Nigeria: reanalysis of confirmatory test results
The purpose was to establish simple statistics of the effects of
lassa fever in northern part of Edo State, Nigeria. Lassa fever
activity in the northern part of Edo state, Nigeria, was
confirmed in 2004 by laboratory analysis of samples sent to
Bernhard–Nocht Institute (BNI) for Tropical Medicine Hamburg,
Germany. The published report of that study is re-analysed to determine
in statistical terms, what the values presented in percentages
translate to in number of persons in the hospital and the area. In the
year 2004, 12,000 persons presented with febrile illness at Irrua
Specialist Teaching Hospital (ISTH), Irrua; 832 (6.5%) had lassa fever
confirmed by reversetranscriptase-polymerase chain reaction
(RT-PCR). 4,096 (32.26%) of those with febrile illness had acute
infection as they tested positive for IgM antibody. 333 (33.33%) of
about 1000 staff of the hospital had sub-clinical infection as
they tested positive for IgG and negative for IgM antibody. At least
208 of the 832 patients (25%) of the hospital with confirmed
lassa fever must have died in the year 2004. 967 (5.9%) of relatives or
members of the public who had contact with infected persons had
confirmed lassa fever. 555 (66.67%) of those with confirmed
lassa fever are close relatives. The epidemics occur in clusters of
households, houses, streets or villages. It is concluded that high
lassa fever activity in the area has wider effects than what is
observed in hospital admitted patients. Further seroepidemiological
survey involving large population sample in the area should be carried
out to establish more accurate seroepidemiological data on lassa fever.
This study is expected to impact positively on the generation of
political priority for the control of lassa fever in Nigeri